Bioinformatik | Publikationen

2025[ to top ]
  • Paudel, R., Sorger, L., Hufnagel, A., Pasemann, M., Hove, T., Marquardt, A., Kneitz, S., Schlosser, A., Kisker, C., Kuper, J., & Meierjohann, S.Anti-tumorigenic properties by trichothiodystrophy mutations in melanocytic cellsNAR Cancer, 7(3). https://doi.org/10.1093/narcan/zcaf026.
2024[ to top ]
  • Münch, L., Helmprobst, F., Volff, J.-N., Chalopin, D., Schartl, M., & Kneitz, S.Transposable Element Expression Profiles in Premalignant Pigment Cell Lesions and Melanoma of XiphophorusGenes, 15(5): 620.
  • Schartl, M., Woltering, J.M., Irisarri, I., Du, K., Kneitz, S., Pippel, M., Brown, T., Franchini, P., Li, J., Li, M., Adolfi, M., Winkler, S., de Freitas Sousa, J., Chen, Z., Jacinto, S., Kvon, E.Z., Correa de Oliveira, L.R., Monteiro, E., Baia Amaral, D., et al.The genomes of all lungfish inform on genome expansion and tetrapod evolutionNature, 634(8032): 96–103.
  • Meinert, M., Jessen, C., Hufnagel, A., Kreß, J.K.C., Burnworth, M., Däubler, T., Gallasch, T., Xavier da Silva, T.N., dos Santos, A.F., Ade, C.P., Schmitz, W., Kneitz, S., Friedmann Angeli, J.P., & Meierjohann, S.Thiol starvation triggers melanoma state switching in an ATF4 and NRF2-dependent mannerRedox Biology, 70: 103011.
2023[ to top ]
  • Fetiva, M.C., Liss, F., Gertzmann, D., Thomas, J., Gantert, B., Vogl, M., Sira, N., Weinstock, G., Kneitz, S., Ade, C., & Gaubatz, S.Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migrationNucleic Acids Research, 51(9): 4266–4283.
  • Kotlyar, M.J., Krebs, M., Solimando, A.G., Marquardt, A., Burger, M., Kübler, H., Bargou, R., Kneitz, S., Otto, W., Breyer, J., Vergho, D.C., Kneitz, B., & Kalogirou, C.Critical Evaluation of a microRNA-Based Risk Classifier Predicting Cancer-Specific Survival in Renal Cell Carcinoma with Tumor Thrombus of the Inferior Vena CavaCancers, 15(7): 1981.
  • Lu, Y., Rice, E., Du, K., Kneitz, S., Naville, M., Dechaud, C., Volff, J.-N., Boswell, M., Boswell, W., Hillier, L., Tomlinson, C., Milin, K., Walter, R.B., Schartl, M., & Warren, W.C.High resolution genomes of multiple Xiphophorusspecies provide new insights into microevolution, hybrid incompatibility, and epistasisGenome Research, 33(4): 557–571.
2022[ to top ]
  • Martinez-Bengochea, A.L., Kneitz, S., Herpin, A., N\’o}brega, R.H., Adolfi, M.C., & Schartl, M.Sexual development dysgenesis in interspecific hybrids of Medaka fishScientific Reports, 12(1): 5408.
  • Du, K., Pippel, M., Kneitz, S., Feron, R., da Cruz, I., Winkler, S., Wilde, B., Avila Luna, E.G., Myers, G., Guiguen, Y., Macias Garcia, C., & Schartl, M.Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentationGenome Research, 32(3): 583–594.
  • Tamihardja, J., Zehner, L., Hartrampf, P., Lisowski, D., Kneitz, S., Cirsi, S., Razinskas, G., Flentje, M., & Polat, B.Salvage Nodal Radiotherapy as Metastasis-Directed Therapy for Oligorecurrent Prostate Cancer Detected by Positron Emission Tomography Shows Favorable Outcome in Long-Term Follow-UpCancers, 14(15): 3766.
  • Dedukh, D., da Cruz, I., Kneitz, S., Marta, A., Ormanns, J., Tichop\’a}d, T., Lu, Y., Alsheimer, M., Janko, K., & Schartl, M.Achiasmatic meiosis in the unisexual Amazon molly, Poecilia formosaChromosome Research, 30(4): 443–457.
2021[ to top ]
  • Adolfi, M.C., Du, K., Kneitz, S., Cabau, C., Zahm, M., Klopp, C., Feron, R., Paix\~a}o, R.V., Varela, E.S., de Almeida, F.L., de Oliveira, M.A., N\’o}brega, R.H., Lopez-Roques, C., Iampietro, C., Lluch, J., Kloas, W., Wuertz, S., Schaefer, F., St\"o}ck, M., et al.A duplicated copy of id2b is an unusual sex-determining candidate gene on the Y chromosome of arapaima (Arapaima gigas)Scientific Reports, 11(1): 21544.
  • Adolfi, M.C., Herpin, A., Martinez-Bengochea, A., Kneitz, S., Regensburger, M., Grunwald, D.J., & Schartl, M.Crosstalk Between Retinoic Acid and Sex-Related Genes Controls Germ Cell Fate and Gametogenesis in MedakaFrontiers in Cell and Developmental Biology, Volume 8 - 2020. https://doi.org/10.3389/fcell.2020.613497.
