Lehrstuhl für Neurobiologie und Genetik

    Veröffentlichungen des Lehrstuhls ab 2009

    Gruppenfoto gesamter Lehrstuhl


    • Beck, K., Hovhanyan, A., Menegazzi, P., Helfrich-Förster, C., and Raabe, T. (2018) Drosophila RSK Influences the Pace of the Circadian Clock by Negative Regulation of Protein Kinase Shaggy Activity, Frontiers in Molecular Neuroscience 11, 122.
    • Beer, K. (2018) A comparison of the circadian clock of highly social bees (Apis mellifera) and solitary bees (Osmia spec.): Circadian clock development, behavioral rhythms and neuroanatomical characterization of two central clock components (PER and PDF), PhD Thesis, University of Wuerzburg.
    • Beer, K., Kolbe, E., Kahana, N. B., Yayon, N., Weiss, R., Menegazzi, P., Bloch, G., and Helfrich-Förster, C. (2018) Pigment-Dispersing Factor-expressing neurons convey circadian information in the honey bee brain, Open Biology 8, 170224.
    • Bertolini, E., Kistenpfennig, C., Menegazzi, P., Keller, A., Koukidou, M., and Helfrich-Förster, C. (2018) The characterization of the circadian clock in the olive fly Bactrocera oleae (Diptera: Tephritidae) reveals a Drosophila-like organization, Sci Reports 8, 816.
    • Helfrich-Förster, C. (2018) Sleep in Insects, Annual Review of Entomology 63.
    • Kay, J. (2018) The circadian clock of the carpenter ant Camponotus floridanus, PhD Thesis, University of Wuerzburg.
    • Kay, J., Menegazzi, P., Mildner, S., Roces, F., and Helfrich-Förster, C. (2018) The circadian clock of the ant Camponotos floridanus is localized in dorsal and lateral neurons of the brain, in press.
    • Kay, J., Menegazzi, P., Mildner, S., Roces, F., and Helfrich-Förster, C. (2018) The Circadian Clock of the Ant Camponotus floridanus Is Localized in Dorsal and Lateral Neurons of the Brain, Journal of biological rhythms 33, 255--271.
    • Lyutova, R., Pfeuffer, M., Segebarth, D., Habenstein, J., Selcho, M., Wegener, C., Thum, A. S., and Pauls, D. (2018) Reward signaling in a recurrent circuit of dopaminergic neurons and Kenyon cells, bioRxiv.
    • Pauls, D., Blechschmidt, C., Frantzmann, F., el Jundi, B., and Selcho, M. (2018) A comprehensive anatomical map of the peripheral octopaminergic/tyraminergic system of Drosophila melanogaster, bioRxiv.
    • Pilorz, V., Helfrich-Förster, C., and Oster, H. (2018) The role of the circadian clock system in physiology, Pflügers Archiv - European Journal of Physiology.
    • Predel, R., Neupert, S., Derst, C., Reinhardt, K., and Wegener, C. (2018) Neuropeptidomics of the Bed Bug Cimex lectularius, Journal of Proteome Research 17, 440-454.
    • Schlichting, M., Rieger, D., Cusumano, P., Grebler, R., Costa, R., Mazzotta, G., and Helfrich-Förster, C. (2018) Cryptochrome interacts with actin and enhances eye-mediated light sensitivity of the circadian clock in Drosophila melanogaster, Frontiers in Molecular Neuroscience 11, 238.
    • Schubert, F. K., Hagedorn, N., Yoshii, T., Helfrich-Förster, C., and Rieger, D. (2018) Neuroanatomical details of the lateral neurons of Drosophila melanogaster support their functional role in the circadian system, J Comp Neurol 526, 1209-1231.
    • Schubert, F. (2018) The circadian clock network of Drosophila melanogaster, PhD Thesis, University of Wuerzburg.
    • Selcho, M., Mühlbauer, B., Hensgen, R., Shiga, S., Wegener, C., and Yasuyama, K. (2018) Anatomical characterization of PDF-Tri neurons and peptidergic neurons associated with eclosion behavior in Drosophila, Journal of Comparative Neurology, Wiley Online Library.


    • Beer, K., Joschinski, J., Arrazola Sastre, A., Krauss, J., and Helfrich-Förster, C. (2017) A damping circadian clock drives weak oscillations in metabolism and locomotor activity of aphids (Acyrthosiphon pisum), Sci Rep 7, 14906-14906.
    • Benna, C., Helfrich-Förster, C., Rajendran, S., Monticelli, H., Pilati, P., Nitti, D., and Mocellin, S. (2017) Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis, Oncotarget.
