piwik-script

English
    AG Raabe

    Publikationen

    • Pütz, S.M. (2019). Mbt/PAK4 together with SRC modulates N-Cadherin adherens junctions in the developing Drosophila eye. Biol. Open 8, bio038406.
    • Fischer, M., Raabe, T. (2018) Animal models for Coffin-Lowry Syndrome: RSK2 and nervous system dysfunction. Front. Behav. Neurosci. 12, 106.
    • Beck, K., Hovhanyan, A., Menegazzi, P., Helfrich-Förster, C., Raabe, T. (2018) RSK influences the pace of the circadian clock by negative regulation of protein kinase Shaggy activity. Front. Mol. Neurosci. 11, 122.
    • Blumröder, R., Glunz, A., Dunkelberger, B.S., Serway, C.N., Berger, C., Mentzel, B., de Belle, J.S., Raabe, T. (2016) Mcm3 replicative helicase mutation impairs neuroblast proliferation and memory in Drosophila. Genes, Brain & Behav. 15, 647-659.
    • Cate, A.S., Gajendra, S., Alsbury, S., Raabe, T., Tear, G., Mitchell, K.J. (2016) Mushroom body defect is required in parallel to Netrin for midline axon guidance in Drosophila. Development 143, 972-977.
    • Beck, K., Ehmann, N., Andlauer, T.F.M., Ljaschenko, D., Strecker, K., Fischer, M., Kittel, R.J., Raabe, T. (2015) Loss of the Coffin-Lowry syndrome-associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons. Dis. Models Mech. 8, 1389-1400.
    • Herter, E.K., Strauch, M., Gallant, M., Wolf, E., Raabe, T., Gallant, P. (2015) snoRNAs are a novel class of biologically relevant Myc targets. BMC Biol. 13(1):25.
    • Dusik, V., Senthilan, P.R., Mentzel, B., Hartlieb, H,, Wülbeck, C., Yoshii, T., Raabe, T., Helfrich-Förster, C. (2014) The MAP Kinase p38 Is Part of Drosophila melanogaster's Circadian Clock. PLoS Genet. 10(8):e1004565.
    • Hovhanyan, A., Herter, E.K., Pfannstiel, J., Gallant, P., Raabe, T. (2014) Drosophila Mbm is a nucleolar Myc and Casein kinase 2 target required for ribosome biogenesis and cell growth of central brain neuroblasts. Mol. Cell. Biol. 34, 1878-1891.
    • Szabó A, Papin C, Zorn D, Ponien P, Weber F, Raabe T, Rouyer F. (2013) The CK2 Kinase Stabilizes CLOCK and Represses Its Activity in the Drosophila Circadian Oscillator. PLoS Biol. 11(8):e1001645.
    • Melzer, J., Kraft, K.F., Urbach, R., Raabe, T. (2013) The p21-activated kinase Mbt is a component of the apical protein complex in central brain neuroblasts and controls cell proliferation. Development 140, 1871-1881.
    • Stark, F., Pfannstiel, J., Klaiber, I., Raabe, T. (2011) Protein kinase CK2 links polyamine metabolism to MAKK signalling in Drosophila. Cell. Signal. 23, 876-882.
    • Kress, T.R., Raabe, T., Feller, S.M. (2010) High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cells. Cell. Commun. Signal 8(1):1.
    • Hovhanyan, A., and Raabe, T. (2009) Structural Brain Mutants: Mushroom Body Defect (Mud): A Case Study. J. Neurogenetics 23, 42-47.
    • Fischer, M., Raabe, T., Heisenberg, M., Sendtner, M. (2009) Drosophila RSK negatively regulates bouton number at the neuromuscular junction. Dev. Neurobiol. 69, 212-220.
    • Akten, B., Tangredi, M.M., Jauch, E., Roberts, M.A., Ng, F., Raabe, T., Jackson, R.F. (2009) Ribosomal S6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator. J. Neurosci. 29, 466-475.
    • Mentzel, B., Jauch, E., Raabe, T. (2009) CK2beta interacts with regulates p21-activated kinases in Drosophila. Biochem. Biophys. Res. Comm. 379, 637-642.
    • Menzel, N., Melzer, J., Waschke, J., Lenz, C., Wecklein, H., Lochnit, G., Drenckhahn, D., Raabe, T. (2008) The Drosophila p21-activated kinase Mbt modulates DE-cadherin-mediated cell adhesion by phosphorylation of Armadillo. Biochem. J. 416, 231-241.
    • Menzel, N., Chari, A., Fischer, U., Linder, M., Raabe, T. (2007) A 5´-fluorosulfonylbenzoyladensine-based method to identify physiological substrates of a Drosophila p21-activated kinase. Anal. Biochem. 368, 178-184.
    • Menzel, N., Schneeberger, D., Raabe, T. (2007) The Drosophila p21 activated kinase Mbt regulates the actin cytoskeleton and adherens junctions to control photoreceptor cell morphogenesis. Mech. Dev. 124, 78-90.
    • Izumi, Y., Ohta, N., Hisata, K., Raabe, T., Matsuzaki, F. (2006) Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization. Nature Cell Biol. 8, 586-593.