  • Feron, R., Pan, Q., Wen, M., Imarazene, B., Jouanno, E., Anderson, J., Herpin, A., Journot, L., Parrinello, H., Klopp, C., Kottler, V.A., Roco, A.S., Du, K., Kneitz, S., Adolfi, M., Wilson, C.A., McCluskey, B., Amores, A., Desvignes, T., et al.RADSex: A computational workflow to study sex determination using restriction site‐associated DNA sequencing dataMolecular Ecology Resources, 21(5): 1715–1731.
  • Helmprobst, F., Kneitz, S., Klotz, B., Naville, M., Dechaud, C., Volff, J.-N., & Schartl, M.Differential expression of transposable elements in the medaka melanoma modelPLOS ONE, 16(10): 1–17.
  • Schartl, M., Kneitz, S., Ormanns, J., Schmidt, C., Anderson, J.L., Amores, A., Catchen, J., Wilson, C., Geiger, D., Du, K., Garcia-Olazábal, M., Sudaram, S., Winkler, C., Hedrich, R., Warren, W.C., Walter, R., Meyer, A., & Postlethwait, J.H.The Developmental and Genetic Architecture of the Sexually Selected Male Ornament of SwordtailsCurrent Biology, 31(5): 911–922.e4.
  • Adolfi, M.C., Amaury, H., Martinez-Bengochea, A., Kneitz, S., Martina, R., Grunwald, D.J., & Schartl, M.Crosstalk Between Retinoic Acid and Sex-Related Genes Controls Germ Cell Fate and Gametogenesis in MedakaFrontiers in Cell and Developmental Biology, 8: 613497.
  • Meyer, A., Schloissnig, S., Franchini, P., Du, K., Woltering, J.M., Irisarri, I., Wong, W.Y., Nowoshilow, S., Kneitz, S., Kawaguchi, A., Fabrizius, A., Xiong, P., Dechaud, C., Spaink, H.P., Volff, J.-N., Simakov, O., Burmester, T., Tanaka, E.M., & Schartl, M.Giant lungfish genome elucidates the conquest of land by vertebratesNature, 590(7845): 284–289.
  • Vardapour, R., Kehl, T., Kneitz, S., Ludwig, N., Meese, E., Lenhof, H.-P., & Gessler, M.The DGCR8 E518K mutation found in Wilms tumors leads to a partial miRNA processing defect that alters gene expression patterns and biological processesCarcinogenesis, 43(2): 82–93.
  • Buschhart, A.-L., Bolten, L., Volzke, J., Ekat, K., Kneitz, S., Mikkat, S., Kreikemeyer, B., & Müller-Hilke, B.Periodontal pathogens alter the synovial proteome. Periodontal pathogens do not exacerbate macroscopic arthritis but alter the synovial proteome in micePLOS ONE, 15(12): 1–18.
2020[ to top ]
  • Schmidt, C.J., Wenndorf, K., Ebbers, M., Volzke, J., Müller, M., Strübing, J., Kriebel, K., Kneitz, S., Kreikemeyer, B., & Müller-Hilke, B.Infection With Clostridioides difficile Attenuated Collagen-Induced Arthritis in Mice and Involved Mesenteric Treg and Th2 PolarizationFrontiers in Immunology, Volume 11 - 2020. https://doi.org/10.3389/fimmu.2020.571049.
  • Krebs, M., Solimando, A.G., Kalogirou, C., Marquardt, A., Frank, T., Sokolakis, I., Hatzichristodoulou, G., Kneitz, S., Bargou, R., Kübler, H., Schilling, B., Spahn, M., & Kneitz, B.miR-221-3p Regulates VEGFR2 Expression in High-Risk Prostate Cancer and Represents an Escape Mechanism from Sunitinib In VitroJournal of Clinical Medicine, 9(3): 670.
  • Phan, Q.T., Tan, W.H., Liu, R., Sundaram, S., Buettner, A., Kneitz, S., Cheong, B., Vyas, H., Mathavan, S., Schartl, M., & Winkler, C.Cxcl9l and Cxcr3.2 regulate recruitment of osteoclast progenitors to bone matrix in a medaka osteoporosis modelProceedings of the National Academy of Sciences, 117(32): 19276–19286.
  • Du, K., St\"o}ck, M., Kneitz, S., Klopp, C., Woltering, J.M., Adolfi, M.C., Feron, R., Prokopov, D., Makunin, A., Kichigin, I., Schmidt, C., Fischer, P., Kuhl, H., Wuertz, S., Gessner, J., Kloas, W., Cabau, C., Iampietro, C., Parrinello, H., et al.The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidizationNature Ecology \& Evolution, 4(6): 841–852.
  • Lu, Y., Sandoval, A., Voss, S., Lai, Z., Kneitz, S., Boswell, W., Boswell, M., Savage, M., Walter, C., Warren, W., Schartl, M., & Walter, R.Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibilityProceedings of the National Academy of Sciences, 117(47): 29786–29794.
