Dr. Hans Michael Maric | |
Telefon: | +49 931 31-85371 |
List of publications
2021[ to top ]
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Expanding GABAAR pharmacology via receptor-associated proteins in Current Opinion in Pharmacology (2021). 57 98–106.
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Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation in J. Am. Chem. Soc. (2021). 143(2) 891–901.
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Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases in Nature Communications (2021). 12(1) 62-.
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High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale in iScience (2021). 24(1) 101898-.
2020[ to top ]
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Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes in PLOS Genetics (2020). 16(5) e1008818-.
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A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition in J. Neurosci. (2020). 40(25) 4954-.
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Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells in EMBO Molecular Medicine (2020). 12(4) e11101-.
2019[ to top ]
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MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation in Nature Genetics (2019). 51(6) 990–998.
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MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation in Molecular Cell (2019). 74(4) 674–687.e11.
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Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins in Neuron (2019). 101(4) 673–689.e11.
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Targeting GABAAR-Associated Proteins: New Modulators, Labels and Concepts in Frontiers in Molecular Neuroscience (2019). 12 162-.
2018[ to top ]
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Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms in Journal of Molecular Biology (2018). 430(20) 3751–3763.
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Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin in Nature Communications (2018). 9(1) 3130-.
2017[ to top ]
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Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle in Cell Reports (2017). 21(12) 3483–3497.
2016[ to top ]
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Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling in Neuron (2016). 92(1) 126–142.
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Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission in Nature Chemical Biology (2016). 13 153-.
2015[ to top ]
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Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors in Angewandte Chemie International Edition (2015). 54(2) 490–494.
2014[ to top ]
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Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin in Nature Communications (2014). 5 5767-.
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Modulation of Gephyrin-Glycine Receptor Affinity by Multivalency in ACS Chem. Biol. (2014). 9(11) 2554–2562.
2012[ to top ]
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Gephyrin, the enigmatic organizer at GABAergic synapses in Frontiers in Cellular Neuroscience (2012). 6
2011[ to top ]
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Gephyrin-mediated γ-aminobutyric acid type A and glycine receptor clustering relies on a common binding site in The Journal of biological chemistry (2011). 286(49) 42105–42114.
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The Residence Time of GABAARs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin in J. Neurosci. (2011). 31(41) 14677-.
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Molecular Basis of the γ-Aminobutyric Acid A Receptor α3 Subunit Interaction with the Clustering Protein Gephyrin in Journal of Biological Chemistry (2011). 286(43) 37702–37711.