AG Diefenbacher
Dr. Markus E. Diefenbacher
Lehrstuhl für Biochemie und Molekularbiologie
Biozentrum
Am Hubland
97074 Würzburg
Raum B 328/329
Tel: 0931 31-88167
Fax: 0931 31-84113
markus.diefenbacher@uni-wuerzburg.de
Our research focus is the deregulation of protein turnover as a central driver in tumourigenesis.
Research
E3-ligases; the double-edged sword
Deubiquitinases, a novel class of molecules in the limelight
E3-ligases and DUBs in lung cancer
E3-ligases and DUBs in intestinal cancer
Publications
Latest:
Cremona, C.A., Sancho, R., Diefenbacher, M.E. and Behrens, A. (2015). Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance. Seminars in cancer biology
Funding
Emil Hilb Programm
"Targeting protein stability in lung squamous cell carcinoma"
"Establishing a human colorectal cancer organoid bank" Collaboration with Armin Wiegering
"Unmasking E3-ligase-DUB pairs in colorectal cancer"