    • Berlandi, J., Lin, F. -J., Ambrée, O., Rieger, D., Paulus, W., and Jeibmann, A. (2017) Swing Boat: Inducing and Recording Locomotor Activity in a Drosophila melanogaster Model of Alzheimer’s Disease, Frontiers in Behavioral Neuroscience 11, 159.
    • Frenkel, L., Muraro, N. I., González, A. N. B., Marcora, M. S., Bernabó, G., Hermann-Luibl, C., Romero, J. I., Helfrich-Förster, C., Castaño, E. M., Marino-Busjle, C., Calvo, D. J., and Ceriani, M. F. (2017) Organization of Circadian Behavior Relies on Glycinergic Transmission, Cell Reports 19, 72-85.
    • Fuchikawa, T., Beer, K., Linke-Winnebeck, C., Ben-David, R., Kotowoy, A., Tsang, V. W. K., Warman, G. R., Winnebeck, E. C., Helfrich-Förster, C., and Bloch, G. (2017) Neuronal circadian clock protein oscillations are similar in behaviourally rhythmic forager honeybees and in arrhythmic nurses, Open Biology 7, 170047.
    • Grebler, R., Kistenpfennig, C., Rieger, D., Bentrop, J., Schneuwly, S., Senthilan, P. R., and Helfrich-Förster, C. (2017) Drosophila Rhodopsin 7 can partially replace the structural role of Rhodopsin 1, but not its physiological function, Journal of Comparative Physiology A 1--11.
    • Helfrich-Förster, C. (2017) The Drosophila Clock System. In Biological Timekeeping: Clocks, Rhythms and Behaviour (Kumar, V., Ed.), pp 133-176, Springer India, New Delhi.
    • Kistenpfennig, C., Nakayama, M., Nihara, R., Tomioka, K., Helfrich-Förster, C., and Yoshii, T. (2017) A Tug-of-War between Cryptochrome and the Visual System Allows the Adaptation of Evening Activity to Long Photoperiods in Drosophila melanogaster., Journal of biological rhythms 33, 24-34.
    • Kistenpfennig, C., Grebler, R., Ogueta, M., Hermann-Luibl, C., Schlichting, M., Stanewsky, R., Senthilan, P. R., and Helfrich-Förster, C. (2017) A new Rhodopsin influences light-dependent daily activity patterns of fruit flies, Journal of biological rhythms 32, 406--422.
    • Martelli, C., Pech, U., Kobbenbring, S., Pauls, D., Bahl, B., Sommer, M. V., Pooryasin, A., Barth, J., Arias, C. W. P., Vassiliou, C., Luna, A. J. F., Poppinga, H., Richter, F. G., Wegener, C., Fiala, A., and Riemensperger, T. (2017) SIFamide Translates Hunger Signals into Appetitive and Feeding Behavior in Drosophila, Cell Reports 20, 464 - 478.
    • Menegazzi, P., Benetta, E. D., Beauchamp, M., Schlichting, M., Steffan-Dewenter, I., and Helfrich-Förster, C. (2017) Adaptation of circadian neuronal network to photoperiod in high-latitude European Drosophilids, CURR BIOL 27, 833-839.
    • Ruf, F. (2017) The circadian regulation of eclosion in Drosophila melanogaster.
    • Ruf, F., Fraunholz, M., Öchsner, K., Kaderschabek, J., and Wegener, C. (2017) WEclMon--A simple and robust camera-based system to monitor Drosophila eclosion under optogenetic manipulation and natural conditions, PloS one 12, e0180238.
    • Schmitt, F., Vanselow, J. T., Schlosser, A., Wegener, C., and Rössler, W. (2017) Neuropeptides in the desert ant Cataglyphis fortis: Mass spectrometric analysis, localization, and age-related changes, J Comp Neurol 525, 901--918.
    • Selcho, M., Millán, C., Palacios-Muñoz, A., Ruf, F., Ubillo, L., Chen, J., Bergmann, G., Ito, C., Silva, V., Wegener, C., and others,. (2017) Central and peripheral clocks are coupled by a neuropeptide pathway in Drosophila, Nature Communications 8, 8:15563.
    • Widmann, A., Eichler, K., Selcho, M., Thum, A. S., and Pauls, D. (2017) Odor-taste Learning in Drosophila Larvae, Journal of Insect Physiology.
    • Zotzmann, S., Steinbrink, A., Schleich, K., Frantzmann, F., Xoumpholphakdy, C., Spaeth, M., Moro, C. V., Mavingui, P., and Klimpel, S. (2017) Bacterial diversity of cosmopolitan Culex pipiens and invasive Aedes japonicus from Germany, Parasitology Research 116, 1899--1906.


    • Beer, K., Steffan-Dewenter, I., Härtel, S., and Helfrich-Förster, C. (2016) A new device for monitoring individual activity rhythms of honey bees reveals critical effects of the social environment on behavior, J Comp Physiol A 202, 555-565.
