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    Chair of Biochemistry and Molecular Biology

    Welcome to our Department

    Our research focuses on the control of cell growth and proliferation and its deregulation in human tumors.

    We study transcription factors such as Myc and SREBP proteins that control gene expression programs involved in central biological processes such as cell cycle progression, apoptosis, protein translation and metabolism.

    Our work aims to understand how these factors work and how they are regulated and to use this knowledge for novel strategies for tumor therapy.

    The department is part of the
    Comprehensive Cancer Center Mainfranken.

    Event Announcements

    CCC Seminarreihe

    to be announced
    Referent: Anne Willis, Leicester University
    Ort: Biozentrum Universität Würzburg, Hörsaal A 101
    06. Juli 2018 17:00 c.t.
    Organisator: GSLS - CCC - FOR 2314 Seminarreihe

    New Publications

    Pedrotti L, Weiste C, Nägele T, Wolf E, Lorenzin F, DietrichK, Mair A, Weckwerth W, Teige M, Baena-González E, Dröge-Laser W (2018) Snf1-RELATEDKINASE1-Controlled C/S1-bZIP Signaling Activates Alternative MitochondrialMetabolic Pathways to Ensure Plant Survival in Extended Darkness. The Plantcell

    Rickman,D. S., Schulte, J. H., Eilers,M. (2017) The expanding world of N-Myc driven tumors. Cancer Discovery, in press

    Dejure,F.R., Eilers, M. (2017)MYC and tumor metabolism: chicken and egg. EMBO J. Nov 10. pii: e201796438.doi: 10.15252/embj.201796438. [Epub ahead of print] Review. PubMed PMID:29127156.

    Büchel, G., Carstensen, A., Mak, K.Y., Roeschert, I., Leen, E., Sumara, O., Hofstetter, J., Herold, S., Kalb, J., Baluapuri, A., Poon, E., Kwok, C., Chesler, L., Maric H. M., Rickman, D. S., Wolf, E., Bayliss, R., Walz, S., Eilers, M. Association with Aurora-A controls N-MYC-dependent promoter escape and pause release of RNA polymerase II during cell cycle (2017). Cell Reports in press

    Jennifer M. Gerlach, Michael Furrer, Maria Gallant, Dirk Birkel, Apoorva Baluapuri, Elmar Wolf, and Peter Gallant (2017) PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters, PNAS, doi: 10.1073/pnas.1705816114

    Klein-Hessling, S., Muhammad, K., Klein, M., Pusch, T., Rudolf, R., Floter, J., Qureischi, M., Beilhack, A., Vaeth, M., Kummerow, C., Backes, C., Schoppmeyer, R., Hahn, U., Hoth, M., Bopp, T., Berberich-Siebelt, F., Patra, A., Avots, A., Muller, N., Schulze, A. & Serfling, E. (2017) NFATc1 controls the cytotoxicity of CD8+ T cells, Nature Communication 8, 511.

    Open Positions

    If you are interested in working with us, please contact our administrative assistant, Sandra Stoudek, or contact the person you would like to work with directly.

    Prof. Dr. Martin Eilers

    Dr. Markus E. Diefenbacher

    Dr. Peter Gallant

    Prof. Dr. Almut Schulze

    PD Dr. Armin Wiegering

    Dr. Elmar Wolf -> Open Positions

    Contact

    Lehrstuhl für Biochemie und Molekularbiologie
    Am Hubland
    97074 Würzburg

    Phone: +49 931 31-84112
    Email

    Find Contact

    Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Julius-von-Sachs-Platz 2 Fabrikschleichach Hubland Süd, Geb. B2 Campus Medizin