Roeschert, I., Poon, E., Henssen, A.G., Dorado Garcia, H., Gatti, M., Giansanti, C., Jamin, Y., Ade, C.P., Gallant, P., Schülein-Völk, C., Beli, P., Richards, M., Rosenfeldt, M., Altmeyer, M., Anderson, J., Eggert, A., Dobbelstein, M., Bayliss, R., Chesler, L., Büchel, G., and Eilers, M.,: Combined inhibition of Aurora-A and ATR kinase resultsin regression of MYCN-amplifiedneuroblastoma, Nature Cancer (in press)
Adhikari, B., Bozilovic, J., Diebold, M.,Schwarz, JD., Hofstetter, J., Schröder, M., Wanior, M., Narain, A., Vogt, M., DudvarskiStankovic, N., Baluapuri, A., Schönemann, L., Eing, L., Bhandare, P., Kuster, B., Schlosser, A., Heinzlmeir, S., Sotriffer, C., Knapp, S., Wolf, E.,: PROTAC-mediated degradation reveals a non-catalytic function ofAURORA-A kinase, Nature Chemical Biology, 2020,
Endres, T., Solvie, D., Heidelberger, J., Andrioletti, V., Baluapuri, A., Ade, CP., Muhar, M., Eilers, U., Vos, SM., Cramer, P., Zuber, J., Beli, P., Popov, N., Wolf, E., Gallant, P., Eilers, M.: Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters, Molecular Cell, in press
Toboso-Navasa, A., Gunawan, A., Morlino, G., Nakagawa, R., Taddei, A., Damry, D., Patel, Y., Chakravarty, P., Janz. M., Kassiotis, G., Brink, R., Eilers, M., Calado, DP. (2020) Restriction of memory B cell differentiation at the 1 germinal center B cellpositive selection stage 23. J Exp Med. 217(7). pii: e20191933. doi: 10.1084/jem.20191933.
Prieto-Garcia, C., Hartmann, O., Reissland, M., Braun, F., Fischer, T., Walz, S., Schülein-Völk, C., Eilers, U., Ade, C.P., Calzado, M.A., Orian, A., Maric, H.M., Münch, C., Rosenfeldt, M., Eilers, M., Diefenbacher, M.E. Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells. EMBO Mol Med. 2020 Mar 4:e11101. doi: 10.15252/emmm.201911101. [Epub ahead of print] PubMed PMID: 32128997.
Baluapuri, A., Wolf, E., Eilers, M. (2020) Target gene-independent functions of Myc oncoproteins. Nat Rev Mol Cell Biol. 2020 Feb 18. doi: 10.1038/s41580-020-0215-2. [Epub ahead of print] Review
Cossa, G., Roeschert, I., Prinz, F., Baluapuri, A., R.S., V., Schülein-Völk, C., Chang, Y.-C., Ade, C. P., Mastrobuoni, G., Girard, C., Wortmann, L., Walz, S., Lührmann, R., Kempa, S., Kuster, B., Wolf, E., Mumberg, D., Eilers, M. (2020) Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription. Mol Cell. 2020 Jan 27. doi: 10.1016/j.molcel.2020.01.008. [Epub ahead of print]
Schmidt, S., Gay, D., Uthe, F. W., Denk, S., Paauwe, M., Matthes, N., Diefenbacher, M. E., Bryson, S., Warrander, F. C., Erhard, F., Ade, C. P., Baluapuri, A., Walz, S., Jackstadt, R. F., Vlachogiannis, G., Valeri, N., Otto, C., Schülein-Völk, C., Maurus, K., Schmitz, W., Knight, J. R. P., Wolf, E., Strathdee, D., Schulze, A., Germer, C-T., Rosenwald, A., Sansom, O. J., Eilers, M., Wiegering, A. A MYC/GCN2/eIF2a negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer. Nature Cell Biology. 2019, doi:10.1038/s41556-019-0408-0
Herold, S., Kalb, J., Buchel, G., Ade, C. P., Baluapuri, A., Xu, J., Koster, J., Solvie, D., Carstensen, A., Klotz, C., Rodewald, S., Schulein-Volk, C., Dobbelstein, M., Wolf, E., Molenaar, J., Versteeg, R., Walz, S., Eilers, M. (2019). Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA Polymerase. Nature. 2019 Mar;567(7749):545-549. doi: 10.1038/s41586-019-1030-9
Baluapuri, A., Hofstetter, J., Dudvarski Stankovic, N., Endres, T., Bhandare, P., Vos, S.M., Adhikari, B., Schwarz, J.D., Narain, A., Vogt, M., Wang, S.Y., Düster, R., Jung, L.A., Vanselow, J.T., Wiegering, A., Geyer, M., Maric, H.M., Gallant, P., Walz, S., Schlosser, A., Cramer, P., Eilers, M., Wolf, E. (2019) MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation. Mol Cell. 2019 May 16;74(4):674-687.e11.doi: 10.1016/j.molcel.2019.02.031.