    • Benoit, J. B., Adelman, Z. N., Reinhardt, K., Dolan, A., Poelchau, M., Jennings, E. C., Szuter, E. M., Hagan, R. W., Gujar, H., Shukla, J. N., Menegazzi, P., Wegener, C., and Peschel, N. et al. (2016) Unique features of a global human ectoparasite identified through sequencing of the bed bug genome, Nat Commun 7.
    • Chen, J., Reiher, W., Hermann-Luibl, C., Sellami, A., Cognigni, P., Kondo, S., Helfrich-Förster, C., Veenstra, J. A., and Wegener, C. (2016) Allatostatin a signalling in Drosophila regulates feeding and sleep and is modulated by PDF, PLOS Genet 12, e1006346.
    • Eck, S. (2016) The impact of thermogenetic depolarizations of specific clock neurons on Drosophila melanogaster’s ciecadian clock., PhD Thesis, University of Wuerzburg.
    • Eck, S., Helfrich-Förster, C., and Rieger, D. (2016) The timed depolarization of morning and evening oscillators phase shifts the circadian clock of Drosophila, J Biol Rhythms 31, 428-442.
    • Fischer, R., Helfrich-Förster, C., and Peschel, N. (2016) GSK-3 Beta does not stabilize cryptochrome in the circadian clock of Drosophila, PLOS ONE 11, 1-17.
    • Joschinski, J., Beer, K., Helfrich-Förster, C., and Krauss, J. (2016) Pea aphids (Hemiptera: Aphididae) have diurnal rhythms when raised independently of a host plant, J Insect Sci 16, 31.
    • Koch, C. E., Bartlang, M. S., Kiehn, J. T., Lucke, L., Naujokat, N., Helfrich-Förster, C., Reber, S. O., and Oster, H. (2016) Time-of-day-dependent adaptation of the HPA axis to predictable social defeat stress, J Endocrinol 231, 209-221.
    • Mena, W., Diegelmann, S., Wegener, C., and Ewer, J. (2016) Stereotyped responses of Drosophila peptidergic neuronal ensemble depend on downstream neuromodulators, eLife 5, e19686.
    • Schlichting, M., Menegazzi, P., Lelito, K. R., Yao, Z., Buhl, E., Dalla Benetta, E., Bahle, A., Denike, J., Hodge, J. J., Helfrich-Förster, C., and others,. (2016) A neural network underlying circadian entrainment and photoperiodic adjustment of sleep and activity in Drosophila, J Neurosci 36, 9084-9096.
    • Senthilan, P. R., and Helfrich-Förster, C. (2016) Rhodopsin 7--The unusual Rhodopsin in Drosophila, PeerJ 4, e2427.
    • Vaze, K. M., and Helfrich-Förster, C. (2016) Drosophila ezoana uses an hour-glass or highly damped circadian clock for measuring night length and inducing diapause, Physiol Entomol 41, 378-389.
    • Widmann, A., Artinger, M., Biesinger, L., Boepple, K., Peters, C., Schlechter, J., Selcho, M., and Thum, A. S. (2016) Genetic Dissection of Aversive Associative Olfactory Learning and Memory in Drosophila Larvae, PLOS Genetics 12, 1-32.
    • Yoshii, T., Hermann-Luibl, C., and Helfrich-Förster, C. (2016) Circadian light-input pathways in Drosophila, Commun Integr Biol 9, e1102805.


    • Ahmed, Z., Mayr, M., Zeeshan, S., Dandekar, T., Mueller, M. J., and Fekete, A. (2015) Lipid-Pro: a computational lipid identification solution for untargeted lipidomics on data-independent acquisition tandem mass spectrometry platforms, Bioinformatics 31, 1150-1153.
    • Bartlang, M. S., Oster, H., and Helfrich-Förster, C. (2015) Repeated Psychosocial Stress at Night Affects the Circadian Activity Rhythm of Male Mice, J Biol Rhythms 30, 228-241.
    • Chouhan, N.  S., Wolf, R., Helfrich-Förster, C., and Heisenberg, M. (2015) Flies remember the time of day, CURR BIOL 25, 1619-1624.
    • Gellerer, A., Franke, A., Neupert, S., Predel, R., Zhou, X., Liu, S., Reiher, W., Wegener, C., and Homberg, U. (2015) Identification and distribution of SIFamide in the nervous system of the desert locust Schistocerca gregaria, J Comp Neurol 523, 108-125.
    • Grebler, R. (2015) Investigation of Rhodopsin 7 and Cryptochrome in Drosophila melanogaster vision, PhD Thesis, University of Wuerzburg.
