Chair of Pharmaceutical Biology


Publikationen Prof. Dr. Dr. M.J. Müller


Amatobi KM, Ozbek-Unal AG, Schäbler S, Deppisch P, Helfrich-Förster C, Mueller MJ, Wegener C, Fekete A. (2023) The circadian clock is required for rhythmic lipid transport in Drosophila in interaction with diet and photic condition.
J. Lipid Res. 100417. doi: 10.1016/j.jlr.2023.100417.

Reichelt, N, Korte, A, Krischke, M, Mueller, MJ, Maag, D (2023) Natural variation of warm-temperature-induced raffinose accumulation identifies TREHALSOSE-6-PHOSPHATE SYNTHASE 1 as a modulator of thermotolerance.
Plant Cell Environ. 1-13.

Korte P, Unzner A, Damm T, Berger S, Krischke M, Mueller MJ (2023) High triacylglycerol turnover is required for efficient opening of stomata during heat stress in Arabidopsis.
Plant J. 115: 81-96., DOI: 10.1111/tpj.16210.

Graus D, Li K, Rathje JM, Ding M, Krischke M, Müller MJ, Cuin TA, Al-Rasheid KAS, Scherzer S, Marten I, Konrad KR, Hedrich R. (2023) Tobacco leaf tissue rapidly detoxifies direct salt loads without activation of calcium and SOS signaling.
New Phytol. 237: 217-231. doi: 10.1111/nph.18501.

Steiner T, Zachary M, Bauer S, Müller MJ, Krischke M, Radziej S, Klepsch M, Huettel B, Eisenreich W, Rudel T, Beier D. (2023) Central Role of Sibling Small RNAs NgncR_162 and NgncR_163 in Main Metabolic Pathways of Neisseria gonorrhoeae.
mBio 14: e0309322. doi: 10.1128/mbio.03093-22.


Schilcher F, Hilsmann L, Ankenbrand M, Krischke M, Mueller MJ, Steffan-Dewenter I, Scheiner R (2022) Honeybees are buffered against undernourishment during larval stages. Frontiers in Insect Science, 18 November 2022, Volume 2 – 2022

Lambour B, Glenz R, Forner C, Krischke M, Mueller MJ, Fekete A, Waller F. (2022) Sphingolipid Long-Chain Base Phosphate Degradation Can Be a Rate-Limiting Step in Long-Chain Base Homeostasis.
Front. Plant Sci., 13: 911073. doi: 10.3389/fpls.2022.911073.

Henninger M, Pedrotti L, Krischke M, Draken J, Wildenhain T, Fekete A, Rolland F, Müller MJ, Fröschel C, Weiste C, Dröge-Laser W. (2022) The evolutionarily conserved kinase SnRK1 orchestrates resource mobilization during Arabidopsis seedling establishment.
Plant Cell, 34: 616-632. doi: 10.1093/plcell/koab270.

Bru P, Steen CJ, Park S, Amstutz CL, Sylak-Glassman EJ, Lam L, Fekete A, Mueller MJ, Longoni F, Fleming GR, Niyogi KK, Malnoë A. (2022) The major trimeric antenna complexes serve as a site for qH-energy dissipation in plants.
J. Biol. Chem. 298: 102519. doi: 10.1016/j.jbc.2022.102519.

Glenz R, Kaiping A, Göpfert D, Weber H, Lambour B, Sylvester M, Fröschel C, Mueller MJ, Osman M, Waller F. (2022) The major plant sphingolipid long chain base phytosphingosine inhibits growth of bacterial and fungal plant pathogens.
Sci. Rep. 12: 1081. doi: 10.1038/s41598-022-05083-4.

Schilcher F, Hilsmann L, Rauscher L, Değirmenci L, Krischke M, Krischke B, Ankenbrand M, Rutschmann B, Mueller MJ, Steffan-Dewenter I, Scheiner R. (2022) In Vitro Rearing Changes Social Task Performance and Physiology in Honeybees.
Insects 13: 4. doi: 10.3390/insects13010004.


Muralidhara P, Weiste C, Collani S, Krischke M, Kreisz P, Draken J, Feil R, Mair A, Teige M, Müller MJ, Schmid M, Becker D, Lunn JE, Rolland F, Hanson J, Dröge-Laser W. (2021) Perturbations in plant energy homeostasis prime lateral root initiation via SnRK1-bZIP63-ARF19 signaling.
Proc. Natl. Acad. Sci USA 118: e2106961118. doi: 10.1073/pnas.2106961118.

Schieferle S, Tappe B, Korte P, Mueller MJ, Berger S. (2021) Pathogens and elicitors induce local and systemic changes in triacylglycerol metabolism in roots and in leaves of Arabidopsis thaliana.
Biology 10: 920 doi: 10.3390/biology10090920

Pauls D, Selcho M, Räderscheidt J, Amatobi KM, Fekete A, Krischke M, Hermann-Luibl C, Ozbek-Unal AG, Ehmann N, Itskov PM, Kittel RJ, Helfrich-Förster C, Kühnlein RP, Mueller MJ, Wegener C. (2021) Endocrine signals fine-tune daily activity patterns in Drosophila.
Curr. Biol. 31: 4076 – 4087. doi: 10.1016/j.cub.2021.07.002.