  • Kottler, V.A., Feron, R., Nanda, I., Klopp, C., Du, K., Kneitz, S., Helmprobst, F., Lamatsch, D.K., Lopez-Roques, C., Lluch, J., Journot, L., Parrinello, H., Guiguen, Y., & Schartl, M.Independent Origin of XY and ZW Sex Determination Mechanisms in Mosquitofish Sister SpeciesGenetics, 214(1): 193–209.
  • Jessen, C., Kre\ss}, J.K.C., Baluapuri, A., Hufnagel, A., Schmitz, W., Kneitz, S., Roth, S., Marquardt, A., Appenzeller, S., Ade, C.P., Glutsch, V., Wobser, M., Friedmann-Angeli, J.P., Mosteo, L., Goding, C.R., Schilling, B., Geissinger, E., Wolf, E., & Meierjohann, S.The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expressionOncogene, 39(44): 6841–6855.
2019[ to top ]
  • L\"u}bcke, P.M., Ebbers, M.N.B., Volzke, J., Bull, J., Kneitz, S., Engelmann, R., Lang, H., Kreikemeyer, B., & M\"u}ller-Hilke, B.Periodontal treatment prevents arthritis in mice and methotrexate ameliorates periodontal bone lossScientific Reports, 9(1): 8128.
  • Lu, Y., Boswell, W., Boswell, M., Klotz, B., Kneitz, S., Regneri, J., Savage, M., Mendoza, C., Postlethwait, J., Warren, W.C., Schartl, M., & Walter, R.B.Application of the Transcriptional Disease Signature (TDSs) to Screen Melanoma-Effective Compounds in a Small Fish ModelScientific Reports, 9(1): 530.
  • Krebs, M., Behrmann, C., Kalogirou, C., Sokolakis, I., Kneitz, S., Kruithof-de Julio, M., Zoni, E., Rech, A., Schilling, B., Kübler, H., Spahn, M., & Kneitz, B.miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1BioMed Research International, 2019: 1–11.
  • Pattschull, G., Walz, S., Gründl, M., Schwab, M., Rühl, E., Baluapuri, A., Cindric-Vranesic, A., Kneitz, S., Wolf, E., Ade, C.P., Rosenwald, A., von Eyss, B., & Gaubatz, S.The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic GenesCell Reports, 27(12): 3533 – 3546.e7.
  • Herpin, A., Schmidt, C., Kneitz, S., Gobé, C., Regensburger, M., Le Cam, A., Montfort, J., Adolfi, M.C., Lillesaar, C., Wilhelm, D., Kraeussling, M., Mourot, B., Porcon, B., Pannetier, M., Pailhoux, E., Ettwiller, L., Dolle, D., Guiguen, Y., & Schartl, M.A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medakaPLOS Biology, 17(4): 1–29.
  • Du, K., Wuertz, S., Adolfi, M., Kneitz, S., St\"o}ck, M., Oliveira, M., N\’o}brega, R., Ormanns, J., Kloas, W., Feron, R., Klopp, C., Parrinello, H., Journot, L., He, S., Postlethwait, J., Meyer, A., Guiguen, Y., & Schartl, M.The genome of the arapaima (Arapaima gigas) provides insights into gigantism, fast growth and chromosomal sex determination systemScientific Reports, 9(1): 5293.
  • Reuter, I., Jäckels, J., Kneitz, S., Kuper, J., Lesch, K.-P., & Lillesaar, C.Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafishBiology Open. https://doi.org/10.1242/bio.040683.
  • Blanco-Redondo, B., Nuwal, N., Kneitz, S., Nuwal, T., Halder, P., Liu, Y., Ehmann, N., Scholz, N., Mayer, A., Kleber, J., Kähne, T., Schmitt, D., Sadanandappa, M.K., Funk, N., Albertova, V., Helfrich-Förster, C., Ramaswami, M., Hasan, G., Kittel, R.J., et al.Implications of the Sap47 null mutation for synapsin phosphorylation, longevity, climbing, and behavioural plasticity in adult DrosophilaJournal of Experimental Biology. https://doi.org/10.1242/jeb.203505.
  • Klotz, B., Kneitz, S., Lu, Y., Boswell, W., Postlethwait, J., Warren, W., Walter, R.B., & Schartl, M.Expression Signatures of Cisplatin- and Trametinib-Treated Early-Stage Medaka MelanomasG3 Genes|Genomes|Genetics, 9(7): 2267–2276.
  • Schartl, M., Kneitz, S., Volkoff, H., Adolfi, M., Schmidt, C., Fischer, P., Minx, P., Tomlinson, C., Meyer, A., & Warren, W.C.The Piranha Genome Provides Molecular Insight Associated to Its Unique Feeding Behavior (E. Betran, Ed.)Genome Biology and Evolution, 11(8): 2099–2106.
2018[ to top ]
  • Kunz, M., L\"o}ffler-Wirth, H., Dannemann, M., Willscher, E., Doose, G., Kelso, J., Kottek, T., Nickel, B., Hopp, L., Landsberg, J., Hoffmann, S., T\"u}ting, T., Zigrino, P., Mauch, C., Utikal, J., Ziemer, M., Schulze, H.-J., H\"o}lzel, M., Roesch, A., et al.RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomasOncogene, 37(47): 6136–6151.