    • Jauch, E., Wecklein, H., Stark, F., Jauch, M., Raabe, T. (2006) The CK2 transcription unit encodes for functionally non-redundant protein isoforms. Gene 374, 142-152.
    • Gorska-Andrzejak, J., Keller, A., Raabe, T., Kilianek, L., Pyza, E. (2005) Structural daily rhythms in GFP-labelled neurons in the visual system of Drosophila melanogaster. Photochem. Photobiol. Sci. 4, 721-726.
    • Mentzel, B., Raabe, T. (2005) Phylogenetic and structural analysis of the Drosophila melanogaster p21-activated kinase DmPAK3. Gene 349, 25-33.
    • Raabe, T., Clemens-Richter, S., Twardzik, T., Ebert, A., Gramlich, G., Heisenberg, M. (2004) Identification of Mushroom body miniature, a zinc-finger protein implicated in brain development of Drosophila. PNAS 101, 14276-14281.
    • Putz, G., Bertolucci, F., Raabe, T., Zars, T., Heisenberg, M. (2004) The S6KII(rsk) Gene of Drosophila melanogaster Differentially Affects an Operant and a Classical Learning Task. The Journal of Neuroscience 24, 9745-9751. 
    • Akten, B., Jauch, E., Genova, G. K., Kim, E. Y., Edery, I., Raabe, T., Jackson, R. F. (2003) A role for CK2 in the Drosophila circadian oscillator. Nature Neuroscience 6, 251-257. 
    • Schneeberger, D., Raabe, T. (2003). Mbt, a Drosophila PAK protein, combines with D-Cdc42 to regulate photoreceptor cell morphogenesis. Development 130, 427-437. 
    • Scott, E. K., Raabe, T., Luo, L. (2002) Structure of the vertical and horizontal system neurons of the lobula plate in Drosophila. J. Comp. Neurol. 454, 470-481. 
    • Jauch, E., Melzig, J., Brkulj, M., and Raabe, T. (2002) In vivo functional analysis of Drosophila protein kinase casein kinase 2 (CK2) beta-subunit. Gene 298, 29-39.
    • Raabe, T., Rapp, U.R. (2002) KSR-a regulator and scaffold protein of the MAP kinase pathway. Science STKE 136, pe28.
    • Feller, S.M., Wecklein, H., Lewitzky, M., Kibler, E., Raabe, T.  (2002) SH3 domain-mediated binding of the Drk protein to Dos is an important step in signaling of Drosophila receptor tyrosine kinases.. Mech. Dev 116, 129-139.
    • Kerkhoff, E., Simpson, J.C., Leberfinger, C.B., Otto, I.M., Doerks, T., Bork, P., Rapp, U.R., Raabe, T., Pepperkok, R. (2001) The Spir actin organizers are involved in vesicle transport processes. Curr. Biol. 11, 1963-1968.
    • Bausenwein, B.S., Schmidt, M., Mielke, B., Raabe, T. (2000) In vivo functional analysis of the Daughter of Sevenless protein in receptor tyrosine kinase signaling. Mech. Dev. 90, 205-215.
    • Raabe, T. (2000) The Sevenless signaling pathway: variations of a common theme. Biochem. Biophys. Acta 1496, 151-163.
    • Otto, I.M., Raabe, T., Rennefahrt, U.E.E., Bork, P., Rapp, U.R., Kerkhoff, E. (2000) The p150-Spir protein provides a link between c-Jun N-terminal kinase function and actin reorganization. Curr. Biol. 10, 345-348. 
    • Guan, Z., Prado, A., Melzig, J., Heisenberg, M., Nash, H. A., and Raabe, T. (2000). Mushroom body defect, a gene involved in the control of neuroblast proliferation in Drosophila, encodes a coiled-coil protein. Proc Natl Acad Sci USA 97, 8122-8127. 
    • Martin, J. R., Raabe, T., and Heisenberg, M. (1999). Central complex substructures are required for the maintenance of locomotor activity in Drosophila melanogaster. J comp Physiol 185, 277-288.
    • Melzig, J., Rein, K.-H., Schäfer, U., Pfister, H., Jäckle, H., Heisenberg, M., and Raabe, T. (1998). A protein related to p21-activated kinase (PAK) that is involved in neurogenesis in the Drosophila adult central nervous system. Curr. Biol. 8, 1223-1226. 
    • Raabe, T. (1998). Genetic analysis of sevenless tyrosine kinase signaling in Drosophila. In Pawson, A.J., (Ed) Current Topics Microbiology and Immunology, Vol. 228. Berlin, Springer, 343-361.
    • Raabe,T., Riesgo-Escovar,J., Liu,X., Bausenwein,B.S., Deak,P., Maröy,P., and Hafen,E. (1996) DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless ans Ras1 in Drosophila. Cell  85, 911-920. 
    • Herbst,R., Caroll,P.M., Allard,J.D., Schilling,J., Raabe,T., and Simon,T. (1996) Daughter of Sevenless is a substrate of the phosphotyrosine phosphatase corkscrew and functions during sevenless signaling. Cell  85, 899-909.