Karimi SM, Freund M, Wager BM, Knoblauch M, Fromm J, Müller H, Ache P, Krischke M, Mueller MJ, Müller T, Dittrich M, Geilfus CM, Alfarhan AH, Hedrich R, Deeken R. (2021) Under salt stress guard cells rewire ion transport and abscisic acid (ABA) signaling.
New Phytol. In press. doi: 10.1111/nph.17376

Zhou Y, Ding M, Gao S, Yu-Strzelczyk J, Krischke M, Duan X, Leide J, Riederer M, Mueller MJ, Hedrich R, Konrad KR, Nagel G. (2021) Optogenetic control of plant growth by a microbial rhodopsin.
Nat Plants 7:144-151. doi: 10.1038/s41477-021-00853-w

Koschmieder J, Wüst F, Schaub P, Álvarez D, Trautmann D, Krischke M, Rustenholz C, Mano J, Mueller MJ, Bartels D, Hugueney P, Beyer P, Welsch R. (2021) Plant apocarotenoid metabolism utilizes defense mechanisms against reactive carbonyl species and xenobiotics.
Plant Physiol. 185: 331-251. doi: 10.1093/plphys/kiaa033


Vikuk V, Fuchs B, Krischke M, Mueller MJ, Rueb S, Krauss J (2020) Alkaloid concentrations of Lolium perenne infected with Epichloë festucae var. lolii with different detection methods - A re-evaluation of intoxication risk in Germany?
J Fungi 6:177. doi: 10.3390/jof6030177.

Thurow, C, Krischke, M, Mueller, MJ, Gatz, C (2020) Induction of jasmonoyl-isoleucine (JA-Ile)-dependent JASMONATE ZIM-DOMAIN (JAZ) genes in NaCl-treated Arabidopsis thaliana roots can occur at very low JA-Ile levels and in the absence of the JA/JA-Ile transporter JAT1/AtABCG16.
Plants 9: 1635

Ferber E, Gerhards J, Sauer, M, Krischke, M, Dittrich MT, Müller T, Berger S, Fekete A, Mueller MJ (2020) Chemical priming by isothiocyanates protects against intoxication by products of the mustard oil bomb.
Front. Plant Sci. Jun 26; 11:887. eCollection2020

Shady NH, Khattab AR, Ahmed S, Liu M, Quinn RJ, Fouad MA, Kamel MS, Muhsinah AB, Krischke M, Mueller MJ, Abdelmohsen UR (2020) Hepatitis C virus NS3 protease and helicase inhibitors from red sea sponge (Amphimedon) species in green synthesized silver nanoparticles assisted by in silico modeling and metabolic profiling.
Int. J. Nanomed. 15: 3377-3389.

Zahran EM, Abdelmohsen UR, Shalash MM, Salem MA, Khalil HE, Desoukey SY, Fouad MA, Krischke M, Mueller M, Kamel MS. (2020) Local anaesthetic potential, metabolic profiling, molecular docking and in silico ADME studies of Ocimum forskolei, family Lamiaceae.
Nat Prod Res. Jan 30:1-7. doi: 10.1080/14786419.2020.1719489.

Krauss J, Vikuk V, Young CA, Krischke M, Mueller MJ, Baerenfaller K. (2020) Epichloë endophyte infection rates and alkaloid content in commercially available grass seed mixtures in Europe.
Microorganisms. 8(4). pii: E498. doi: 10.3390/microorganisms8040498.

Correction: Krauss, J., et al. Epichloë Endophyte Infection Rates and Alkaloid Content in Commercially Available Grass Seed Mixtures in Europe. Microorganisms 2020, 8, 498.

Osman M, Stigloher C, Mueller MJ, Waller F. (2020) An improved growth medium for enhanced inoculum production of the plant growth-promoting fungus Serendipita indica.
Plant Methods 16:39. doi: 10.1186/s13007-020-00584-7.

Gomaa AA, Samy MN, Abdelmohsen UR, Krischke M, Mueller MJ, Wanas AS, Desoukey SY, Kamel MS. (2020) Metabolomic profiling and anti-infective potential of Zinnia elegans and Gazania rigens (Family Asteraceae).
Nat Prod Res. 2020, Sep;34(18):2612-2615.


Schäbler S, Amatobi KM, Horn M, Rieger D, Helfrich-Förster C, Mueller MJ, Wegener C, Fekete A (2020) Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation.
Cell Mol Life Sci. 2020 Jan 20. doi: 10.1007/s00018-019-03441-6.

Youssif KA, Haggag EG, Elshamy AM, Rabeh MA, Gabr NM, Seleem A, Salem MA, Hussein AS, Krischke M, Mueller MJ, Abdelmohsen UR (2019) Anti-Alzheimer potential, metabolomic profiling and molecular docking of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea aqueous extracts.
PLoS One, 14(11): e0223781. doi: 10.1371/journal.pone.0223781.

Elmaidomy AH, Mohammed R, M Hassan H, I Owis A, E Rateb M, A Khanfar M, Krischke M, Mueller MJ, Ramadan Abdelmohsen U. (2019) Metabolomic profiling and cytotoxic tetrahydrofurofuran lignans investigations from Premna odorata Blanco.
Metabolites. 9(10). pii: E223. doi: 10.3390/metabo9100223.

Vikuk V, Young CA, Lee ST, Nagabhyru P, Krischke M, Mueller MJ, Krauss J. (2019) Infection Rates and Alkaloid Patterns of Different Grass Species with Systemic Epichloë Endophytes.
Appl Environ Microbiol. 85(17): e00465-19. doi: 10.1128/AEM.00465-19.

Glenz R, Schmalhaus D, Krischke M, Mueller MJ, Waller F. (2019) Elevated levels of phosphorylated sphingobases Do not antagonize sphingobase- or fumonisin B1-induced plant cell death.
Plant Cell Physiol. 60:1109-1119.