  • Lu, Y., Boswell, M., Boswell, W., Kneitz, S., Hausmann, M., Klotz, B., Regneri, J., Savage, M., Amores, A., Postlethwait, J., Warren, W., Schartl, M., & Walter, R.Comparison of Xiphophorus and human melanoma transcriptomes reveals conserved pathway interactionsPigment Cell &Amp; Melanoma Research, 31(4): 496–508.
  • Warren, W.C., Garc\’i}a-P{\’e}rez, R., Xu, S., Lampert, K.P., Chalopin, D., St\"o}ck, M., Loewe, L., Lu, Y., Kuderna, L., Minx, P., Montague, M.J., Tomlinson, C., Hillier, L.W., Murphy, D.N., Wang, J., Wang, Z., Garcia, C.M., Thomas, G.C.W., Volff, J.-N., et al.Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon mollyNature Ecology \& Evolution, 2(4): 669–679.
  • Tiwarekar, V., Wohlfahrt, J., Fehrholz, M., Scholz, C.-J., Kneitz, S., & Schneider-Schaulies, J.APOBEC3G-Regulated Host Factors Interfere with Measles Virus Replication: Role of REDD1 and Mammalian TORC1 Inhibition (R. E. Dutch, Ed.)Journal of Virology, 92(17). https://doi.org/10.1128/jvi.00835-18.
  • Lu, Y., Boswell, M., Boswell, W., Kneitz, S., Klotz, B., Savage, M., Salinas, R., Marks, R., Regneri, J., Postlethwait, J., Warren, W.C., Schartl, M., & Walter, R.Gene expression variation and parental allele inheritance in a Xiphophorus interspecies hybridization modelPLOS Genetics, 14(12): 1–16.
  • Klotz, B., Kneitz, S., Regensburger, M., Hahn, L., Dannemann, M., Kelso, J., Nickel, B., Lu, Y., Boswell, W., Postlethwait, J., Warren, W., Kunz, M., Walter, R.B., & Schartl, M.Expression signatures of early-stage and advanced medaka melanomasComparative Biochemistry and Physiology Part C: Toxicology &Amp; Pharmacology, 208: 20–28.
  • Anelli, V., Ordas, A., Kneitz, S., Sagredo, L.M., Gourain, V., Schartl, M., Meijer, A.H., & Mione, M.Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma ProgressionFrontiers in Genetics, Volume 9 - 2018. https://doi.org/10.3389/fgene.2018.00675.
  • Kruber, P., Angay, O., Winkler, A., Bösl, M.R., Kneitz, S., Heinze, K.G., & Gessler, M.Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formationInternational Journal of Cancer, 144(6): 1391–1400.
  • Regneri, J., Klotz, B., Wilde, B., Kottler, V.A., Hausmann, M., Kneitz, S., Regensburger, M., Maurus, K., Götz, R., Lu, Y., Walter, R.B., Herpin, A., & Schartl, M.Analysis of the putative tumor suppressor gene cdkn2ab in pigment cells and melanoma of Xiphophorus and medakaPigment Cell &Amp; Melanoma Research, 32(2): 248–258.
2017[ to top ]
  • Lu, Y., Boswell, M., Boswell, W., Kneitz, S., Hausmann, M., Klotz, B., Regneri, J., Savage, M., Amores, A., Postlethwait, J., Warren, W., Schartl, M., & Walter, R.Molecular genetic analysis of the melanoma regulatory locus in Xiphophorus interspecies hybridsMolecular Carcinogenesis, 56(8): 1935–1944.
  • Hupe, M., Li, M.X., Kneitz, S., Davydova, D., Yokota, C., Kele, J., Hot, B., Stenman, J.M., & Gessler, M.Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levelsScience Signaling, 10(487). https://doi.org/10.1126/scisignal.aag2476.
  • Silva-Vilches, C., Pletinckx, K., Lohnert, M., Pavlovic, V., Ashour, D., John, V., Vendelova, E., Kneitz, S., Zhou, J., Chen, R., Reinheckel, T., Mueller, T.D., Bodem, J., & Lutz, M.B.Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversionPLOS ONE, 12(7): 1–20.
  • Maurus, K., Hufnagel, A., Geiger, F., Graf, S., Berking, C., Heinemann, A., Paschen, A., Kneitz, S., Stigloher, C., Geissinger, E., Otto, C., Bosserhoff, A., Schartl, M., & Meierjohann, S.The AP-1 transcription factor FOSL1 causes melanocyte reprogramming and transformationOncogene, 36(36): 5110–5121.
2016[ to top ]
  • Endres, M., Kneitz, S., Orth, M.F., Perera, R.K., Zernecke, A., & Butt, E.Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)Oncotarget, 7(39): 64244–64259.
  • Kneitz, S., Mishra, R.R., Chalopin, D., Postlethwait, J., Warren, W.C., Walter, R.B., & Schartl, M.Germ cell and tumor associated piRNAs in the medaka and Xiphophorus melanoma modelsBMC Genomics, 17(1): 357.