    • Hermann-Luibl, C., and Helfrich-Förster, C. (2015) Clock network in Drosophila, Curr Opin Insect Sci 7, 65-70.
    • Johnsson, A., Helfrich-Förster, C., and Engelmann, W. (2015) How light resets circadian clocks. In Photobiology, pp 243-297, Springer.
    • Kmoch, S., Majewski, J., Ramamurthy, V., Cao, S., Fahiminiya, S., Ren, H., MacDonald, I. M., Lopez, I., Sun, V., Keser, V., Khan, A., Stránecký, V., Hartmannová, H., Přistoupilová, A., Hodaňová, K., Piherová, L., Kuchař, L., Baxová, A., Chen, R., Barsottini, O. G., Pyle, A., Griffin, H., Splitt, M., Sallum, J., Tolmie, J. L., Sampson, J. R., Chinnery, P., Canada, C. 4R., Banin, E., Sharon, D., Dutta, S., Grebler, R., Helfrich-Foerster, C., Pedroso, J. L., Kretzschmar, D., Cayouette, M., and Koenekoop, R. K. (2015) Mutations in PNPLA6 are linked to photoreceptor degeneration and various forms of childhood blindness, Nat Commun 6, 5614-5614.
    • Pauls, D., von Essen, A., Lyutova, R., van Giesen, L., Rosner, R., Wegener, C., and Sprecher, S. G. (2015) Potency of transgenic effectors for neurogenetic manipulation in Drosophila larvae, Genetics 199, 25-37.
    • Rohwedder, A., Selcho, M., Chassot, B., and Thum, A. S. (2015) Neuropeptide F neurons modulate sugar reward during associative olfactory learning of Drosophila larvae, J Comp Neurol 523, 2637-2664.
    • Schlichting, M. (2015) Light entrainment of the circadian clock: the importance of the visual system for adjusting Drosophila melanogaster’s activity pattern, PhD Thesis, University of Wuerzburg.
    • Schlichting, M., Grebler, R., Menegazzi, P., and Helfrich-Förster, C. (2015) Twilight dominates over moonlight in adjusting Drosophila’s activity pattern, J Biol Rhythms 30, 117-128.
    • Schlichting, M., and Helfrich-Förster, C. (2015) Chapter Five - Photic Entrainment in Drosophila Assessed by Locomotor Activity Recordings. In Circadian Rhythms and Biological Clocks, Part B (Sehgal, A., Ed.), pp 105-123.
    • Schlichting, M., and Helfrich-Förster, C. (2015) Photic entrainment in Drosophila assessed by locomotor activity recordings. In Methods Enzymol, pp 105-123.
    • Schlichting, M., Menegazzi, P., and Helfrich-Förster, C. (2015) Normal vision can compensate for the loss of the circadian clock, Proc R Soc Lond B: Biol Sci 282, 20151846.
    • Schmitt, F., Vanselow, J. T., Schlosser, A., Kahnt, J., Rössler, W., and Wegener, C. (2015) Neuropeptidomics of the carpenter ant Camponotus floridanus, J Proteome Res 14, 1504-1514.
    • Selcho, M., and Wegener, C. (2015) Immunofluorescence and Genetic Fluorescent Labeling Techniques in the Drosophila Nervous System, Immunocytochemistry and Related Techniques 39-62.
    • Wegener, C., and Veenstra, J. A. (2015) Chemical identity, function and regulation of enteroendocrine peptides in insects, Curr Opin Insect Sci 11, 8-13.
    • Yoshii, T., Hermann-Luibl, C., Kistenpfennig, C., Schmid, B., Tomioka, K., and Helfrich-Förster, C. (2015) Cryptochrome-Dependent and -Independent Circadian Entrainment Circuits in Drosophila, J Neurosci 35, 6131--6141.


    • Ahmed, Z. (2014) Ant-App-Database towards neural, behavioral research on deserts ants and approximate solar estimations, Neuroinformatics 93.
    • Ahmed, Z., Zeeshan, S., and Dandekar, T. (2014) Developing sustainable software solutions for bioinformatics by the “Butterfly” paradigm, F1000Research, Faculty of 1000 Ltd 3.
    • Ahmed, Z., Zeeshan, S., Fleischmann, P., Rössler, W., and Dandekar, T. (2014) Ant-App-DB: a smart solution for monitoring arthropods activities, experimental data management and solar calculations without GPS in behavioral field studies, F1000Research, Faculty of 1000 Ltd 3.
    • Ahmed, Z., Zeeshan, S., Huber, C., Hensel, M., Schomburg, D., Münch, R., Eylert, E., Eisenreich, W., and Dandekar, T. (2014) ‘Isotopo’a database application for facile analysis and management of mass isotopomer data, Database, Oxford University Press 2014, bau077.
