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    Lehrstuhl für Neurobiologie und Genetik

    The Neuronal Circuit of the Dorsal Circadian Clock Neurons in Drosophila melanogaster

    29.04.2022

    Drosophila’s dorsal clock neurons (DNs) consist of four clusters (DN1as, DN1ps, DN2s, and DN3s). In comparison to the well-characterized lateral clock neurons (LNs), the neuroanatomy and function of the DNs are still not fully understood.

    Drosophila’s dorsal clock neurons (DNs) consist of four clusters (DN1as, DN1ps, DN2s, and DN3s). In comparison to the well-characterized lateral clock neurons (LNs), the neuroanatomy and function of the DNs are still not fully understood. Here, we used the Flybow system, specific split-GAL4 lines, trans-Tango, and the recently published fly connectome (called hemibrain) to describe the morphology of the DNs in greater detail, including their connectivity within the clock network and beyond. We identified two putative novel communication centers of the clock network that may serve as additional communication and input/output centers for the clock neurons and may be of special interest for future experiments.

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    Journal: Forntiers in Physiology
    Autoren: 
    Nils Reinhard1Frank K. Schubert1Enrico Bertolini2, Nicolas Hagedorn1Giulia Manoli1Manabu Sekiguchi3Taishi Yoshii3Dirk Rieger1 and Charlotte Helfrich-Förster1

    DOI: https://doi.org/10.3389/fphys.2022.886432

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