  • Nekova, T.S., Kneitz, S., Einsele, H., Bargou, R., & Stuhler, G.Silencing of CDK2, but not CDK1, separates mitogenic from anti-apoptotic signaling, sensitizing p53 defective cells for synthetic lethalityCell Cycle, 15(23): 3203–3209.
2015[ to top ]
  • Leikam, C., Hufnagel, A.L., Otto, C., Murphy, D.J., M\"u}hling, B., Kneitz, S., Nanda, I., Schmid, M., Wagner, T.U., Haferkamp, S., Br\"o}cker, E.-B., Schartl, M., & Meierjohann, S.In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cellsCell Death \& Disease, 6(4): e1711-e1711.
  • Weber, D., Heisig, J., Kneitz, S., Wolf, E., Eilers, M., & Gessler, M.Mechanisms of epigenetic and cell-type specific regulation of Hey target genes in ES cells and cardiomyocytesJournal of Molecular and Cellular Cardiology, 79: 79–88.
  • Kang, J.H., Manousaki, T., Franchini, P., Kneitz, S., Schartl, M., & Meyer, A.Transcriptomics of two evolutionary novelties: how to make a sperm‐transfer organ out of an anal fin and a sexually selected “sword” out of a caudal finEcology and Evolution, 5(4): 848–864.
  • Simon, C.M., Rauskolb, S., Gunnersen, J.M., Holtmann, B., Drepper, C., Dombert, B., Braga, M., Wiese, S., Jablonka, S., P\"u}hringer, D., Zielasek, J., Hoeflich, A., Silani, V., Wolf, E., Kneitz, S., Sommer, C., Toyka, K.V., & Sendtner, M.Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathyActa Neuropathologica, 130(3): 373–387.
  • Wegert, J., Ishaque, N., Vardapour, R., Geörg, C., Gu, Z., Bieg, M., Ziegler, B., Bausenwein, S., Nourkami, N., Ludwig, N., Keller, A., Grimm, C., Kneitz, S., Williams, R., Chagtai, T., Pritchard-Jones, K., van Sluis, P., Volckmann, R., Koster, J., et al.Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms TumorsCancer Cell, 27(2): 298–311.
2014[ to top ]
  • Morton, C.O., Fliesser, M., Dittrich, M., Mueller, T., Bauer, R., Kneitz, S., Hope, W., Rogers, T.R., Einsele, H., & Loeffler, J.Gene Expression Profiles of Human Dendritic Cells Interacting with Aspergillus fumigatus in a Bilayer Model of the Alveolar Epithelium/Endothelium InterfacePLOS ONE, 9(5): 1–12.
  • Nekova, T.S., Kneitz, S., Einsele, H., & Stuhler, G.Silencing of Dicer1 temporally separates pro- and anti-apoptotic signaling and confers susceptibility to chemotherapy in p53 mutated cellsCell Cycle, 13(14): 2192–2198.
  • Vergho, D.C., Kneitz, S., Kalogirou, C., Burger, M., Krebs, M., Rosenwald, A., Spahn, M., Löser, A., Kocot, A., Riedmiller, H., & Kneitz, B.Impact of miR-21, miR-126 and miR-221 as Prognostic Factors of Clear Cell Renal Cell Carcinoma with Tumor Thrombus of the Inferior Vena CavaPLOS ONE, 9(10): 1–11.
  • Mishra, R.R., Kneitz, S., & Schartl, M.Comparative analysis of melanoma deregulated miRNAs in the medaka and Xiphophorus pigment cell cancer modelsComparative Biochemistry and Physiology Part C: Toxicology &Amp; Pharmacology, 163: 64–76.
  • Kneitz, B., Krebs, M., Kalogirou, C., Schubert, M., Joniau, S., van Poppel, H., Lerut, E., Kneitz, S., Scholz, C.J., Ströbel, P., Gessler, M., Riedmiller, H., & Spahn, M.Survival in Patients with High-Risk Prostate Cancer Is Predicted by miR-221, Which Regulates Proliferation, Apoptosis, and Invasion of Prostate Cancer Cells by Inhibiting IRF2 and SOCS3Cancer Research, 74(9): 2591–2603.
  • Saal, L., Briese, M., Kneitz, S., Glinka, M., & Sendtner, M.Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiationRNA, 20(11): 1789–1802.
  • Vergho, D., Kneitz, S., Rosenwald, A., Scherer, C., Spahn, M., Burger, M., Riedmiller, H., & Kneitz, B.Combination of expression levels of miR-21 and miR-126 is associated with cancer-specific survival in clear-cell renal cell carcinomaBMC Cancer, 14(1): 25.
  • Leikam, C., Hufnagel, A., Walz, S., Kneitz, S., Fekete, A., M\"u}ller, M.J., Eilers, M., Schartl, M., & Meierjohann, S.Cystathionase mediates senescence evasion in melanocytes and melanoma cellsOncogene, 33(6): 771–782.
2013[ to top ]
  • Gohlke, J., Scholz, C.-J., Kneitz, S., Weber, D., Fuchs, J., Hedrich, R., & Deeken, R.DNA Methylation Mediated Control of Gene Expression Is Critical for Development of Crown Gall TumorsPLOS Genetics, 9(2): 1–12.