    • Bartlang, M. S., Savelyev, S. A., Johansson, A. -S., Reber, S. O., Helfrich-Förster, C., and Lundkvist, G. B. S. (2014) Repeated psychosocial stress at night, but not day, affects the central molecular clock, Chronobiol Int 31, 996-1007.
    • Dandekar, T., Fieselmann, A., Majeed, S., and Ahmed, Z. (2014) Software applications toward quantitative metabolic flux analysis and modeling, Briefings in bioinformatics, Oxford Univ Press 15, 91-107.
    • Dusik, V., Senthilan, P. R., Mentzel, B., Hartlieb, H., Wülbeck, C., Yoshii, T., Raabe, T., and Helfrich-Förster, C. (2014) The MAP kinase p38 is part of Drosophila melanogaster's circadian clock, PLoS genetics 10, e1004565.
    • Helfrich-Förster, C. (2014) From neurogenetic studies in the fly brain to a concept in circadian biology, J Neurogenet 28, 329-347.
    • Hermann-Luibl, C., Yoshii, T., Senthilan, P. R., Dircksen, H., and Helfrich-Förster, C. (2014) The ion transport peptide is a new functional clock neuropeptide in the fruit fly Drosophila melanogaster, J Neurosci 34, 9522-9536.
    • Pauls, D., Chen, J., Reiher, W., Vanselow, J. T., Schlosser, A., Kahnt, J., and Wegener, C. (2014) Peptidomics and processing of regulatory peptides in the fruit fly Drosophila, EuPA Open Proteomics 3, 114-127.
    • Schlichting, M., Grebler, R., Peschel, N., Yoshii, T., and Helfrich-Förster, C. (2014) Moonlight detection by Drosophila's endogenous clock depends on multiple photopigments in the compound eyes, J Biol Rhythms 29, 75-86.
    • Selcho, M. *, Pauls, D. *, Huser, A., Stocker, R. F., and Thum, A. S. (2014) Characterization of the octopaminergic and tyraminergic neurons in the central brain of Drosophila larvae, J Comp Neurol 522, 3485-3500.
    • Wegener, C. (2014) Peptide profiling of the retrocerebral complex and identification of an adipokinetic hormone and short neuropeptide F peptides in diapausing and non-diapausing cherry fruit flies Rhagoletis cerasi (Diptera: Tephritidae), Mitt Dtsch Ges Allg Angew Entomol 19, 265-268.


    • Ahmed, Z., and Helfrich-Förster, C. (2013) DroLIGHT: real time embedded system towards endogenous clock synchronization of drosophila. In Front Neuroinform Conference Abstract: Neuroinformatics.
    • Ahmed, Z., and Helfrich-Förster, C. (2013) DroLIGHT-2: real time embedded and data management system for synchronizing circadian clock to the light-dark cycles, Recent Patents on Computer Science 6, 191-205.
    • Ahmed, Z., Helfrich-Förster, C., and Dandekar, T. (2013) Integrating Formal UML Designs and HCI Patterns with Spiral SDLC in DroLIGHT Implementation, Recent Patents on Computer Science 6, 85-98.
    • Gmeiner, F., Kołodziejczyk, A., Yoshii, T., Rieger, D., Nässel, D. R., and Helfrich-Förster, C. (2013) GABA(B) receptors play an essential role in maintaining sleep during the second half of the night in Drosophila melanogaster, J Exp Biol 216, 3837-3843.
    • Hermann, C., Saccon, R., Senthilan, P. R., Domnik, L., Dircksen, H., Yoshii, T., and Helfrich-Förster, C. (2013) The circadian clock network in the brain of different Drosophila species, J Comp Neurol 521, 367-388.
    • Karsai, G., Pollák, E., Wacker, M., Vömel, M., Selcho, M., Berta, G., Nachman, R. J., Isaac, R. E., Molnár, L., and Wegener, C. (2013) Diverse in-and output polarities and high complexity of local synaptic and non-synaptic signaling within a chemically defined class of peptidergic Drosophila neurons, Front Neural Circuits 7, 127.
    • Kronfeld-Schor, N., Dominoni, D., de la Iglesia, H., Levy, O., Herzog, E. D., Dayan, T., and Helfrich-Forster, C. (2013) Chronobiology by moonlight, Proc R Soc Lond B: Biol Sci 280, 20123088.
    • Mazzotta, G., Rossi, A., Leonardi, E., Mason, M., Bertolucci, C., Caccin, L., Spolaore, B., Martin, A. J. M., Schlichting, M., Grebler, R., Helfrich-Förster, C., and others,. (2013) Fly cryptochrome and the visual system, Proc Natl Acad Sci 110, 6163-6168.
