Chair of Biochemistry and Molecular Biology

    AG Gallant

    Dr. Peter Gallant

    Lehrstuhl für Biochemie und Molekularbiologie
    Am Hubland
    97074 Würzburg
    Raum B 308

    Tel:   0931 31-88814
    Fax:  0931 31-84113

    The transcription factor Myc was initially identified as a potent proto-oncogene in vertebrates. Later it was shown to control a variety of physiological processes during normal development, most notably cellular growth and proliferation. These different activities of Myc can be largely explained by the nature of its transcriptional targets that have been identified in recent years. Much less is known, however, about the molecular mechanisms how Myc controls the expression of these targets in vivo.


    Molecular mechanism of transactivation by Myc in Drosophila Usefull Links: Flybase Bloomington Stock Center Vienna Drosophila RNAi Center (VDRC) SFB 1047 "Insect Timing"



    Jennifer M. Gerlach, Michael Furrer, Maria Gallant, Dirk Birkel, Apoorva Baluapuri, Elmar Wolf, and Peter Gallant (2017) PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters, PNAS, doi: 10.1073/pnas.1705816114

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