  • Riedel, A., Mofolo, B., Avota, E., Schneider-Schaulies, S., Meintjes, A., Mulder, N., & Kneitz, S.Accumulation of Splice Variants and Transcripts in Response to PI3K Inhibition in T CellsPLOS ONE, 8(2): 1–12.
  • Bauer, H., Ache, P., Lautner, S., Fromm, J., Hartung, W., Al-Rasheid, K., Sonnewald, S., Sonnewald, U., Kneitz, S., Lachmann, N., Mendel, R., Bittner, F., Hetherington, A., & Hedrich, R.The Stomatal Response to Reduced Relative Humidity Requires Guard Cell-Autonomous ABA SynthesisCurrent Biology, 23(1): 53–57.
  • Schubert, M., Spahn, M., Kneitz, S., Scholz, C.J., Joniau, S., Stroebel, P., Riedmiller, H., & Kneitz, B.Distinct microRNA Expression Profile in Prostate Cancer Patients with Early Clinical Failure and the Impact of let-7 as Prognostic Marker in High-Risk Prostate CancerPLOS ONE, 8(6): 1–14.
  • Huang, B., Belharazem, D., Li, L., Kneitz, S., Schnabel, P., Rieker, R., Körner, D., Nix, W., Schalke, B., Müller-Hermelink, H.K., Ott, G., Rosenwald, A., Ströbel, P., & Marx, A.Anti-Apoptotic Signature in Thymic Squamous Cell Carcinomas – Functional Relevance of Anti-Apoptotic BIRC3 Expression in the Thymic Carcinoma Cell Line 1889cFrontiers in Oncology, Volume 3 - 2013. https://doi.org/10.3389/fonc.2013.00316.
  • Weißflog, L., Scholz, C.-J., Jacob, C.P., Nguyen, T.T., Zamzow, K., Groß-Lesch, S., Renner, T.J., Romanos, M., Rujescu, D., Walitza, S., Kneitz, S., Lesch, K.-P., & Reif, A.KCNIP4 as a candidate gene for personality disorders and adult ADHDEuropean Neuropsychopharmacology, 23(6): 436–447.
  • Jazbutyte, V., Fiedler, J., Kneitz, S., Galuppo, P., Just, A., Holzmann, A., Bauersachs, J., & Thum, T.MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heartAGE, 35(3): 747–762.
  • Bauer, H., Ache, P., Wohlfart, F., Al-Rasheid, K.A., Sonnewald, S., Sonnewald, U., Kneitz, S., Hetherington, A.M., & Hedrich, R.How Do Stomata Sense Reductions in Atmospheric Relative Humidity?Molecular Plant, 6(5): 1703–1706.
  • Kalogirou, C., Spahn, M., Krebs, M., Joniau, S., Lerut, E., Burger, M., Scholz, C.-J., Kneitz, S., Riedmiller, H., & Kneitz, B.MiR-205 Is Progressively Down-Regulated in Lymph Node Metastasis but Fails as a Prognostic Biomarker in High-Risk Prostate CancerInternational Journal of Molecular Sciences, 14(11): 21414–21434.
2012[ to top ]
  • Frantz, S., Hofmann, U., Fraccarollo, D., Schäfer, A., Kranepuhl, S., Hagedorn, I., Nieswandt, B., Nahrendorf, M., Wagner, H., Bayer, B., Pachel, C., Schön, M.P., Kneitz, S., Bobinger, T., Weidemann, F., Ertl, G., & Bauersachs, J.Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarctionThe FASEB Journal, 27(3): 871–881.
  • Schubert, M., Joniau, S., Gontero, P., Kneitz, S., Scholz, C.-J. rgen, Kneitz, B., Briganti, A., Karnes, R.J., Tombal, B., Walz, J., Hsu, C.-Y., Marchioro, G., Bader, P., Bangma, C., Frohneberg, D., Graefen, M., Schröder, F., van Cangh, P., van Poppel, H., et al.The Role of Adjuvant Hormonal Treatment after Surgery for Localized High-Risk Prostate Cancer: Results of a Matched Multiinstitutional AnalysisAdvances in Urology, 2012: 1–6.
  • Schartl, M., Kneitz, S., Wilde, B., Wagner, T., Henkel, C.V., Spaink, H.P., & Meierjohann, S.Conserved Expression Signatures between Medaka and Human Pigment Cell TumorsPLOS ONE, 7(5): 1–10.
  • Langenhorst, D., Gogishvili, T., Ribechini, E., Kneitz, S., McPherson, K., Lutz, M.B., & Hünig, T.Sequential Induction of Effector Function, Tissue Migration and Cell Death during Polyclonal Activation of Mouse Regulatory T-CellsPLOS ONE, 7(11): 1–11.
  • Heisig, J., Weber, D., Englberger, E., Winkler, A., Kneitz, S., Sung, W.-K., Wolf, E., Eilers, M., Wei, C.-L., & Gessler, M.Target Gene Analysis by Microarrays and Chromatin Immunoprecipitation Identifies HEY Proteins as Highly Redundant bHLH RepressorsPLOS Genetics, 8(5): 1–14.
