AG Häring | Publikationen
2023[ to top ]
-
How do molecular motors fold the genome?. Science 382, 646–648 (2023).
- [ DOI ]
2022[ to top ]
-
A hold-and-feed mechanism drives directional DNA loop extrusion by condensin. Science 376, 1087–1094 (2022).
- [ DOI ]
2020[ to top ]
-
The condensin holocomplex cycles dynamically between open and collapsed states. Nature Structural and Molecular Biology (2020) doi:10.1038/s41594-020-0508-3.
- [ DOI ]
-
Structural insights into DNA loop extrusion by SMC protein complexes. Current Opinion in Structural Biology 65, 102–109 (2020).
-
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism. Nature Structural and Molecular Biology 27, 743–751 (2020).
-
DNA-loop extruding condensin complexes can traverse one another. Nature 579, 438–442 (2020).
- [ DOI ]
2019[ to top ]
-
Structural Basis of an Asymmetric Condensin ATPase Cycle. Molecular Cell 74, 1175–1188 (2019).
-
Twist to disentangle. Nature Structural and Molecular Biology 26, 252–253 (2019).
-
Distinct Roles for Condensin’s Two ATPase Sites in Chromosome Condensation. Molecular Cell 76, 724–737.e5 (2019).
-
Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1. J Biol Chem 294, 13822–13829 (2019).
2018[ to top ]
-
Real-time imaging of DNA loop extrusion by condensin. Science 360, 102–105 (2018).
-
Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription. eLife 7, (2018).
-
Structural basis for Scc3-dependent cohesin recruitment to chromatin. eLife 7, (2018).
-
Towards a Unified Model of SMC Complex Function. Current Biology 28, R1266-R1281 (2018).
-
Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1. Journal of Cell Biology 217, 2383–2401 (2018).
2017[ to top ]
-
A Protocol for Measuring Mitotic Chromosome Condensation Quantitatively in Fission Yeast Cells. Methods Mol Biol 1515, 245–255 (2017).
-
Two independent modes of chromatin organization revealed by cohesin removal. Nature 551, 51–56 (2017).
-
Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes. Cell 171, 588–600.e24 (2017).
-
Real-time detection of condensin-driven DNA compaction reveals a multistep binding mechanism. The EMBO Journal 36, 3448–3457 (2017).
-
The condensin complex is a mechanochemical motor that translocates along DNA. Science 358, 672–676 (2017).
2016[ to top ]
-
SnapShot: SMC Protein Complexes Part I. Cell 164, 326–326.e1 (2016).
-
Condensin Smc2-Smc4 Dimers Are Flexible and Dynamic. Cell Reports 14, 1813–1818 (2016).
-
Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function. Cell Reports 14, 2116–2126 (2016).
-
SnapShot: SMC Protein Complexes Part II. Cell 164, 818–818.e1 (2016).
-
Nucleosome eviction in mitosis assists condensin loading and chromosome condensation. The EMBO Journal 35, 1565–1581 (2016).
2015[ to top ]
-
Control of chromosome interactions by condensin complexes. Current Opinion in Cell Biology 34, 94–100 (2015).
-
Shaping mitotic chromosomes: From classical concepts to molecular mechanisms. Bioessays 37, 755–66 (2015).
2014[ to top ]
-
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits. Nature Structural & Molecular Biology 21, 560–568 (2014).
-
Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation. Molecular Biology of the Cell 25, 2522–2536 (2014).
2013[ to top ]
-
Entrapment of Chromosomes by Condensin Rings Prevents Their Breakage during Cytokinesis. Developmental Cell 27, 469–478 (2013).
-
Quantitative analysis of chromosome condensation in fission yeast. Mol Cell Biol 33, 984–98 (2013).
- [ DOI ]
-
Condensin: crafting the chromosome landscape. Chromosoma 122, 175–190 (2013).
-
Understanding chromatin and chromosomes: from static views to dynamic thinking. EMBO reports 14, 109–111 (2013).
2012[ to top ]
-
Cohesin in determining chromosome architecture. Experimental Cell Research 318, 1386–1393 (2012).
- [ DOI ]
2011[ to top ]
-
A FlAsH-based cross-linker to study protein interactions in living cells. Angew Chem Int Ed Engl 50, 12655–8 (2011).
- [ DOI ]
-
Condensin structures chromosomal DNA through topological links. Nature Structural and Molecular Biology 18, 894–901 (2011).
- [ DOI ]
-
Condensin engages chromatin. Chembiochem 12, 2399–401 (2011).
- [ DOI ]
-
Deciphering condensin action during chromosome segregation. Trends in Cell Biology 21, 552–559 (2011).
- [ DOI ]
2010[ to top ]
-
A New Cohesive Team to Mediate DNA Looping. Cell Stem Cell 7, 424–426 (2010).
- [ DOI ]
-
A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion. The EMBO Journal 30, 364–378 (2010).
- [ DOI ]
2009[ to top ]
-
Cohesin: Its Roles and Mechanisms. Annual Review of Genetics 43, 525–558 (2009).
- [ DOI ]
-
Foreword: the many fascinating functions of SMC protein complexes. Chromosome Research 17, 127–129 (2009).
- [ DOI ]
2008[ to top ]
-
The cohesin ring concatenates sister DNA molecules. Nature 454, 297–301 (2008).
2006[ to top ]
-
Cohesin’s ATPase Activity Is Stimulated by the C-Terminal Winged-Helix Domain of Its Kleisin Subunit. Current Biology 16, 1998–2008 (2006).
- [ DOI ]
2005[ to top ]
-
THE STRUCTURE AND FUNCTION OF SMC AND KLEISIN COMPLEXES. Annual Review of Biochemistry 74, 595–648 (2005).
- [ DOI ]
2004[ to top ]
-
Structure and Stability of Cohesin’s Smc1-Kleisin Interaction. Molecular Cell 15, 951–964 (2004).
- [ DOI ]
2003[ to top ]
-
ATP Hydrolysis Is Required for Cohesin’s Association with Chromosomes. Current Biology 13, 1941–1953 (2003).
- [ DOI ]
-
Building and breaking bridges between sister chromatids. Bioessays 25, 1178–91 (2003).
-
Chromosomal Cohesin Forms a Ring. Cell 112, 765–777 (2003).
- [ DOI ]
2002[ to top ]
-
Molecular Architecture of SMC Proteins and the Yeast Cohesin Complex. Molecular Cell 9, 773–788 (2002).
-
Eco1 Is a Novel Acetyltransferase that Can Acetylate Proteins Involved in Cohesion. Current Biology 12, 323–328 (2002).
- [ DOI ]
2000[ to top ]
-
Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe. Proc Natl Acad Sci U S A 97, 6367–72 (2000).