Chair of Cell and Developmental Biology (Zoology I)

    Nicola Jones

    Full list of publications

    Bartossek T*, Jones NG*, Schäfer C, Cvitković M, Glogger M, Mott HR, Kuper J, Brennich M, Carrington M, Smith A-S, Fenz S, Kisker C, Engstler M (2017). Structural basis for the shielding function of the dynamic trypanosome VSG coat. Nature Microbiology 2:1523-1532. doi: 10.1038/s41564-017-0013-6.Access the recommendation on F1000Prime

    Markert SM, Bauer V, Muenz TS, Jones NG, Helmprobst F, Britz S, Sauer M, Rössler W, Engstler M, Stigloher C (2017). 3D subcellular localization with superresolution array tomography on ultrathin sections of various species. Methods Cell Biol. 140:21-47. doi: 10.1016/bs.mcb.2017.03.004

    Zimmermann H, Subota I, Batram C, Kramer S, Janzen C, Jones NG, Engstler M (2017). A Quorum Sensing-independent Path to Stumpy Development in Trypanosoma brucei. Plos Pathogens. doi: 10.1371/journal.ppat.1006324.

    Hartel AJW, Glogger M, Jones NG, Abuillan W, Batram C, Hermann A, Fenz SF, Tanaka M, Engstler M (2016). N-glycosylation enables high lateral mobility of GPI-anchored proteins at a molecular crowding threshold. Nature Communications 7:12870. doi: 10.1038/ncomms12870.

    Hartel AJW, Glogger M, Guigas G, Jones NG, Fenz SF, Weiss M, Engstler M (2015). The molecular size of the extra-membrane domain influences the diffusion of the GPI-anchored VSG on the trypanosome plasma membrane. Scientific Reports 5:10394. doi: 10.1038/srep10394.

    Batram C, Jones NG, Janzen CJ, Markert SM, Engstler M (2014). Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei. eLife 3:e02324. doi: 10.7554/eLife.02324.

    Abuillan W, Vorobiev A, Hartel A, Jones NG, Engstler M, Tanaka M (2012). Quantitative determination of the lateral density and intermolecular correlation between proteins anchored on the membrane surfaces using grazing incidence small-angle X-ray scattering and grazing incidence X-ray fluorescence. The Journal of Chemical Physics 137:204907. doi: 10.1063/1.4767569.

    Harrington JM, Scelsi C, Hartel A, Jones NG, Engstler M, Capewell P, MacLeod A, Hajduk S (2012). Novel African Trypanocidal Agents: Membrane Rigidifying Peptides. PLoS ONE 7:e44384. doi: 10.1371/journal.pone.0044384.

    Hiltensperger G, Jones NG, Niedermeier S, Stich A, Kaiser M, Jung J, Puhl S, Damme A, Braunschweig H, Meinel L, et al. (2012). Synthesis and Structure-Activity Relationships of New Quinolone-Type Molecules against Trypanosoma brucei. Journal of Medicinal Chemistry 55:2538-2548. doi: 10.1021/jm101439s.

    Schwede A, Jones N, Engstler M, Carrington M (2011). The VSG C-terminal domain is inaccessible to antibodies on live trypanosomes. Molecular and Biochemical Parasitology 175:201-204. doi: 10.1016/j.molbiopara.2010.11.004.

    Field MC, Lumb JH, Adung’a VO, Jones NG, Engstler M (2009). Macromolecular trafficking and immune evasion in African trypanosomes. International Review of Cell and Molecular Biology 278:1-67. doi: 10.1016/S1937-6448(09)78001-3.

    Jones NG, Nietlispach D, Sharma R, Burke DF, Eyres I, Mues M, Mott HR, Carrington M (2008). Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein. The Journal of Biological Chemistry 283:3584-3593. doi: 10.1074/jbc.M706207200.

    Marcello L, Menon S, Ward P, Wilkes JM, Jones NG, Carrington M, Barry JD (2007). VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins. BMC Bioinformatics 8:143. doi: 10.1186/1471-2105-8-143.

    Hutchinson OC, Picozzi K, Jones NG, Mott H, Sharma R, Welburn SC, Carrington M (2007). Variant Surface Glycoprotein gene repertoires in Trypanosoma brucei have diverged to become strain-specific. BMC Genomics 8:234. doi: 10.1186/1471-2164-8-234.

    Chattopadhyay A, Jones NG, Nietlispach D, Nielsen PR, Voorheis HP, Mott HR, Carrington M (2005). Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2. The Journal of Biological Chemistry 280:7228-7235. doi: 10.1074/jbc.M410787200.

    Barry JD, Marcello L, Morrison LJ, Read AF, Lythgoe K, Jones N, Carrington M, Blandin G, Böhme U, Caler E, et al. (2005). What the genome sequence is revealing about trypanosome antigenic variation. Biochemical Society Transactions 33:986-989. doi: 10.1042/BST0330986.

    Kamp G, Busselmann G, Jones N, Wiesner B, Lauterwein J (2003). Energy metabolism and intracellular pH in boar spermatozoa. Reproduction (Cambridge, England) 126:517-525. doi: 10.1530/rep.0.1260517.

    Hutchinson OC, Smith W, Jones NG, Chattopadhyay A, Welburn SC, Carrington M (2003). VSG structure: similar N-terminal domains can form functional VSGs with different types of C-terminal domain. Molecular and Biochemical Parasitology 130, 127-131. doi: 10.1016/S0166-6851(03)00144-0.

    Bone W, Jones NG, Kamp G, Yeung CH, Cooper, TG (2000). Effect of ornidazole on fertility of male rats: inhibition of a glycolysis-related motility pattern and zona binding required for fertilization in vitro. Journal of Reproduction and Fertility 118, 127-135. doi: 10.1530/jrf.0.1180127


    Lehrstuhl für Zoologie I - Zell- und Entwicklungsbiologie
    Am Hubland
    97074 Würzburg

    Phone: +49 931 31-84250
    Fax: +49 931 31-84252

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    Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Julius-von-Sachs-Platz 2 Fabrikschleichach Hubland Süd, Geb. B2 Campus Medizin