piwik-script

English Intern
    Sonderforschungsbereich 1047

    Projekt A1 Förster

    Das circadiane Uhrnetzwerk ausgewählter Insekten

    Zusammenfassung

    Eine wichtige Voraussetzung zum Verständnis des täglichen “Timing” von Insekten ist die funktionelle Charakterisierung des neuronalen Uhrennetzwerks im Gehirn. Wir werden zu diesem Verständnis beitragen, indem wir das Uhrennetzwerk von verschiedenen Drosophila-Arten mit sequenzierten Genomen und mit unterschiedlichen Lebensräumen (z.B. Vorkommen an verschiedenen Breitengraden und auf verschiedenen Meereshöhen) aufklären. Zusätzlich werden wir beginnen die Innere Uhr von selektierten Hymenopterenarten und von verschiedenen Blattlaus-Morphen auf molekularer und neuronaler Ebene zu erforschen. Dabei handelt es sich um Arten, die in den Bereichen B und C untersucht werden.

    Publikationen

    • Vaze, K. M., and Helfrich-Förster, C. (2021) The Neuropeptide PDF Is Crucial for Delaying the Phase of Drosophila’s Evening Neurons Under Long Zeitgeber Periods, J Biol Rhythms 36, 442–460.
    • Pauls, D., Selcho, M., Räderscheidt, J., Amatobi, K. M., Fekete, A., Krischke, M., Hermann-Luibl, C., Ozbek-Unal, A. G., Ehmann, N., Itskov, P. M., Kittel, R. J., Helfrich-Förster, C., Kühnlein, R. P., Mueller, M. J., and Wegener, C. (2021) Endocrine signals fine-tune daily activity patterns in Drosophila, Curr Biol 31, 4076–4087.e5.
    • Beer, K., Härtel, S., and Helfrich-Förster, C. (2021) The Pigment-Dispersing Factor neuronal network systematically grows in developing honey bees, Journal of Comparative Neurology 530, 1321–1340.
    • Schäbler, S., Amatobi, K. M., Horn, M., Rieger, D., Helfrich-Förster, C., Mueller, M. J., Wegener, C., and Fekete, A. (2020) Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation, Cellular and Molecular Life Sciences 77, 4939–4956.
    • Beer, K., and Helfrich-Förster, C. (2020) Post-embryonic Development of the Circadian Clock Seems to Correlate With Social Life Style in Bees, Frontiers in Cell and Developmental Biology 8, 1325.
    • Menegazzi, P., Beer, K., Grebler, V., Schlichting, M., Schubert, F. K., and Helfrich-Förster, C. (2020) A Functional Clock Within the Main Morning and Evening Neurons of D. melanogaster Is Not Sufficient for Wild-Type Locomotor Activity Under Changing Day Length, Frontiers in Physiology 11, 229.
    • Schubert, F. K., Helfrich-Förster, C., and Rieger, D. (2020) Single-cell resolution long-term luciferase imaging in cultivated Drosophila brains, microPublication Biology.
    • Schlichting, M., Menegazzi, P., Rosbash, M., and Helfrich-Förster, C. (2019) A distinct visual pathway mediates high light intensity adaptation of the circadian clock in Drosophila, Journal of Neuroscience 39, 1621–1630.
    • Senthilan, P. R., Grebler, R., Reinhard, N., Rieger, D., and Helfrich-Förster, C. (2019) Role of Rhodopsins as Circadian Photoreceptors in the Drosophila melanogaster, Biology 8, 6.
    • Horn, M., Mitesser, O., Hovestadt, T., Yoshii, T., Rieger, D., and Helfrich-Förster, C. (2019) The Circadian Clock Improves Fitness in the Fruit Fly, Drosophila melanogaster, Front Physiol 10, 1374.
    • Schlichting, M., Weidner, P., Diaz, M., Menegazzi, P., Dalla-Benetta, E., Helfrich-Foerster, C., and Rosbash, M. (2019) Light-mediated circuit switching in the Drosophila neuronal clock network, Current Biology 29, 3266–3276.e3.