    • Menegazzi, P., Vanin, S., Yoshii, T., Rieger, D., Hermann, C., Dusik, V., Kyriacou, C. P., Helfrich-Förster, C., and Costa, R. (2013) Drosophila clock neurons under natural conditions, J Biol Rhythms 28, 3-14.
    • Redondo, B. B., Bunz, M., Halder, P., Sadanandappa, M. K., Mühlbauer, B., Erwin, F., Hofbauer, A., Rodrigues, V., VijayRaghavan, K., Ramaswami, M., Rieger, D., Wegener, C., Helfrich-Förster, C., and Buchner, E. (2013) Identification and structural characterization of interneurons of the Drosophila brain by monoclonal antibodies of the Würzburg Hybridoma Library, PLOS ONE 8, 1-9.
    • Vaze, K. M., Nikhil, K. L., and Sharma, V. K. (2013) Genetic architecture underlying morning and evening circadian phenotypes in fruit flies Drosophila melanogaster, Heredity 111, 265-274.
    • Vaze, K. M., and Sharma, V. K. (2013) On the adaptive significance of circadian clocks for their owners, Chronobiol Int 30, 413-433.


    • Bartlang, M. S., Neumann, I. D., Slattery, D. A., Uschold-Schmidt, N., Kraus, D., Helfrich-Förster, C., and Reber, S. O. (2012) Time matters: pathological effects of repeated psychosocial stress during the active, but not inactive, phase of male mice, J Endocrinol 215, 425-437.
    • Bywalez, W., Menegazzi, P., Rieger, D., Schmid, B., Helfrich-Förster, C., and Yoshii, T. (2012) The dual-oscillator system of Drosophila melanogaster under natural-like temperature cycles, Chronobiol Int 29, 395-407.
    • Hermann, C., Yoshii, T., Dusik, V., and Helfrich-Förster, C. (2012) Neuropeptide F immunoreactive clock neurons modify evening locomotor activity and free-running period in Drosophila melanogaster, J Comp Neurol 520, 970-987.
    • Huser, A., Rohwedder, A., Apostolopoulou, A. A., Widmann, A., Pfitzenmaier, J. E., Maiolo, E. M., Selcho, M., Pauls, D., von Essen, A., Gupta, T., and others,. (2012) The serotonergic central nervous system of the Drosophila larva: anatomy and behavioral function, PLoS One 7, e47518.
    • Kauranen, H., Menegazzi, P., Costa, R., Helfrich-Förster, C., Kankainen, A., and Hoikkala, A. (2012) Flies in the north: Locomotor behavior and clock neuron organization of Drosophila montana, J Biol Rhythms 27, 377-387.
    • Kistenpfennig, C., Hirsh, J., Yoshii, T., and Helfrich-Förster, C. (2012) Phase-shifting the fruit fly clock without cryptochrome, J Biol Rhythms 27, 117-125.
    • Menegazzi, P., Yoshii, T., and Helfrich-Förster, C. (2012) Laboratory versus Nature The Two Sides of the Drosophila Circadian Clock, J Biol Rhythms 27, 433-442.
    • Rieger, D., Peschel, N., Dusik, V., Glotz, S., and Helfrich-Förster, C. (2012) The ability to entrain to long photoperiods differs between 3 Drosophila melanogaster wild-type strains and is modified by twilight simulation, J Biol Rhythms 27, 37-47.
    • Selcho, M. *, Pauls, D. *, el Jundi, B., Stocker, R. F., and Thum, A. S. (2012) The Role of octopamine and tyramine in Drosophila larval locomotion, J Comp Neurol 520, 3764-3785.
    • Sellami, A., Wegener, C., and Veenstra, J. A. (2012) Functional significance of the copper transporter ATP7 in peptidergic neurons and endocrine cells in Drosophila melanogaster, Letters 586, 3633-3638.
    • Senthilan, P.  R., Piepenbrock, D., Ovezmyradov, G., Nadrowski, B., Bechstedt, S., Pauls, S., Winkler, M., Möbius, W., Howard, J., and Göpfert, M.  C. (2012) Drosophila auditory organ genes and genetic hearing defects, Cell 150, 1042-1054.
    • Umezaki, Y., Yoshii, T., Kawaguchi, T., Helfrich-Förster, C., and Tomioka, K. (2012) Pigment-dispersing factor is involved in age-dependent rhythm changes in Drosophila melanogaster, J Biol Rhythms 27, 423--432.
    • Vanin, S., Bhutani, S., Montelli, S., Menegazzi, P., Green, E. W., Pegoraro, M., Sandrelli, F., Costa, R., and Kyriacou, C. P. (2012) Unexpected features of Drosophila circadian behavioural rhythms under natural conditions, Nature 484, 371-375.