Abdelhafez OH, Fawzy MA, Fahim JR, Desoukey SY, Krischke M, Mueller MJ, Abdelmohsen UR. (2018) Hepatoprotective potential of Malvaviscus arboreus against carbon tetrachloride-induced liver injury in rats.
PLoS One 13(8):e0202362.

Findling S, Stotz HU, Zoeller M, Krischke M, Zander M, Gatz C, Berger S, Mueller MJ (2018) TGA2 signaling in response to reactive electrophile species is not dependent on cysteine modification of TGA2.
PLoS One 13(4):e0195398.


Mueller SP, Unger M, Guender L, Fekete A, Mueller MJ (2017) Phospholipid:Diacylglycerol Acyltransferase-Mediated Triacylglycerol Synthesis Augments Basal Thermotolerance.
Plant Physiol. 175, 486 - 497.

Cheng C, Balasubramanian S, Fekete A, Krischke M, Mueller MJ, Hentschel U, Oelschlaeger TA, Abdelmohsen UR (2017) Inhibitory potential of strepthonium A against Shiga toxin production in enterohemorrhagic Escherichia coli (EHEC) strain EDL933.
Nat. Prod. Res. 31, 2818-2923.

Oenel, A, Fekete, A, Krischke, M, Faul, SC, Gresser, G, Havaux, M, Mueller, MJ, Berger, S (2017) Enzymatic and non-enzymatic mechanisms contribute to lipid oxidation during seed aging.
Plant Cell Physiol. 58, 925-933.

Fuchs B, Breuer T, Findling S, Krischke M, Mueller MJ, Holzschuh A, Krauss J. (2017) Enhanced aphid abundance in spring desynchronizes predator-prey and plant-microorganism interactions.
Oecologia 183, 469-478.


Blättner S, Das S, Paprotka K, Eilers U, Krischke M, Kretschmer D, Remmele CW, Dittrich M, Müller T, Schuelein-Voelk C, Hertlein T, Mueller MJ, Huettel B, Reinhardt R, Ohlsen K, Rudel T, Fraunholz MJ. (2016) Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes.
PLoS Pathog. 12:e1005857.

Segerer G, Hadamek K, Zundler M, Fekete A, Seifried A, Mueller MJ, Koentgen F, Gessler M, Jeanclos E, Gohla A. (2016) An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.
Sci Rep. 6, 35160.

Muench M, Hsin CH, Ferber E, Berger S, Mueller MJ. (2016) Reactive electrophilic oxylipins trigger a heat stress-like response through HSFA1 transcription factors.
J. Exp. Bot. 67, 6139-6148.

Cerveau, D., Kraut, A., Stotz, H.U., Mueller, M.J., Coute, Y., Rey, P. (2016) Characterization of the Arabidopsis thaliana 2-Cys peroxiredoxin interactome.
Plant Sci. 252, 30-41.

Walper E, Weiste C, Mueller MJ, Hamberg M, Dröge-Laser W. (2016) Screen Identifying Arabidopsis Transcription Factors Involved in the Response to 9-Lipoxygenase-Derived Oxylipins.
PLoS One 11(4):e0153216.

Ruemer S, Krischke M, Fekete A, Lesch M, Mueller MJ, Kaiser WM. (2016) Methods to Detect Nitric Oxide in Plants: Are DAFs Really Measuring NO?
Methods Mol Biol. 1424, 57-68.


Hartmann L, Pedrotti L, Weiste C, Fekete A, Schierstaedt J, Göttler J, Kempa S, Krischke M, Dietrich K, Mueller MJ, Vicente-Carbajosa J, Hanson J, Dröge-Laser W. (2015) Crosstalk between two bZIP signaling pathways orchestrates salt-induced metabolic reprogramming in Arabidopsis roots.
Plant Cell 27, 2244-2260.

Mueller SP, Krause DM, Mueller MJ, Fekete A. (2015) Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation.
J. Exp. Bot. 66, 4517-4526.

Mülek M, Fekete A, Wiest J, Holzgrabe U, Mueller MJ, Högger P. (2015) Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach.
J. Pharm. Biomed. Anal. 114, 71-81.

Awad, J., Stotz, H.U., Fekete, A., Krischke, M., Engert, C., Havaux, M., Berger, S., Mueller, M.J.  (2015) 2-Cys peroxiredoxins and thylakoid peroxidase create a water-water cycle that is essential to protect the photosynthetic apparatus under high light stress conditions.
Plant Physiol. 167, 1592-1603.

Ahmed, Z., Mayr, M., Zeeshan, S., Dandekar, T., Mueller, M.J., Fekete, A. (2015) Lipid-Pro: a computational lipid identification solution for untargeted lipidomics on data-independent acquisition tandem mass spectrometry platforms.
Bioinformatics 31(7), 1150-1153.


Stotz, H.U., Findling, S., Nukarinen, E., Weckwerth, W., Mueller, M.J., Berger, S. (2014) A tandem affinity purification tag of TGA2 for isolation of interacting proteins in Arabidopsis thaliana.
Plant Signal. Behavior 9(10):e972794.

Scholl C, Wang Y, Krischke M, Mueller MJ, Amdam GV, Rössler W. (2014) Light exposure leads to reorganization of microglomeruli in the mushroom bodies and influences juvenile hormone levels in the honeybee.
Dev Neurobiol. 74, 1141-1153.

