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CHAIR OF DEVELOPMENTAL BIOCHEMISTRY
Advanced research practical courses are mainly offered to students of the Biomedicine and Biochemistry section

With the CRISPR/Cas9-system you can modify the genome of human kidney cells or murine embryonic stem cells in a specific and precise way. The impact of this introduced mutation on the cells’ differentiation potential can then be investigated with a plethora of biochemical methods. For instance, you can analyze the expression of specific genes with quantitative real-time PCR or Western Blot.

Furthermore, through in vitro cultures of human Wilms tumor cells and their genome sequencing, you can help to contribute to a better understanding of this disease and thus, to finding effective treatments in the future.

Selection of topics
  • Cloning of a homologous recombination vector to introduce an inducible tumor-specific duplication of  BCOR
  • Differentiation alterations of Embryoid Bodies after the C-terminal deletion in the BCOR gene
Contact

Chair of Developmental Biochemistry
Am Hubland
97074 Würzburg

Phone: +49 931 31-84160
Fax: +49 931 31-87038
Email

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Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Julius-von-Sachs-Platz 2 Fabrikschleichach Hubland Süd, Geb. B2 Campus Medizin