AG Gaubatz | Publikationen

2023[ to top ]
  • Fetiva, M.C., Liss, F., Gertzmann, D., Thomas, J., Gantert, B., Vogl, M., Sira, N., Weinstock, G., Kneitz, S., Ade, C.P., & Gaubatz, S.Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migrationNucleic Acids Research.
2022[ to top ]
  • Hanselmann, S., Gertzmann, D., Shin, W.J., Ade, C.P., & Gaubatz, S.Expression of the cytokinesis regulator PRC1 results in p53-pathway activation in A549 cells but does not directly regulate gene expression in the nucleusCell Cycle, 1–14.
2021[ to top ]
  • Leone, M., Cazorla-V\’a}}zquez, S., Ferrazzi, F., Wiederstein, J.L., Gründl, M., Weinstock, G., Vergarajauregui, S., Eckstein, M., Krüger, M., Gaubatz, S., & Engel, F.B.IQGAP3, a YAP Target, Is Required for Proper Cell-Cycle Progression and Genome StabilityMolecular Cancer Research, 19(10): 1712–1726.
2020[ to top ]
  • Gründl, M., Walz, S., Hauf, L., Schwab, M., Werner, K.M., Spahr, S., Schulte, C., Maric, H.M., Ade, C.P., & Gaubatz, S.Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytesPLOS Genetics, 16(5): 1–27.
2019[ to top ]
  • Pattschull, G., Walz, S., Gründl, M., Schwab, M., Rühl, E., Baluapuri, A., Cindric-Vranesic, A., Kneitz, S., Wolf, E., Ade, C.P., Rosenwald, A., von Eyss, B., & Gaubatz, S.The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic GenesCell Reports, 27(12): 3533 – 3546.e7.
  • Weinstock, G., & Gaubatz, S.One way to rule them all: G2/M gene regulation by oncogenic YAP1 and B-MYBMolecular \& Cellular Oncology, 6(6): e1648026.
2017[ to top ]
  • Hanselmann, S., Wolter, P., Malkmus, J., & Gaubatz, S.The microtubule-associated protein PRC1 is a potential therapeutic target for lung cancerOncotarget, 9(4): 4985–4997.
  • Stopp, S., Gründl, M., Fackler, M., Malkmus, J., Leone, M., Naumann, R., Frantz, S., Wolf, E., von Eyss, B., Engel, F.B., & Gaubatz, S.Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during developmentProceedings of the National Academy of Sciences, 114(30): 8029–8034.
  • Wolter, P., Hanselmann, S., Pattschull, G., Schruf, E., & Gaubatz, S.Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapyOncotarget, 8(7): 11160–11172.
  • Gründl, M., Engel, F.B., & Gaubatz, S.GAS2L3: Coordinator of cardiomyocyte cytokinesis?Cell Cycle, 16(20): 1853–1854.
2016[ to top ]
  • Iltzsche, F., Simon, K., Stopp, S., Pattschull, G., Francke, S., Wolter, P., Hauser, S., Murphy, D.J., Garcia, P., Rosenwald, A., & Gaubatz, S.An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinomaOncogene, 36(1): 110–121.
2014[ to top ]
  • Fackler, M., Wolter, P., & Gaubatz, S.The GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscissionFEBS Journal, 281(9): 2123–2135.
  • Kumari, G., Ulrich, T., Krause, M., Finkernagel, F., & Gaubatz, S.Induction of p21CIP1 Protein and Cell Cycle Arrest after Inhibition of Aurora B Kinase Is Attributed to Aneuploidy and Reactive Oxygen SpeciesJournal of Biological Chemistry, 289(23): 16072–16084.
2013[ to top ]
  • Esterlechner, J., Reichert, N., Iltzsche, F., Krause, M., Finkernagel, F., & Gaubatz, S.LIN9, a Subunit of the DREAM Complex, Regulates Mitotic Gene Expression and Proliferation of Embryonic Stem CellsPLOS ONE, 8(5): 1–14.