Alsharafa, K., Vogel, M.O., Oelze, M.L., Moore, M., Stingl, N., König, K., Friedman, H., Mueller, M.J., Dietz, K.J. (2014) Kinetics of retrograde signalling initiation in the high light response of Arabidopsis thaliana.
Philos Trans R Soc Lond B Biol Sci. 369(1640), 20130424. doi: 10.1098/rstb.2013.0424.

Klinkenberg, J., Faist, H., Saupe, S., Lambertz, S., Krischke, M., Stingl, N., Fekete, A., Mueller, M.J., Feussner, I., Hedrich, R., Deeken, R. (2014) Two Fatty Acid Desaturases, STEAROYL-ACYL CARRIER PROTEIN Δ9-DESATURASE6 and FATTY ACID DESATURASE3, Are Involved in Drought and Hypoxia Stress Signaling in Arabidopsis Crown Galls.
Plant Physiol. 164, 570-583.


Fuchs, B., Krischke, M., Mueller, M.J., Krauss, J. (2013) Peramine and olotrem B from endophyte-grass associations cascade up the food chain.
J. Chem. Ecol. 39, 1385-1389.

Schiebel, J., Kapilashrami, K., Fekete, A., Bommineni, G.R., Schaefer, C.M., Mueller, M.J., Tonge, P.J., Kisker, C. (2013) Structural basis for the recognition of mycolic acid precursors by KasA, a condensing enzyme and drug target from Mycobacterium tuberculosis.
J. Biol. Chem. 288, 34190-34204.

Boca, S., Koestler, F., Ksas, B., Chevalier, A., Leymarie, J., Fekete, A., Mueller, M.J., Havaux, M. (2013) Arabidopsis lipocalins AtCHL and AtTIL have distinct but overlapping functions for lipid protection and seed longevity.
Plant Cell Environ. 37, 368-381.

Pedrotti, L., Mueller, M.J., Waller, F. (2013) Piriformospora indica root colonization triggers local and systemic root responses and inhibits secondary colonization of distal roots.
PLloS One (8(7):e69352.doi: 10.1371/journal.pone.0069352.

Ramel, F., Ksas, B., Akkari, E., Mialoundama, A.S., Monnet, F., Krieger-Liszkay, A., Ravanat, J-L., Mueller, M.J., Bouvier, F., Havaux, M. (2013) ight-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen.
Plant Cell 25, 1445-1462.

Farmer, E.E., Mueller, M.J. (2013) ROS-mediated lipid peroxidation and RES-activated signalling.
Ann. Rev. Plant Biology 64, 22.1-22.22.

Grebner, W., Stingl, N.E., Oenel, A., Mueller, M.J., Berger, S. (2013) Lipoxygenase 6 - dependent oxylipin synthesis in roots is required for abiotic and biotic stress resistance of Arabidopsis thaliana.
Plant Physiol. 161, 2159-2170.

Stotz, H.U., Mueller, S., Zoeller, M., Mueller, M.J., Berger, S. (2013) TGA transcription factors and jasmonate-independent COI1 signalling regulate specific plant responses to reactive oxylipins.
J. Exp. Bot. 64, 963-974.

Leikam, C., Hufnagel, A., Walz, S., Kneitz, S., Fekete, A., Müller, M.J., Eilers, M., Schartl, M., Meierjohann, S. (2013) Cystathionase mediates senescence evasion in melanocytes and melanoma cells.
Oncogene 33, 771-782.

Stingl, N., Krischke, M., Fekete, A., Mueller, M.J. (2013) Analysis of defense signals in Arabidopsis thaliana leaves by ultra performance liquid chromatography/ tandem mass spectrometry: jasmonates, salicylic acid, abscisic acid.
Methods Mol. Biol. 1009, 103-113.


Zoeller, M., Stingl, N., Krischke, M., Fekete, A., Waller, F., Berger, S., Mueller, M.J. (2012) Mechanisms and targets of lipid oxidation in the incompatible Pseudomonas-Arabidopsis interaction: Biogenesis of azelaic and pimelic acid.
Plant Physiol. 160, 365-78.

Rümer S, Krischke M, Fekete A, Mueller MJ, Kaiser WM. (2012) DAF-fluorescence without NO: Elicitor treated tobacco cells produce fluorescing DAF-derivatives not related to DAF-2 triazol.
Nitric Oxide 27, 123-135.

Kupke, J., Spaethe, J., Mueller, M.J., Rössler, W., Albert S. (2012) Molecular and biochemical characterization of the major royal jelly protein in bumblebees suggest a non-nutritive function.
Insect. Biochem. Mol. Biol. 42, 647-654.

Ott, C., Ross, K., Straub, S., Thiede, B., Götz, M., Goosmann, C., Krischke, M., Mueller, M.J., Krohne, G., Rudel, T., Kozjak-Pavlovic, V. (2012) Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes.
Mol. Cell. Biol. 32, 1173-1188.


Albert, S., Gätschenberger, H., Azzami, K., Gimple, O., Grimmer, O., Sumner, S., Fujiyuki, T., Tautz, J., Mueller, M.J. (2011) Evidence of a novel immune response protein in the Hymenoptera.
Insect Biochem. Mol. Biol. 41, 968-981.

Stotz, H.U., Jikumaru, Y., Shimada, Y., Y., Sasaki, E., Stingl, N., Mueller, M.J., Kamiya, Y. (2011) Jasmonate-dependent and COI1-independent defense responses against sclerotinia sclerotium in Arabidopsis thaliana: Auxin is part of COI1-independent defense signalling.
Plant Cell Physiol. 52, 1941-1956.