    • Vaze, K. M., Kannan, N. N., Abhilash, L., and Sharma, V. K. (2012) Chronotype differences in Drosophila are enhanced by semi-natural conditions, Naturwissenschaften 99, 967-971.
    • Vaze, K. M., and Sharma, V. K. (2012) Early-and late-emerging Drosophila melanogaster fruit flies differ in their sensitivity to light during morning and evening, Chronobiol Int 29, 674-682.
    • Vieira, J., Jones, A. R., Danon, A., Sakuma, M., Hoang, N., Robles, D., Tait, S., Heyes, D. J., Picot, M., Yoshii, T., Helfrich-Förster, C., and others,. (2012) Human cryptochrome-1 confers light independent biological activity in transgenic Drosophila correlated with flavin radical stability, PLoS One 7, e31867.
    • Yoshii, T., Rieger, D., and Helfrich-Förster, C. (2012) Two clocks in the brain. In Progress in Brain Research, pp 59-82, Elsevier BV.
    • Yoshii, T., Rieger, D., and Helfrich-Förster, C. (2012) Chapter 4 - Two clocks in the brain: An update of the morning and evening oscillator model in Drosophila. In The Neurobiology of Circadian Timing (Andries Kalsbeek, M. M., and Foster, R. G., Eds.), pp 59-82.
    • Zoephel, J., Reiher, W., Rexer, K. -H., Kahnt, J., and Wegener, C. (2012) Peptidomics of the agriculturally damaging larval stage of the cabbage root fly Delia radicum (Diptera: Anthomyiidae), PloS one 7, e41543.


    • Helfrich-Förster, C., Nitabach, M. N., and Holmes, T. C. (2011) Insect circadian clock outputs, Essays Biochem 49, 87-101.
    • Nässel, D. R., and Wegener, C. (2011) A comparative review of short and long neuropeptide F signaling in invertebrates: Any similarities to vertebrate neuropeptide Y signaling?, Peptides 32, 1335-1355.
    • Peschel, N., and Helfrich-Förster, C. (2011) Setting the clock--by nature: circadian rhythm in the fruitfly Drosophila melanogaster, FEBS letters 585, 1435-1442.
    • Reiher, W., Shirras, C., Kahnt, J., Baumeister, S., Isaac, R. E., and Wegener, C. (2011) Peptidomics and Peptide Hormone Processing in the Drosophila Midgut, J Proteome Res 10, 1881-1892.
    • Schleyer, M., Saumweber, T., Nahrendorf, W., Fischer, B., von Alpen, D., Pauls, D., Thum, A., and Gerber, B. (2011) A behavior-based circuit model of how outcome expectations organize learned behavior in larval Drosophila, Learn Mem 18, 639-653.
    • Schmid, B., Helfrich-Förster, C., and Yoshii, T. (2011) A new ImageJ plug-in “ActogramJ” for chronobiological analyses, J Biol Rhythms 26, 464-467.
    • Thum, A. S., Leisibach, B., Gendre, N., Selcho, M., and Stocker, R. F. (2011) Diversity, variability, and suboesophageal connectivity of antennal lobe neurons in D. melanogaster larvae, The Journal of Comparative Neurology, Wiley Subscription Services, Inc., A Wiley Company 519, 3415--3432.
    • von Essen, A. M. H. J., Pauls, D., Thum, A. S., and Sprecher, S. G. (2011) Capacity of visual classical conditioning in Drosophila larvae., Behav Neurosci 125, 921.
    • Wegener, C., Herbert, H., Kahnt, J., Bender, M., and Rhea, J. M. (2011) Deficiency of prohormone convertase dPC2 (AMONTILLADO) results in impaired production of bioactive neuropeptide hormones in Drosophila, J Neurochem 118, 581-595.


    • Benna, C., Bonaccorsi, S., Wülbeck, C., Helfrich-Förster, C., Gatti, M., Kyriacou, C. P., Costa, R., and Sandrelli, F. (2010) Drosophila timeless2 is required for chromosome stability and circadian photoreception, CURR BIOL 20, 346-352.
    • Helfrich-Förster, C. (2010) Das neuronale Netzwerk der Inneren Uhr, Neuroforum 16, 151.
    • Pauls, D. *, Pfitzenmaier, J. E. R. *, Krebs-Wheaton, R., Selcho, M., Stocker, R. F., and Thum, A. S. (2010) Electric shock-induced associative olfactory learning in Drosophila larvae, Chem Senses 35, 335-346.
    • Pauls, D. *, Selcho, M. *, Gendre, N., Stocker, R. F., and Thum, A. S. (2010) Drosophila larvae establish appetitive olfactory memories via mushroom body neurons of embryonic origin, J Neurosci 30, 10655-10666.