    • Bertolini, E., Schubert, F. K., Zanini, D., Sehadová, H., Helfrich-Förster, C., and Menegazzi, P. (2019) Life at High Latitudes Does Not Require Circadian Behavioral Rhythmicity under Constant Darkness, Current Biology 29, 3928–3936.e3.
    • Nagy, D., Cusumano, P., Andreatta, G., Anduaga, A. M., Hermann-Luibl, C., Reinhard, N., Gesto, J., Wegener, C., Mazzotta, G., Rosato, E., Kyriacou, C. P., Helfrich-Förster, C., and Costa, R. (2019) Peptidergic signaling from clock neurons regulates reproductive dormancy in Drosophila melanogaster, PLoS Genet 15, e1008158.
    • Beer, K., Kolbe, E., Kahana, N. B., Yayon, N., Weiss, R., Menegazzi, P., Bloch, G., and Helfrich-Förster, C. (2018) Pigment-Dispersing Factor-expressing neurons convey circadian information in the honey bee brain, Open Biology 8, 170224.
    • Beauchamp, M., Bertolini, E., Deppisch, P., Steubing, J., Menegazzi, P., and Helfrich-Förster, C. (2018) Closely Related Fruit Fly Species Living at Different Latitudes Diverge in Their Circadian Clock Anatomy and Rhythmic Behavior, J Biol Rhythms 33, 602–613.
    • Helfrich-Förster, C., Bertolini, E., and Menegazzi, P. (2018) Flies as models for circadian clock adaptation to environmental challenges, European Journal of Neuroscience 51, 116–181.
    • Schlichting, M., Rieger, D., Cusumano, P., Grebler, R., Costa, R., Mazzotta, G., and Helfrich-Förster, C. (2018) Cryptochrome interacts with actin and enhances eye-mediated light sensitivity of the circadian clock in Drosophila melanogaster, Frontiers in Molecular Neuroscience 11, 238.
    • Helfrich-Förster, C. (2018) Sleep in Insects, Annual Review of Entomology 63.
    • Kistenpfennig, C., Grebler, R., Ogueta, M., Hermann-Luibl, C., Schlichting, M., Stanewsky, R., Senthilan, P. R., and Helfrich-Förster, C. (2017) A new Rhodopsin influences light-dependent daily activity patterns of fruit flies, Journal of biological rhythms 32, 406–422.
    • Frenkel, L., Muraro, N. I., González, A. N. B., Marcora, M. S., Bernabó, G., Hermann-Luibl, C., Romero, J. I., Helfrich-Förster, C., Castaño, E. M., Marino-Busjle, C., Calvo, D. J., and Ceriani, M. F. (2017) Organization of Circadian Behavior Relies on Glycinergic Transmission, Cell Reports 19, 72–85.
    • Menegazzi, P., Benetta, E. D., Beauchamp, M., Schlichting, M., Steffan-Dewenter, I., and Helfrich-Förster, C. (2017) Adaptation of circadian neuronal network to photoperiod in high-latitude European Drosophilids, CURR BIOL 27, 833–839.
    • Vaze, K. M., and Helfrich-Förster, C. (2016) Drosophila ezoana uses an hour-glass or highly damped circadian clock for measuring night length and inducing diapause, Physiol Entomol 41, 378–389.
    • Schlichting, M., Menegazzi, P., Lelito, K. R., Yao, Z., Buhl, E., Dalla Benetta, E., Bahle, A., Denike, J., Hodge, J. J., Helfrich-Förster, C., and others. (2016) A neural network underlying circadian entrainment and photoperiodic adjustment of sleep and activity in Drosophila, J Neurosci 36, 9084–9096.
    • Yoshii, T., Hermann-Luibl, C., and Helfrich-Förster, C. (2016) Circadian light-input pathways in Drosophila, Commun Integr Biol 9, e1102805.

    Kontakt/Contact

    Prof. Dr. Charlotte Förster
    Lehrstuhl Neurobiologie und Genetik
    Biozentrum der Universität Würzburg
    Am Hubland
    D-97074 Würzburg

    Phone: +49 931 31-84450 (Sekretariat/Office)
    Mail:    sfb1047@uni-wuerzburg.de
    Web:   Homepage von Charlotte Förster