  • Arias-Loza, P.-A., Kreissl, M.C., Kneitz, S., Kaiser, F.R., Israel, I., Hu, K., Frantz, S., Bayer, B., Fritzemeier, K.-H., Korach, K.S., & Pelzer, T.The Estrogen Receptor-α Is Required and Sufficient to Maintain Physiological Glucose Uptake in the Mouse HeartHypertension, 60(4): 1070–1077.
2011[ to top ]
  • Bartl, J., Scholz, C.-J., Hinterberger, M., Jungwirth, S., Wichart, I., Rainer, M.K., Kneitz, S., Danielczyk, W., Tragl, K.H., Fischer, P., Riederer, P., & Gr\"u}nblatt, E.Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading EnzymegeneBMC Medical Genetics, 12(1): 151.
  • Pletinckx, K., Stijlemans, B., Pavlovic, V., Laube, R., Brandl, C., Kneitz, S., Beschin, A., De Baetselier, P., & Lutz, M.B.Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2‐cell responsesEuropean Journal of Immunology, 41(12): 3479–3494.
  • Wegert, J., Bausenwein, S., Kneitz, S., Roth, S., Graf, N., Geissinger, E., & Gessler, M.Retinoic acid pathway activity in wilms tumors and characterization of biological responses in vitroMolecular Cancer, 10(1): 136.
  • Fiedler, J., Jazbutyte, V., Kirchmaier, B.C., Gupta, S.K., Lorenzen, J., Hartmann, D., Galuppo, P., Kneitz, S., Pena, J.T., Sohn-Lee, C., Loyer, X., Soutschek, J., Brand, T., Tuschl, T., Heineke, J., Martin, U., Schulte-Merker, S., Ertl, G., Engelhardt, S., et al.MicroRNA-24 Regulates Vascularity After Myocardial InfarctionCirculation, 124(6): 720–730.
  • Van den Hove, D., Jakob, S.B., Schraut, K.-G., Kenis, G., Schmitt, A.G., Kneitz, S., Scholz, C.-J., Wiescholleck, V., Ortega, G., Prickaerts, J., Steinbusch, H., & Lesch, K.-P.Differential Effects of Prenatal Stress in 5-Htt Deficient Mice: Towards Molecular Mechanisms of Gene × Environment InteractionsPLOS ONE, 6(8): 1–16.
  • Seher, A., Joachim, N., Mueller, T.D., Kneitz, S., Gebhardt, S., Meyer ter Vehn, T., Schlunck, G., & Sebald, W.Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitroMol Vis, 8(17): 53–62.
  • Beyrich, C., Löffler, J., Kobsar, A., Speer, C.P., Kneitz, S., & Eigenthaler, M.Infection of Human Coronary Artery Endothelial Cells by Group B Streptococcus Contributes to Dysregulation of Apoptosis, Hemostasis, and Innate Immune ResponsesMediators of Inflammation, 2011: 1–8.
  • Fraccarollo, D., Berger, S., Galuppo, P., Kneitz, S., Hein, L., Schütz, G., Frantz, S., Ertl, G., & Bauersachs, J.Deletion of Cardiomyocyte Mineralocorticoid Receptor Ameliorates Adverse Remodeling After Myocardial InfarctionCirculation, 123(4): 400–408.
  • Morton, C.O., Varga, J.J., Hornbach, A., Mezger, M., Sennefelder, H., Kneitz, S., Kurzai, O., Krappmann, S., Einsele, H., Nierman, W.C., Rogers, T.R., & Loeffler, J.The Temporal Dynamics of Differential Gene Expression in Aspergillus fumigatus Interacting with Human Immature Dendritic Cells In VitroPLOS ONE, 6(1): 1–18.
2010[ to top ]
  • Spahn, M., Kneitz, S., Scholz, C., Stenger, N., Rüdiger, T., Ströbel, P., Riedmiller, H., & Kneitz, B.Expression of microRNA‐221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrenceInternational Journal of Cancer, 127(2): 394–403.
  • Fleissner, F., Jazbutyte, V., Fiedler, J., Gupta, S.K., Yin, X., Xu, Q., Galuppo, P., Kneitz, S., Mayr, M., Ertl, G., Bauersachs, J., & Thum, T.Short Communication: Asymmetric Dimethylarginine Impairs Angiogenic Progenitor Cell Function in Patients With Coronary Artery Disease Through a MicroRNA-21–Dependent MechanismCirculation Research, 107(1): 138–143.
  • Scholz, C., Jacob, C.P., Buttenschon, H.N., Kittel‐Schneider, S., Boreatti‐Hümmer, A., Zimmer, M., Walter, U., Lesch, K., Mors, O., Kneitz, S., Deckert, J., & Reif, A.Functional variants of TSPAN8 are associated with bipolar disorder and schizophreniaAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 153B(4): 967–972.
2009[ to top ]
  • ENGELMANN, J.C., RAHMANN, S., WOLF, M., SCHULTZ, J., FRITZILAS, E., KNEITZ, S., DANDEKAR, T., & MÜLLER, T.Modelling cross‐hybridization on phylogenetic DNA microarrays increases the detection power of closely related speciesMolecular Ecology Resources, 9(1): 83–93.
