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    Chair of Microbiology

    Prof. Dr. Dagmar Beier

    Prof. Dr. Dagmar Beier

    Contact information:  

    Tel.: 31-84421
    E-mail: d.beier@biozentrum.uni-wuerzburg.de
    Room: C240

    Office hour:

    Tuesday, 10 - 11 h

    Marie Zachary

    Phone: 31 88406
    E-mail: marie.zachary@uni-wuerzburg.de
    Room: C207

    1983-1989:          Studies of Chemistry, University of Würzburg

    1989-1992:          Postgraduate studies in Biochemistry, University of Würzburg

    1992:                   PhD in Biochemistry

    1992-1995:          Postdoctoral Research Fellow, Chair of Microbiology, University of Würzburg

    1995-1998:          Postdoctoral Research Fellow, Immunobiological Research Institute Siena, Italy

    1998-2002:          Research Scientist, Chair of Microbiology, University of Würzburg

    2002:                   Habilitation (Microbiology) and Venia legendi, University of Würzburg

    2002-2009:          Assistant Professor, Chair of Microbiology, University of Würzburg

    since 2009:          Lecturer, Chair of Microbiology, University of Würzburg

    • Bauer S, Helmreich J, Zachary M, Kaethner M, Heinrichs E, Rudel T, Beier D. The sibling sRNAs NgncR_162 and NgncR_163 of Neisseria gonorrhoeae participate in the expression control of metabolic, transport and regulatory proteins. Microbiology. 2017 Oct 23. doi: 10.1099/mic.0.000548. [Epub ahead of print]

    • Tanwer P, Bauer S, Heinrichs E, Panda G, Saluja D, Rudel T, Beier D. Post-transcriptional regulation of target genes by the sRNA FnrS in Neisseria gonorrhoeae. Microbiology. 2017 Jul;163(7):1081-1092. doi: 10.1099/mic.0.000484.

    • Pernitzsch SR, Tirier SM, Beier D, Sharma CM. A variable homopolymeric G-repeat defines small RNA-mediated posttranscriptional regulation of a chemotaxis receptor in Helicobacter pylori. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):E501-10 doi: 10.1073/pnas.1315152111 "PMID: 24474799; PMCID: PMC3910625"

    • Bauer S, Endres M, Lange M, Schmidt T, Schumbrutzki C, Sickmann A, Beier D. Novel function assignment to a member of the essential HP1043 response regulator family of epsilon-proteobacteria. Microbiology. 2013 May 159(Pt 5):880-9. doi: 10.1099/mic.0.066548-0 PMID: 23475951

    • Fritsch F, Mauder N, Williams T, Weiser J, Oberle M, Beier D. The cell envelope stress response mediated by the LiaFSRLm three-component system of Listeria monocytogenes is controlled via the phosphatase activity of the bifunctional histidine kinase LiaSLm. Microbiology. 2011 Feb 157(Pt 2):373-86. doi: 10.1099/mic.0.044776-0 PMID: 21030435

    • Müller S, Götz M, Beier D. Histidine residue 94 is involved in pH sensing by histidine kinase ArsS of Helicobacter pylori. PLoS One. 2009 Sep 7;4(9):e6930 doi: 10.1371/journal.pone.0006930 "PMID: 19759826; PMCID: PMC2736386"

    • Mauder N, Williams T, Fritsch F, Kuhn M, Beier D. Response regulator DegU of Listeria monocytogenes controls temperature-responsive flagellar gene expression in its unphosphorylated state. J Bacteriol. 2008 Jul 190(13):4777-81. doi: 10.1128/JB.00258-08 "PMID: 18441066; PMCID: PMC2446787"

    • Beier D, Gross R. The BvgS/BvgA phosphorelay system of pathogenic Bordetellae: structure, function and evolution. Adv Exp Med Biol. "2008;631:149-60 doi: 10.1007/978-0-387-78885-2_10 PMID: 18792687

    • Josenhans C, Beier D, Linz B, Meyer TF, Suerbaum S. Pathogenomics of helicobacter. Int J Med Microbiol. 2007 Nov 297(7-8):589-600. PMID: 17416549

    • Link S, Schmitt K, Beier D, Gross R. Identification and regulation of expression of a gene encoding a filamentous hemagglutinin-related protein in Bordetella holmesii. BMC Microbiol. 2007 Nov 7;7:100 "PMID: 17988394; PMCID: PMC2225982"