  • Kumari, G., Ulrich, T., & Gaubatz, S.A role for p38 in transcriptional elongation of p21(CIP) in response to Aurora B inhibitionCell Cycle, 12(13): 2051–2060.
2012[ to top ]
  • Wolter, P., Schmitt, K., Fackler, M., Kremling, H., Probst, L., Hauser, S., Gruss, O.J., & Gaubatz, S.GAS2L3, a novel target gene of the dream complex, is required for proper cytokinesis and genomic stabilityJournal of Cell Science.
2011[ to top ]
  • Houben, R., Adam, C., Baeurle, A., Hesbacher, S., Grimm, J., Angermeyer, S., Henzel, K., Hauser, S., Elling, R., Bröcker, E.-B., Gaubatz, S., Becker, J.C., & Schrama, D.An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cellsInternational Journal of Cancer, 130(4): 847–856.
  • Hauser, S., Ulrich, T., Wurster, S., Schmitt, K., Reichert, N., & Gaubatz, S.Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growthOncogene, 31(14): 1859–1868.
2010[ to top ]
  • Reichert, N., Wurster, S., Ulrich, T., Schmitt, K., Hauser, S., Probst, L., Götz R., Ceteci, F., Moll, R., Rapp, U., & Gaubatz, S.Lin9, a Subunit of the Mammalian DREAM Complex, Is Essential for Embryonic Development, for Survival of Adult Mice, and for Tumor SuppressionMolecular and Cellular Biology, 30(12): 2896–2908.
  • Meierjohann, S., Hufnagel, A., Wende, E., Kleinschmidt, M.A., Wolf, K., Friedl, P., Gaubatz, S., & Schartl, M.MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferationMolecular Cancer, 9(1): 201-.
2009[ to top ]
  • Schmit, F., Cremer, S., & Gaubatz, S.LIN54 is an essential core subunit of the DREAM/LINC complex that binds to the cdc2 promoter in a sequence‐specific mannerThe FEBS Journal, 276(19): 5703–5716.
  • Mannefeld, M., Klassen, E., & Gaubatz, S.B-MYB Is Required for Recovery from the DNA Damage\textendashInduced G2 Checkpoint in p53 Mutant CellsCancer Research, 69(9): 4073–4080.
  • Kleinschmidt, M.A., Wagner, T.U., Liedtke, D., Spahr, S., Samans, B., & Gaubatz, S.lin9 Is Required for Mitosis and Cell Survival during Early Zebrafish DevelopmentJournal of Biological Chemistry, 284(19): 13119–13127.
2008[ to top ]
  • Kehoe, S.M., Oka, M., Hankowski, K.E., Reichert, N., Garcia, S., McCarrey, J.R., Gaubatz, S., & Terada, N.A Conserved E2F6-Binding Element in Murine Meiosis-Specific Gene PromotersBiology of Reproduction, 79(5): 921–930.
2007[ to top ]
  • Schmit, F., Korenjak, M., Mannefeld, M., Schmitt, K., Franke, C., von Eyss, B., Gagrica, S., Hänel, F., Brehm, A., & Gaubatz, S.LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genesCell Cycle, 6(15): 1903–1913.
2006[ to top ]
  • Osterloh, L., von Eyss, B., Schmit, F., Rein, L., Hübner, D., Samans, B., Hauser, S., & Gaubatz, S.The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosisThe EMBO Journal, 26(1): 144–157.
2005[ to top ]
  • Storre, J., Schäfer, A., Reichert, N., Barbero, J.L., Hauser, S., Eilers, M., & Gaubatz, S.Silencing of the Meiotic Genes SMC1β and STAG3 in Somatic Cells by E2F6Journal of Biological Chemistry, 280(50): 41380–41386.
2004[ to top ]
  • Giangrande, P.H., Zhu, W., Schlisio, S., Sun, X., Mori, S., Gaubatz, S., & Nevins, J.R.A role for E2F6 in distinguishing G1/S- and G2/M-specific transcriptionGenes &Amp; Development, 18(23, /content/18/23.cover.gif): 2941–2951.