2008[ to top ]
  • Meisner, F., Scheller, C., Kneitz, S., Sopper, S., Neuen-Jacob, E., Riederer, P., Meulen, V. ter, Koutsilieri, E., & for the German Competence Network HIV/AIDS.Memantine Upregulates BDNF and Prevents Dopamine Deficits in SIV-Infected Macaques: A Novel Pharmacological Action of MemantineNeuropsychopharmacology, 33(9): 2228–2236.
  • Mezger, M., Kneitz, S., Wozniok, I., Kurzai, O., Einsele, H., & Loeffler, J.Proinflammatory Response of Immature Human Dendritic Cells is Mediated by Dectin‐1 after Exposure toAspergillus fumigatusGerm TubesThe Journal of Infectious Diseases, 197(6): 924–931.
  • Fraccarollo, D., Galuppo, P., Schraut, S., Kneitz, S., van Rooijen, N., Ertl, G., & Bauersachs, J.Immediate Mineralocorticoid Receptor Blockade Improves Myocardial Infarct Healing by Modulation of the Inflammatory ResponseHypertension, 51(4): 905–914.
  • Schön, M., Wienrich, B.G., Kneitz, S., Sennefelder, H., Amschler, K., Vöhringer, V., Weber, O., Stiewe, T., Ziegelbauer, K., & Schön, M.P.KINK-1, a Novel Small-Molecule Inhibitor of IKKβ, and the Susceptibility of Melanoma Cells to Antitumoral TreatmentJNCI: Journal of the National Cancer Institute, 100(12): 862–875.
2007[ to top ]
  • Kneitz, S., Meisner, F., Sopper, S., Kaiser, F., Grünblatt, E., Scheller, C., Riederer, P., Meulen, V. ter, & Koutsilieri, E.Biostatistical analysis of gene microarrays reveals diverse expression clusters between macaque subspecies in brain SIV infectionIn Neuropsychiatric Disorders An Integrative Approach, 317–322 Vienna: Springer Vienna.
  • Lukashova v.Zangen, I., Kneitz, S., Monoranu, C.-M., Rutkowski, S., Hinkes, B., Vince, G.H., Huang, B., & Roggendorf, W.Ependymoma gene expression profiles associated with histological subtype, proliferation, and patient survivalActa Neuropathologica, 113(3): 325–337.
  • Thum, T., Galuppo, P., Wolf, C., Fiedler, J., Kneitz, S., van Laake, L.W., Doevendans, P.A., Mummery, C.L., Borlak, J., Haverich, A., Gross, C., Engelhardt, S., Ertl, G., & Bauersachs, J.MicroRNAs in the Human Heart: A Clue to Fetal Gene Reprogramming in Heart FailureCirculation, 116(3): 258–267.
2005[ to top ]
  • Muenzner, P., Rohde, M., Kneitz, S., & Hauck, C.R.CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cellsThe Journal of Cell Biology, 170(5): 825–836.
2004[ to top ]
  • Smolenski, A., Schultess, J., Danielewski, O., Garcia Arguinzonis, M.I., Thalheimer, P., Kneitz, S., Walter, U., & Lohmann, S.M.Quantitative analysis of the cardiac fibroblast transcriptome—implications for NO/cGMP signalingGenomics, 83(4): 577–587.
2001[ to top ]
  • Zavadil, J., Bitzer, M., Liang, D., Yang, Y.-C., Massimi, A., Kneitz, S., Piek, E., & Böttinger, E.P.Genetic programs of epithelial cell plasticity directed by transforming growth factor-βProceedings of the National Academy of Sciences, 98(12): 6686–6691.
1999[ to top ]
  • Park, J.H., Dixit, M.P., Onuchic, L.F., Wu, G., Goncharuk, A.N., Kneitz, S., Santarina, L.B., Hayashi, T., Avner, E.D., Guay-Woodford, L., Zerres, K., Germino, G.G., & Somlo, S.A 1-Mb BAC/PAC-Based Physical Map of the Autosomal Recessive Polycystic Kidney Disease Gene (PKHD1) Region on Chromosome 6Genomics, 57(2): 249–255.
  • Ruschenburg, I., Kneitz, S., Brinck, U., Korabiowska, M., Harms, H., & Droese, M.Myoepithelial sialadenitis versus low-grade non-Hodgkin’s lymphoma of the salivary gland in FNAB: is discrimination by means of an image processing system possible?In Vivo (Athens, Greece), 13(6): 515–518.
1998[ to top ]
  • Kneitz, S., Ott, G., Albert, R., Müller-Hermelink, H.K., & Harms, H.Differentiation of low-grade non-Hodgkin’s lymphomas using paraffin sections by image processingCytometry, 34(2): 75–81.
1996[ to top ]
  • and Kneitz, S., Ott, G., Albert, Schindewolf, T., Müller-Hermelink, H.K., & Harms, H.Differentiation of low grade non-Hodgkin’s lymphoma by digital image processingAnalytical and Quantitative Cytology and Histology, 18(2): 121–128.
  • Albert, R., Müller, J.G., Kristen, P., Schindewolf, T., Kneitz, S., & Harms, H.New method of nuclear grading of tissue sections by means of digital image analysis with prognostic significance for node-negative breast cancer patientsCytometry, 24(2): 140–150.

Nach oben