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    Chair of Biochemistry and Molecular Biology

    AG Wolf

    PD Dr. Elmar Wolf

    Lehrstuhl für Biochemie und Molekularbiologie
    Biozentrum
    Am Hubland
    97074 Würzburg
    Raum B 353

    Tel:   0931 31-83259
    Fax:  0931 31-84113
    elmar.wolf@biozentrum.uni-wuerzburg.de

    Emmy Noether group - Cancer Systems Biology

    Lab News

    November 2019

    We are looking forward to our 1st AG Wolf Retreat from 28th to 30th November 2019!


    October 2019
    And yet another reward for our multitalented Apoorva - Best speaker award at the Eureka_GSLS_2019. Congratulations!!! 

    We are pleased that Yiliam Cruz García joined our team as a senior scientist. Welcome Yiliam!

    September 2019
    Our interns joined as Master students - welcome Beril and Mahmoud!

    We are looking for a HiWi with Felasa-B certificate to support our team. Just drop us an email to Applications.2019.Wolf@gmail.com

    Archive

    Publications

    2019:

    Schmidt S, Gay D, Uthe FW … Wolf E, Strathdee D, Schulze A, Germer CT, Rosenwald A, Sansom OJ, Eilers M, Wiegering A: A MYC–GCN2–eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer, Nature Cell Biology, (2019,  doi:10.1038/s41556-019-0408-0

    Baluapuri A*, Hofstetter J*, Dudvarski Stankovic N, Endres T, Bhandare P, Vos SM, Adhikari B, Schwarz JD, Narain A, Vogt M, Wang S-Y, Düster R, Jung LA, Vanselow JT, Wiegering A, Geyer M, Maric HM, Gallant P, Walz S, Schlosser A, Cramer P, Eilers M, Wolf E: MYC recruits SPT5 to RNA polymerase II to promote processive transcription elongation, Molecular Cell, 2019, 74, https://doi.org/10.1016/j.molcel.2019.02.031 *joined first authors

    Herold S*, Kalb J*, Büchel G*,Ade CP, Baluapuri A, Xu J, Koster J, Solvie D, Carstensen A, Klotz C, Rodewald S, Schülein-Völk C,Dobbelstein M, Wolf E, Molenaar J, Versteeg R,Walz S, Eilers M: Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase, Nature, 2019, 567

    Dammert MA, Brägelmann J, Olsen RR, Böhm S, Monhasery N, Whitney CP, Chalishazar MD, Tumbrink HL, Guthrie MR, Klein S, Ireland AS, Ryan J, Schmitt A, Marx A, Ozretic L, Castiglione R, Lorenz C, Jachimowicz RD, Wolf E, Thomas RK, Poirier JT, Büttner R, Sen T, Byers LA, Reinhardt HC, Letai A, Oliver TG, Sos ML: MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer, Nature Communications,2019, 10, doi: 10.1038/s41467-019-11371-x.

    Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, Mosca R, Campos Y, Tillman H, Roussel MF, Andrew Weesner J, Ellen Fremuth L, Qiu X, Han MJ, Grosveld GC, d'Azzo A, MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat. Nature Communications, 2019, 10, doi: 10.1038/s41467-019-11568-0.

    Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, Cindric-Vranesic A, Kneitz S, Wolf E, Ade CP, Rosenwald A, von Eyss B, Gaubatz S: The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes. Cell Reports, 2019, 27


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    Link to all Publications in PubMed