    • Rhea, J. M., Wegener, C., and Bender, M. (2010) The proprotein convertase encoded by amontillado (amon) is required in Drosophila corpora cardiaca endocrine cells producing the glucose regulatory hormone AKH, PLoS Genet 6, e1000967.
    • Ritz, T., Yoshii, T., Helfrich-Förster, C., and Ahmad, M. (2010) Cryptochrome: A photoreceptor with the properties of a magnetoreceptor?, Commun Integr Biol 3, 24-27.
    • Schachtner, J., Wegener, C., Neupert, S., and Predel, R. (2010) Direct peptide profiling of brain tissue by MALDI-TOF mass spectrometry., Methods Mol Biol 615, 129-135.
    • Sidyelyeva, G., Wegener, C., Schoenfeld, B. P., Bell, A. J., Baker, N. E., McBride, S. M. J., and Fricker, L. D. (2010) Individual carboxypeptidase D domains have both redundant and unique functions in Drosophila development and behavior, Cell Mol Life Sci 67, 2991-3004.
    • Wegener, C., Neupert, S., and Predel, R. (2010) Direct MALDI-TOF Mass Spectrometric Peptide Profiling of Neuroendocrine Tissue of Drosophila. In Peptidomics: Methods and Protocols (Soloviev, M., Ed.), pp 117-127.
    • Yoshii, T., Hermann, C., and Helfrich-Förster, C. (2010) Cryptochrome-positive and-negative clock neurons in Drosophila entrain differentially to light and temperature, J Biol Rhythms 25, 387-398.


    • Busch, S., Selcho, M., Ito, K., and Tanimoto, H. (2009) A map of octopaminergic neurons in the Drosophila brain, J Comp Neurol 513, 643-667.
    • Helfrich-Förster, C. (2009) Does the morning and evening oscillator model fit better for flies or mice?, J Biol Rhythms 24, 259-270.
    • Helfrich-Förster, C. (2009) Neuropeptide PDF plays multiple roles in the circadian clock of Drosophila melanogaster, Sleep Biol Rhythms 7, 130-143.
    • Helfrich-Förster, C. (2009) Macht die innere Uhr “mondsüchtig”?, BIOspektrum 5, 491-492.
    • Helfrich-Förster, C., Yoshii, T., Vanin, S., and Costa, R. (2009) The role of PDF in the circadian clock, Sleep Biol Rhythms 7, 130-143.
    • Johard, H. A. D., Yoishii, T., Dircksen, H., Cusumano, P., Rouyer, F., Helfrich-Förster, C., and Nässel, D. R. (2009) Peptidergic clock neurons in Drosophila: ion transport peptide and short neuropeptide F in subsets of dorsal and ventral lateral neurons, J Comp Neurol 516, 59-73.
    • Kempinger, L., Dittmann, R., Rieger, D., and Helfrich-Förster, C. (2009) The nocturnal activity of fruit flies exposed to artificial moonlight is partly caused by direct light effects on the activity level that bypass the endogenous clock, Chronobiol Int 26, 151-166.
    • Lu, Q., Senthilan, P. R., Effertz, T., Nadrowski, B., and Göpfert, M. C. (2009) Using Drosophila for studying fundamental processes in hearing, Integr Comp Biol 49, 674-680.
    • Rieger, D., Wülbeck, C., Rouyer, F., and Helfrich-Förster, C. (2009) Period gene expression in four neurons is sufficient for rhythmic activity of Drosophila melanogaster under dim light conditions, J Biol Rhythms 24, 271-282.
    • Selcho, M. *, Pauls, D. *, Han, K. -A., Stocker, R. F., and Thum, A. S. (2009) The role of dopamine in Drosophila larval classical olfactory conditioning, PLoS ONE 4, e5897.
    • Wülbeck, C., Grieshaber, E., and Helfrich-Förster, C. (2009) Blocking endocytosis in Drosophila's circadian pacemaker neurons interferes with the endogenous clock in a PDF-dependent way, Chronobiol Int 26, 1307-1322.
    • Yoshii, T., Ahmad, M., and Helfrich-Förster, C. (2009) Cryptochrome mediates light-dependent magnetosensitivity of Drosophila's circadian clock, PLoS Biol 7, e1000086.
    • Yoshii, T., Vanin, S., Costa, R., and Helfrich-Förster, C. (2009) Synergic entrainment of Drosophila’s circadian clock by light and temperature, J Biol Rhythms 24, 452-464.
    • Yoshii, T., Wülbeck, C., Sehadova, H., Veleri, S., Bichler, D., Stanewsky, R., and Helfrich-Förster, C. (2009) The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clock, J Neurosci 29, 2597-2610.

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