Peer, M., Bach, M., Mueller, M.J., Waller, F. (2011 Free sphingobases induce RBDOHD-dependent reactive oxygen species production in Arabidopsis thaliana leaves.
FEBS Lett. 585, 3006-3010.

Birtic, S., Ksas, B., Genty, B., Mueller, M.J., Triantaphylidès, C., Havaux, M. (2011) Using spontaneous photon emission to image lipid oxidation patterns in plant tissues.
Plant J. 67, 1103-1115.

Sogabe, Y., Nakamura, H., Nagakawa, T., Hasegawa, S., Asano, T., Ohta, H., Yamaguchi, K., Mueller, M.J., Kodama, H., Nishiuchi, T. (2011) Visualization of Wounding-induced Root-to-Shoot Communication in Arabidopsis.
Plant Signal Behav., 6, 1057-1039.

Hasegawa, S., Sogabe, Y., Asanao, T., Nakagawa, T., Nakamura, H., Kodama, H., Ohta, H., Yamaguchi, K., Mueller, M.J., Nishiuchi, T. (2011) Gene expression analysis of wounding-induced root-to-shoot communication in Arabidopsis thaliana.
Plant Cell Environ., 34, 705-716.




Peer, M., Stegmann, M., Mueller, M.J., Waller, F. (2010) Pseudomonas syringae infection triggers de novo synthesis of phytosphingosine from sphinganine in Arabidopsis thaliana.
FEBS Lett., 584, 4053-4056.

Ellinger, S., Stingl, N.E., Kubigsteltig, I.I., Bals, T., Juenger, M., Pollmann, S., Berger, S., Schünemann, D., Mueller, M.J. (2010) DGL and DAD1 lipases are not essential for wound- and pathogen-induced jasmonate biosynthesis: redundant lipases contribute to jasmonate formation.
Plant Physiol. 153, 114-127.

Seltmann, M.A., Stingl, N.E., Lautenschlaeger, J.,K., Krischke, M., Mueller, M.J., Berger, S. (2010) Differential impact of lipoxygenase 2 and jasmonates on natural and stress-induced senescence in  Arabidopsis thaliana.
Plant Physiol., 152, 1940-1950.

Bruinsma, M., van Broekhoven, S., Poelman, E.H., Posthumus, M.A., Mueller, M.J., van Loon, J.J., Dicke, M. (2010) Inhibition of lipoxygenase affects induction of both direct and indirect plant defences against herbivorous insects.
Oecologia 162, 293-404.

Gilles, S., Jacoby, D., Blume, C., Mueller, M.J., Jakob, T., Behrendt, H., Schaekel, K., Traidl-Hoffmann, C. (2010) Pollen-derived low-molecular weight factors inhibit 6-sulfo LacNAc1 dendritic cells' capacity to induce T-helper type 1 responses.
Clin. Exp. All. 40, 269-278.

Mueller, M.J. (2010) Isoprostane nomenclature: inherent problems may cause setbacks for the development of the isoprostanoid field.
Prostaglandins Leukot. Essent. Fatty Acids 82, 71-81.


Gilles, S., Mariani, V., Bryce., M., Mueller, M.J., Ring, J., Behrendt, H., Jakob, T., Traidl-Hoffmann, C. (2009) Pollen allergens do not come alone: pollen associated lipid mediators (PALMS) shift the human immue systems towards a Th2-dominated response.
Allergy, Asthma & Clin. Immun. 5, 3.

Durand, T., Bultel-Poncé, V., Guy, A., Berger, S., Mueller, M.J., Galano, J.-M. (2009) New Bioactive Oxylipins Formed by Non-enzymatic Free-Radical-Catalyzed Pathways: The Phytoprostanes.
Lipids 44, 875-878.

Mueller, M.J. (2009) Reactive electrophilic oxylipins: Pattern recognition and signaling.
Phytochemistry 70, 1511-1521.

Barden, A.E., Croft, K.D., Durand, T., Guy, A., Mueller, M.J., Mori, T.A. (2009) Flaxseed oil supplementation increases F1-phytoprostanes in healthy men.
J. Nutrition 139, 1890-1895.

Gilles, S., Mariani, V., Bryce, M., Mueller, M.J., Ring, J., Jakob, T., Pastore, S., Behrendt, H., Traidl-Hoffmann, C. (2009) Pollen derived E1-phytoprostanes signal via PPARg and NF-kB dependent mechanisms.
J. Immunol. 182, 6653-6658.

Bruinsma, M., Posthumus, M.A., Mumm, R., Mueller, M.J., van Loon, J.J.A., Dicke, M. (2009) Jasmonic acid-induced volatiles of Brassica oleracea attract parasitoid: effects of time, dose and comparison with induction by herbivores.
J. Exp. Bot. 60, 2575-2587.
Comment: Wasternack, C., Hause, B. (2009) Emerging complexity: jasmonate induced volatiles affect paraitoid choice.
J. Exp. Bot. 60, 2451-2453.

Yarali, A., Krischke, M., Michels, B., Saumweber, T., Mueller, M.J., Gerber, B. (2009)
Genetic distortion of the balance between punishment and relief learning in Drosophila.,
J. Neurogenet. 23, 235-247.


Dueckershoff, K., Mueller, S., Mueller, M.J., Reinders, J. (2008) Impact of cyclopentenone-oxylipins on the proteome of Arabidopsis thaliana.
Biochim. Biophys. Acta (Proteins and Proteomics) 1784, 1975-1985.

