Innate immune response to Chlamydia infection
Chlamydia is known as a ‘silent epidemic’ since infected patients often remain asymptomatic and are therefore not treated with antibiotics. Moreover, Chlamydia infections are frequently associated with co-infecting pathogens like Neisseria gonorrhoeae and HIV. In the course of infection, Chlamydia encounters the host innate immune cells responsible to clear the infection.
Our study focuses on the defence mechanisms that this pathogen adopts to subvert the host’s innate immune response and how this may support co-infection with other bacteria and viruses.