    • Pflock M, Müller S, Beier D. The CrdRS (HP1365-HP1364) two-component system is not involved in ph-responsive gene regulation in the Helicobacter pylori Strains 26695 and G27. Curr Microbiol. 2007 Apr 54(4):320-4. PMID: 17375361

    • Pflock M, Bathon M, Schär J, Müller S, Mollenkopf H, Meyer TF, Beier D. The orphan response regulator HP1021 of Helicobacter pylori regulates transcription of a gene cluster presumably involved in acetone metabolism. J Bacteriol. 2007 Mar 189(6):2339-49. "PMID: 17220217; PMCID: PMC1899378"

    • Joseph B, Beier D. Global analysis of two-component gene regulation in H. pylori by mutation analysis and transcriptional profiling. Methods Enzymol. "2007;423:514-30 PMID: 17609149

    • Pflock M, Kennard S, Finsterer N, Beier D. Acid-responsive gene regulation in the human pathogen Helicobacter pylori. J Biotechnol. 2006 Oct 20;126(1):52-60. PMID: 16713649

    • Pflock M, Finsterer N, Joseph B, Mollenkopf H, Meyer TF, Beier D. Characterization of the ArsRS regulon of Helicobacter pylori, involved in acid adaptation. J Bacteriol. 2006 May 188(10):3449-62. "PMID: 16672598; PubMed Central PMCID: PMC1482845"

    • Beier D, Gross R. Regulation of bacterial virulence by two-component systems. Curr Opin Microbiol. 2006 Apr 9(2):143-52. PMID: 16481212

    • Müller S, Förster J, Beier D. Repeated sequence motifs in the Helicobacter pylori P1408 promoter do not affect its transcription. Microbiol Res. "2006;161(3):212-21 PMID: 16765837

    • Williams T, Joseph B, Beier D, Goebel W, Kuhn M. Response regulator DegU of Listeria monocytogenes regulates the expression of flagella-specific genes. FEMS Microbiol Lett. 2005 Nov 15;252(2):287-98 PMID: 16213668

    • Jimenez-Pearson MA, Delany I, Scarlato V, Beier D. Phosphate flow in the chemotactic response system of Helicobacter pylori. Microbiology. 2005 Oct 151(Pt 10):3299-311. PMID: 16207913

    • Pflock M, Kennard S, Delany I, Scarlato V, Beier D. Acid-induced activation of the urease promoters is mediated directly by the ArsRS two-component system of Helicobacter pylori. Infect Immun. 2005 Oct 73(10):6437-45. "PMID: 16177315; PMCID: PMC1230922"

    • Schär J, Sickmann A, Beier D. Phosphorylation-independent activity of atypical response regulators of Helicobacter pylori. J Bacteriol. 2005 May 187(9):3100-9. "PMID: 15838037; PMCID: PMC1082831"

    • Williams T, Bauer S, Beier D, Kuhn M. Construction and characterization of Listeria monocytogenes mutants with in-frame deletions in the response regulator genes identified in the genome sequence. Infect Immun. 2005 May 73(5):3152-9. "PMID: 15845524; PMCID: PMC1087338"

    • Jimenez-Pearson MA, Dietz P, Beier D. Protein-protein interaction of HP137 with histidine kinase HP244 does not contribute to flagellar regulation in Helicobacter pylori. Microbiol Res. "2005;160(3):299-305 PMID: 16035242

    • Gerlach G, Janzen S, Beier D, Gross R. Functional characterization of the BvgAS two-component system of Bordetella holmesii. Microbiology. 2004 Nov 150(Pt 11):3715-29. PMID: 15528658

    • Pflock M, Dietz P, Schär J, Beier D. Genetic evidence for histidine kinase HP165 being an acid sensor of Helicobacter pylori. FEMS Microbiol Lett. 2004 May 1;234(1):51-61 PMID: 15109719

    • Panthel K, Dietz P, Haas R, Beier D. Two-component systems of Helicobacter pylori contribute to virulence in a mouse infection model. Infect Immun. 2003 Sep 71(9):5381-5. "PMID: 12933888; PMCID: PMC187308"

    • König J, Bock A, Perraud AL, Fuchs TM, Beier D, Gross R. Regulatory factors of Bordetella pertussis affecting virulence gene expression. J Mol Microbiol Biotechnol. 2002 May 4(3):197-203. PMID: 11931547

    • Dietz P, Gerlach G, Beier D. Identification of target genes regulated by the two-component system HP166-HP165 of Helicobacter pylori. J Bacteriol. 2002 Jan 184(2):350-62. "PMID: 11751811; PMCID: PMC139590"