Triantaphylides, C., Krischke, M., Hoeberichts, F.A., Ksas, B., Gresser, G., Havaux, M., Van Breusegem, F., Mueller, M.J. (2008) Singlet oxygen is the major reactive oxygen species involved in photo-oxidative damage to plants.
Plant Physiol. 148, 960-968.

Randolt K., Gimple, O., Geißendörfer, J., Reinders, J., Prusko, C., Mueller, M.J., Albert, S., Tautz, J., Beier, H. (2008) Immune-related proteins induced in the hemolymph after aseptic and septic injury differs in honey bee worker larvae and adults.
Arch. Insect Biochem. Physiol. 69, 155-167.

Mueller, S., Hilbert, B., Dueckershoff, K., Roitsch, T., Krischke, M., Mueller, M.J., Berger, S. (2008) General detoxification and stress responses are mediated by oxidized lipids through TGA transcription factors in Arabidopsis.
Plant Cell 20, 768-785.
Comment: Eckhardt, N.A. (2008) Oxylipin signaling in plant stress responses.
Plant Cell 20, 495-497.


Feldhaar, H., Straka, J., Krischke, M., Berthold, K., Stoll, S., Mueller, M.J., Gross, R. (2007) Nutritional upgrading for omnivor carpenter ants by the endosymbiont Blochmania.
BMC Biology 5, 48.

Efetova, M., Zeier, J., Riederer, M., Lee, C.W., Stingl, N., Mueller, M.J., Hartung, W, Hedrich, R., Deeken, R.  (2007) A central role of ABA in drought stress protection of Agrobacterium-induced  tumors on Arabidopsis,
Plant Physiol. 145, 853-862.

Schoenleben, S., Sickmann, A., Mueller, M.J., Reinders, J. (2007) Proteome analysis of Apis mellifera royal jelly.
Anal. Bioanal. Chem. 389, 1087-1093.

Arts, M.J., Grun, C., de Jong, R.L., Voss, H.-P., Bast, A., Mueller, M.J., Haenen, G.R. (2007) Oxidative degradation of lipids during mashing.
J. Agric. Food Chem. 22, 7010-7014.

Mariani, V., Gilles, S., Jakob, T., Thiel, M., Mueller, M.J., Ring, J., Behrendt, H., Traidl-Hoffmann, C. (2007) Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and licence them for Th2 attraction.
J. Immunol. 178, 7623-7631.

Gutermuth, J., Bewersdorff, M., Traidl-Hoffmann, C., Ring J., Mueller, M.J., Behrendt, H., Jakob, T. (2007) Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivo.
J. Allergy Clin. Immunol. 120, 293-299.

Grun, C., Berger, S., Matthes, D., Mueller, M.J. (2007) Early accumulation of non-enzymatically synthesized oxylipins in Arabidopsis thaliana after infection with Pseudomonas syringae.
Funct. Plant Biology 34, 1-7.

Berger, S., Benediktyova,  Z., Matous, K., Bonfig,  K., Mueller,  M.J., Nedbal,  L., Roitsch, T. (2007) Visualization of dynamics of plant-pathogen interaction by novel combination of chlorophyll fluorescence imaging and statistical analysis: differential effects of virulent and avirulent strains of P. syringae and of oxylipins on A. thaliana.
J. Exp. Bot. 58, 797-806.

Karg, K., Dirsch, V., Vollmar, A.M., Cracowski, J.-L., Laporte, F., Mueller, M.J. (2007) Biologically active oxidized lipids (phytoprostanes) in the plant diet and parenteral nutrition.
Free Rad. Res. 41, 25-37.


Sattler, S.E., Mene-Saffrane, L., Farmer, E.E., Krischke, M., Mueller, M.J., DellaPenna, D. (2006) Non-enzymatic lipid peroxidation reprograms gene expression and activates defense markers in tocopherol deficient mutants.
Plant Cell 18, 3706-3720.

Deeken, R., Engelmann, J.C., Efetova, M., Czirjak, T., Müller, T., Kaiser, W.M., Tietz, O., Krischke, M., Mueller, M.J., Palme, K., Dandekar, T., Hedrich, R. (2006) An Integrated View of Gene Expression and Solute Profiles of Arabidopsis Tumors: A Genome-Wide Approach.
Plant Cell 18, 3617-3634.

Raake, I., Mueller, M.J., Berger, S. (2006) Defects in allene oxide synthase and OPDA reductase alter the resistance to Pseudomonas syringae and Botrytis cinerea.
J. Phytopath. 154, 740-744.

Raake, I., v. Rad, U., Mueller, M.J., Berger, S. (2006) Yeast increases resistance in Arabidopsis against Pseudomonas syringae and Botrytis cinerea by plant-dependent as well as plant independent mechanism.
Mol. Plant Microbe Interaction 19, 1138-1146.

Mueller, M.J., Laurent, M.-S., Grun, C., Karg, K., Farmer, E.E. (2006) Oxylipin analysis.
Plant J. 45, 472-489.


De Vos, M., Van Oosten, V.R., Van Poecke, R.M.P., Van Pelt, J.A., Pozo, M.J., Mueller, M.J., Buchala, A.J., Métraux, J.-P., Van Loon, L.C., Dicke, M., Pieterse, C.M.J.  (2005) Signal signature and transcriptome changes of Arabidopsis during pathogen and insect attack.
Mol. Plant-Microbe Interact. 18, 923-937.

