Other Mg2+ Transporters TRPM7 Mg2+ P2X1 TP PAR1/4 KINASE GPVI P2Y1 P2Y12 IP RHO-A PLC IP3 DAG PI3K Ca2+ PKC SRC AKT a2b3 Aggregation ADPr 5-HT2A AC cAMP PKA VASP ATPr ATP TXA2 THROMBIN COLLAGEN ADP PGI2 5-HT 5-HTr RAP1 ORAI1 TRPC6 TXA2r MAPKC PLA2 IP3R sGC PKG cGMP NO CalDAG STIM1 ARHGEF1 ROCK1 TALIN1 RAC1 Granule release Shape Change + + + + + + + + + + + + + + + + + + + + + - - - - + - - + + + + + + + + + + + + + + + + + + + - + + + + + + - + + - + + + + + - - + + + + + + + + + + + -