• HEK-293T cells infected with Chlamydia trachomatis expressing chlamydial deubiquitinase Cdu1-FLAG
Lehrstuhl für Mikrobiologie

Dr. Katarzyna Jobin

Kontakt:

Tel.: +49 (0)931-31 89584
Raum: D222
EMail:

    

2025 – Present  Junior Group Leader at Microbiology and Institute of Systems Immunology (associated), University of Würzburg, Germany.
Topic: Immune-Matrix Dynamics in the Urinary Tract
2019 –2025 Post doctoral researcher in Prof. Wolfgang Kastenmüller laboratory, Max Planck Research Group, Institute of Systems Immunology, University of Würzburg, Germany.
Topic: Dynamics of early anti-viral immune response
2021 – 2022 Parental leave
2018 – 2019 Post doctoral researcher in Prof. Christian Kurts laboratory in the Institute of Molecular Medicine and Experimental Immunology, University of Bonn, Germany.
Topic: Influence of high salt diet on immune response in cancer and UTI.
2014 –2018  PhD Studies in Prof. Christian Kurts laboratory in the Institute of Molecular Medicine and Experimental Immunology, University of Bonn, Germany.
Topic: Influence of high salt diet on immune response in pyelonephritis.
2012 – 2014 Graduate Exchange Scholar and Research Assistant in Dr. Gilbert R. Kinsey laboratory in the Division of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, University of Virginia, USA.
Topic: Role of Tregs in acute kidney injury.
2011 –2012 Graduate Exchange Scholar in Dr. Mark D. Okusa laboratory in the Division of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, University of Virginia, USA.
Topic: Role of Tregs in acute kidney injury.
2010 - 2011 Erasmus Student Exchange in University of Tuscia, Viterbo, Italy.
Topic: Answer of Pleurotus ostreatus to heavy metals and polychlorobiphenyls.
2007 - 2013   Master’s and Bachelor Program in Biology at Jagiellonian University, Krakow, Poland

 

                                     

                       

                                          

Jobin K, Seetharama D, Rüttger L, Fenton C, Kharybina E, Wirsching A, Huang A, Knöpper K, Kaisho T, Busch D, Vaeth M,  Saliba AE, Graw F, Pulfer A, González SF, Zehn D, Liang Y, Ugur M, Gasteiger G, Kastenmüller W., 2025. A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals. Science.

Ugur M, Labios RJ, Fenton C, Knöpper K, Jobin K, Imdahl F, Golda G, Hoh K, Grafen A, Kaisho T, Saliba AE, Grün D, Gasteiger G, Bajénoff M, Kastenmüller W., 2023. Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks. Immunity.

Goldspink A, Schmitz J, Babyak O, Brauns N, Milleck J, Breloh AM, Fleig SV, Jobin K, Schwarz L, Haller H, Wagenlehner F, Bräsen JH, Kurts C, von Vietinghoff S. 2023. Kidney medullary sodium chloride concentrations induce neutrophil and monocyte extracellular DNA traps that defend against pyelonephritis in vivo. Kidney Int.

Jobin K, Müller DN, Jantsch J, Kurts C. 2021. Sodium and its manifold impact on our immune system. Trends Immunol.

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. 2020. A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation. Sci Transl Med.

Breitbach M, Kimura K, Luis TC, Fuegemann CJ, Woll PS, Hesse M, Facchini R, Rieck S, Jobin K, Reinhardt J, Ohneda O, Wenzel D, Geisen C, Kurts C, Kastenmüller W, Hölzel M, Jacobsen SEW, Fleischmann BK, 2018. In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche. Cell Stem Cell Schwab S, Jobin K, Kurts C, 2017. Urinary tract infection: recent insight into the evolutionary arms race between uropathogenic Escherichia coli and our immune system. Nephrol. Dial. Transplant.

Rieck M, Kremser C, Jobin K, Mettke E, Kurts C, Gräler M, Willecke K, Kolanus W, 2017. Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice. Eur. J. Immunol. Jobin K, Heuser C, Kurts C, 2016. A grain of salt on kidney dendritic cell function in allograft rejection. Kidney Int.

Bajwa A, Rosin DL, Chroscicki P, Lee S, Dondeti K, Ye H, Kinsey GR, Stevens BK, Jobin K, Kenwood BM, Hoehn KL, Lynch KR, Okusa MD, 2015. Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury. J. Am. Soc. Nephrol.

Jaworska K, Ratajczak J, Huang L, Whalen K, Yang M, Stevens BK, Kinsey GR, 2015. Both PD-1 ligands protect the kidney from ischemia reperfusion injury. J. Immunol.

Li L, Huang L, Ye H, Song SP, Bajwa A, Lee SJ, Moser EK, Jaworska K, Kinsey GR, Day YJ, Linden J, Lobo PI, Rosin DL, Okusa MD, 2012. Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury. J. Clin. Invest.

Kinsey GR, Huang L, Jaworska K, Khutsishvili K, Becker DA, Ye H, Lobo PI, Okusa MD, 2012. Autocrine adenosine signaling promotes regulatory T cell-mediated renal protection. J. Am. Soc. Nephrol.