Traidl-Hoffmann, C., Mariani, V., Hochrein, H., Karg, K., Wagner, H., Ring, J., Mueller, M.J., Jakob, T., Behrendt, H. (2005) Pollen associated phytoprostanes inhibit dendritic cell IL-12 production and augment Th2 cell polarization.
J. Exp. Med. 201, 627-636. (Highlight article).
Comments: Pollen polarize dentritic cells (2005) J.Exp.Med. 201: 486; Pollen power (2005) Nat. Med. 11: 259; Allergic oil (2005), Nat. Immun. 6, 371.

Loeffler, C., Berger, S., Durand, T., Bringmann, G., Dreyer, M., von Rad, U., Durner, J., Mueller, M.J. (2005) B1-phytoprostanes trigger plant defence and detoxification responses.
Plant Physiol. 137, 328-340.

Iqbal, M., Evans, P., Lledó, A., Verdaguer, X., Pericás, M.A., Riera, A., Loeffler, C., Sinha, A.K., Mueller, M.J. (2005) Total synthesis and biological activity of 13,14-dehydro-12-oxo-phytodienoic acids (deoxy-J1-phytoprostanes).
Chem. Bio. Chem. 6, 276-280.

von Rad, U., Mueller, M.J., Durner, J. (2005) Evaluation of natural and synthetic stimulants of plant immunity by microarray technology.
New Phytologist 165, 191-202.


Mueller, M.J. (2004) Phytoprostanes: bioactive isoprostanes from plants.
Prostaglandins, Leukot. Essential Fatty Acids 71, 39-40.

Stuhlfelder, C., Mueller, M.J., Warzecha, H., (2004) Cloning and expression of a tomato cDNA encoding a methyl jasmonate cleeaving esterase.
Eur. J. Biochem. 271, 2976-2983.

Mueller, M.J. (2004) Archetype signals in plants: the phytoprostanes.
Curr. Opin. Plant Biol. 7, 441-448.

Zeier, J., Pink, B., Mueller, M.J., Berger, S., (2004) Light conditions influence specific defense responses in incompatible plant-pathogen interactions: uncoupling systemic resistance from salicylic acid and PR-1 accumulation.
Planta 219, 673-683.

Huang, X., Stettmaier, K., Michel, C., Hutzler, P., Mueller, M.J., Durner, J. (2004) Nitriooxide is induced by wounding and influences jasmonic acid signaling in Arabidopsis thaliana.
Planta 218, 938-946.

Thoma, I., Krischke, M., Loeffler, C., Mueller, M.J. (2004) The isoprostanoid pathway in plants.
Chem. Phys. Lipids 128, 135-148.


Loeffler, C., Thoma, I., Krischke, M., Mueller, M.J. (2003) The dinor isoproatane pathway in plants.
Adv. Exp. Med. Biol. 525, 217-220.

Thoma, I., Loeffler, C., Sinha, A., Gupta, M., Krischke, M., Steffan, B., Roitsch, T., Mueller, M.J.  (2003) Cyclopentenone isoprostanes induced by reactive oxygen species trigger defense gene activation and phytoalexin accumulation in plants (Highlight article),
Plant J. 34, 363-375.

Krischke, M., Loeffler, C., Mueller, M.J., (2003) Archetypische Prostanoide in Pflanzen.
Bioforum 3, 2-4.

Spoel, S.H., Koornneef, A., Claessens, S.M.C., Korzelius, J.P., van Pelt, J.A., Mueller, M.J., Buchala, A.J., Metraux, J.-P., Brown, R., Kazan, K., van Loon, L.C., Dong, X., Pieterse, (2003) NPR1 modulates cross-talk between salicylate- and jasmonate-dependent plant defense pathways through a novel function in the cytosol.
Plant Cell 15, 760-770.

Krischke, M., Loffler, C., Mueller, M.J. (2003) Biosynthesis of 13,14-dehydro-12-oxo-phytodienoic acid and related cyclopentenones via the phytoprostane D1 pathway.
Phytochemistry 62, 351-358.


Stuhlfelder, C., Lottspeich, F., Mueller, M.J. (2002) Purification and partial amino acid sequences of an esterase from tomato.
Phytochemistry 60, 233-240.

Mueller, M.J. (2002) Prostaglandin-like octadecanoids in plants: Biosynthesis, molecular signalling and response to environment.
Lipid biotechnology, Marcel Dekker, New York, (eds. Kuo Gardner), 203-229.


Pieterse, C.M.J., van Pelt, J.A., Ton, J., Parchmann, S., Mueller, M.J., Buchala, A.J., Metraux, J.-P., van Loon, L.C. (2000) Rhizobacteria-mediated induced systemic resistance (IRS) in Arabidopsis requires sensitivity to jasmonate and ethylene but is not accompanied by an increase in their production.
Physiol. Mol. Plant Pathol. 57, 123-134.

Imbusch, R., Mueller, M.J. (2000) Analysis of oxidative stress and wound-inducible dinor isoprostanes F1 (phytoprostanes F1) in plants.
Plant Physiol. 124, 1293-1304.

Imbusch, R., Mueller, M.J. (2000) Dinor isoprostanes F1 formation in higher plants: High concentrations in plant drugs and flower pollen.
Free Rad. Biol. Med. 28, 720-726.


O'Sullivan, S., Mueller, M.J., Dahlén, S.-E., Kumlin, M. (1999) Analyses of prostaglandin D2 metabolites in urine: comparison between enzyme immunoassay and negative ion chemical ionisation gas chromatography - mass spectrometry.
Prostaglandins Other Lipid Med. 57, 149-165.

