Biochemie und Zellbiologie

Forschung AG Gaubatz

Prof. Dr. Stefan Gaubatz

Biochemistry and Cell Biology
Am Hubland Süd
97074 Würzburg

Tel.: 0931 31-84138



Our main interest is transcriptional regulation of the mammalian cell cycle by the DREAM complex and Myb-MuvB (MMB). MMB together with the B-MYB transcription factor is a master activator of genes required for mitosis and cytokinesis.

We use biochemical and genetic methods to understand how DREAM, MuvB, B-MYB and its target genes contribute to normal proliferation, development and tumorigenesis.



Gründl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP and Gaubatz S (2020): Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes, PLOS Genetics doi:10.1371/journal.pgen.1008818 https://doi.org/10.1371/journal.pgen.1008818

Weinstock G and Gaubatz S (2019): One way to rule them all: G2/M gene regulation by oncogenic YAP1 and B-MYB. Molecular and Cellular Oncology 6:6 doi: 10.1080/23723556.2019.1648026

Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, Eyss von B & Gaubatz S (2019): The Myb-MuvB complex is required for YAP-dependent transcription of mitotic genes. Cell Reports  27:3533-3546.e7. doi: 10.1016/j.celrep.2019.05.071.




Open PhD position