  • Gagrica, S., Hauser, S., Kolfschoten, I., Osterloh, L., Agami, R., & Gaubatz, S.Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated proteinThe EMBO Journal, 23(23): 4627–4638.
2003[ to top ]
  • Ohtani, N., Brennan, P., Gaubatz, S., Sanij, E., Hertzog, P., Wolvetang, E., Ghysdael, J., Rowe, M., & Hara, E.Epstein-Barr virus LMP1 blocks p16INK4a\textendashRB pathway by promoting nuclear export of E2F4/5Journal of Cell Biology, 162(2): 173–183.
2002[ to top ]
  • Ogawa, H., Ishiguro, K., Gaubatz, S., Livingston, D.M., & Nakatani, Y.A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cellsScience, 296(5570): 1132–1136.
  • Dahme, T., Wood, J., Livingston, D.M., & Gaubatz, S.Two different E2F6 proteins generated by alternative splicing and internal translation initiationEur J Biochem, 269(20): 5030–5036.
  • Storre, J., Elsässer, H.-P., Fuchs, M., Ullmann, D., Livingston, D., & Gaubatz, S.Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2F6EMBO Reports, 3: 695–700.
2001[ to top ]
  • Gaubatz, S., Lees, J.A., Lindeman, G.J., & Livingston, D.M.E2F4 is exported from the nucleus in a CRM1-dependent mannerMol Cell Biol, 21(4): 1384–1392.
2000[ to top ]
  • Gaubatz, S., Lindeman, G.J., Ishida, S., Jakoi, L., Nevins, J.R., Livingston, D.M., & Rempel, R.E.E2F4 and E2F5 play an essential role in pocket protein-mediated G1 controlMol Cell, 6(3): 729–735.
1999[ to top ]
  • Elliott, K., Sakamuro, D., Basu, A., Du, W., Wunner, W., Staller, P., Gaubatz, S., Zhang, H., Prochownik, E., Eilers, M., & Prendergast, G.C.Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanismsOncogene, 18(24): 3564–3573.
1998[ to top ]
  • Gaubatz, S., Wood, J.G., & Livingston, D.M.Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6Proc Natl Acad Sci USA, 95(16): 9190–9195.
  • Lindeman, G.J., Dagnino, L., Gaubatz, S., Xu, Y., Bronson, R.T., Warren, H.B., & Livingston, D.M.A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targetingGenes Dev, 12(8): 1092–1098.
1997[ to top ]
  • Lindeman, G.J., Gaubatz, S., Livingston, D.M., & Ginsberg, D.The subcellular localization of E2F-4 is cell-cycle dependentProc Natl Acad Sci U S A, 94(10): 5095–5100.
1996[ to top ]
  • Desbarats, L., Gaubatz, S., & Eilers, M.Discrimination between different E-box-binding proteins at an endogenous target gene of c-mycGenes Dev, 10(4): 447–460.
1995[ to top ]
  • Gaubatz, S., Imhof, A., Dosch, R., Werner, O., Mitchell, P., Buettner, R., & Eilers, M.Transcriptional activation by Myc is under negative control by the transcription factor AP-2EMBO J, 14(7): 1508–1519.
1994[ to top ]
  • Gaubatz, S., Meichle, A., & Eilers, M.An E-box element localized in the first intron mediates regulation of the prothymosin alpha gene by c-mycMol Cell Biol, 14(6): 3853–3862.
1992[ to top ]
  • K\"u}es, U., Richardson, W.V., Tymon, A.M., Mutasa, E.S., G\"o}ttgens, B., Gaubatz, S., Gregoriades, A., & Casselton, L.A.The combination of dissimilar alleles of the A alpha and A beta gene complexes, whose proteins contain homeo domain motifs, determines sexual development in the mushroom Coprinus cinereusGenes Dev, 6(4): 568–577.

Nach oben