Menke, F.L.H., Parchmann, S., Mueller, M.J., Kijne, J.W., Memelink, J. (1999) Involvement of the octadecanoid pathway and protein phosphorylation in fungal-elicitor-induced expression of terpenoid indole alkaloid biosynthetic genes in Catharanthus roseus.
Plant Physiol. 199, 1289-1296.


Mueller, M.J. (1998) Redically novel prostaglandins in animals and plants: The isoprostanes.
Chemistry & Biology 5, 323-333.

Parchmann, S., Mueller, M.J. (1998) Evidence for the formation of dinor isoprostanes E1 from a-linolenic acid in plants.
J. Biol. Chem., 273, 32650-32655.

Krischer, S.M., Eisenmann, M., Mueller, M.J. (1998) Transport of arachidonic acid across the neutrophil plasma membrane via a protein-facilitated mechanism.
Biochemistry, 37, 12884-12891.

Mueller, M.J., Blomster Andberg, M., Haeggström, J.Z. (1998) Analysis of the molecular mechanism of substrate-mediated inactivation of leukotriene A4 hydrolase.
J. Biol. Chem. 273, 11570-11575.


Parchmann, S., Gundlach, H., Mueller, M.J. (1997) Inducation of 12-oxo-phytodienoic acid in wounded plants and elicited plant cell cultures.
Plant Physiol. 115, 1057-1064.

Mueller, M.J. (1997) Enzymes involved in jasmonic acid biosynthesis.
Physiol. Plant. 100, 653-663.

Krischer, S.M., Eisenmann, M., Bock, A., Mueller, M.J. (1997) Protein-facilitated export of arachidonic acid from pig neutrophils.
J. Biol. Chem. 272, 10601-10607.


Wetterholm, A., Mueller, M.J., Blomster, M., Samuelsson, B., Haeggström, J.Z. (1996) Studies on the active site of leukotriene A4 hydrolase.
Adv. Exp. Med. Biol. 407, 1-7.

Mueller, M.J., Blomster Andberg, M., Samuelson, B., Haeggström, J.Z. (1996) Leukotriene A4 hydrolase, mutation of tyrosine 378 allows conversion of leukotriene A4 into an isomer of leukotriene B4.
J. Biol. Chem. 271, 24345-24348.

Mueller, M.J., Blomster, M., Oppermann, Jörnvall, H., Samuelsson, B., Haeggström, J.Z. (1996) Leukotriene A4 hydrolase: Dissociation of catalysis and mechanism-based inactivation by mutation of tyrosine-378.
Proc. Natl. Acad. Sci. USA 93, 5931-5935.


Mueller, M.J., Wetterholm, A., Blomster, M., Jörnvall, H., Samuelsson, B., Haeggström, J.Z. (1995) Leukotriene A4 hydrolase: Mapping of a heneicosapeptide involved in mechanism-based inactivation.
Proc. Natl. Acad. Sci. USA 92, 8383-8387.

Mueller, M.J., Wetterholm, A., Blomster, M., Jörnvall, H., Samuelsson, B., Haeggström, J.Z. (1995) Leukotriene A4 hydrolase: Evidence for a catalytic role of tyrosine-383 in the peptidase reaction.
Eur. J. Biochem. 231, 528-534.

Mueller, M.J. (1995) Der Leukotriensignalweg - ein vielversprechender Ansatzpunkt für Inhibitoren in der Therapie entzündlicher Erkrankungen.
Pharmazie in unserer Zeit 24 (5), 264-272.

Mueller, M.J., Samuelsson, B., Haeggström, J.Z. (1995) Chemical Modification of Leukotriene A4 hydrolase: Essential Arginyl and Tyrosyl Residues at the active site.
Biochemistry 34, 3536-3543.

Blechert, S., Brodschelm, W., Hölder, S., Kammerer, L., Kutchan, T.M., Mueller, M.J., Xia, Z. -Q., Zenk, M.H. (1995) The octadecanoic pathway: Signal molecules for the regulation of secondary pathways.
Proc. Natl. Acad. Sci. USA 92, 4099-4105.


Mueller, M.J., Brodschelm, W. (1994) Quantification of Jasmonic Acid by Capillary Gas Chromatography-Negative Chemical Ionization-Mass Spectrometry.
Anal. Biochem. 218, 425-435.


Mueller, M.J., Brodschelm, W., Spannagl, E., Zenk, M.H. (1993) Signaling in the elicitation process is mediated through the octadecanoid pathway leading to jasmonic acid.
Proc. Natl. Acad. Sci. USA 90, 7490-7494.

Mueller, M.J., Zenk, M. H. (1993) The Biosynthesis of the Cularine Alkaloids.
Liebigs Ann. Chem. 557-563.

Mueller, M.J., Zenk, M.H. (1993) Early Precursors in the Biosynthesis of Cularine-Type Benzylisoquinoline Alkaloids.
J. Chem. Soc., Chem. Comm. 1, 73-75.


Mueller, M.J., Zenk, M.H. (1992) The Norcoclaurine Pathway is operative in Berberine Biosynthesis in Coptis japonica.
Planta Med. 58, 485-574.

Gundlach, H., Müller, M.J., Kutchan, T.M., Zenk, M.H. (1992) Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures.
Proc. Natl. Acad. Sci. USA 89, 2389-2393.

Mueller, M.J. (1992) Die Biosynthese der Benzylisochinolinalkaloide vom Cularin-Typ sowie Untersuchungen zum Elicitierungsgeschehen in pflanzlichen Zellkulturen. Dissertation, Ludwigs-Maximilian-Universität München.