Lehrstuhl für Mikrobiologie

    Dr. Cindrilla Chumduri


    Tel.: +49 (0)931-31 86531
    Fax: +49 (0)931-31 84402
    Büro: C243
    EMail:  cindrilla.chumduri@uni-wuerzburg.de


    Kooperation mit fatalem Ergebnis

    Heike Czotscher
    Tel.: 31-89356
    E-mail: czotscher@biozentrum.uni-wuerzburg.de
    Raum: C224

    Naveen Kumar
    Tel.: 31-8
    Raum: C229

    Pon Ganish Prakash
    Tel.: 31- 87648
    Raum: C229

    Academic Career

    1998 – 2003    Studies in Biotechnology at the Bangalore University, India; Master of Science and Bachelor of Science
    2004 – 2005    Junior Research Fellow, Indian Institute of Science, Bangalore, India.
    2005 – 2009    Ph.D at the Max Delbrück Center for Molecular Medicine, Berlin, Dept. Clinical and Molecular Oncology
    2010 – 2012    Postdoctoral fellow at the Max Planck Institute for Infection Biology, Berlin
    2013 – 2016    Research Scientist at the Max Planck Institute for Biology, Berlin
    2017                 Group leader at the Max Planck Institute for Infection Biology, Berlin
    2018                 Group leader at Charité University Medicine, Berlin
    since 2019      Group leader at Chair of Microbiology, University of Würzburg


    Zadora PK, Chumduri C, Imami K, Berger H, Mi Y, Selbach M, Meyer TF, Gurumurthy RK.
    Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to-Mesenchymal Transition in Host Cells.
    Cell Rep. 2019 Jan 29;26(5):1286-1302.e8. doi: 10.1016/j.celrep.2019.01.006.

    Mi Y, Gurumurthy RK, Zadora PK, Meyer TF, Chumduri C.
    Chlamydia trachomatis Inhibits Homologous Recombination Repair of DNA Breaks by Interfering with PP2A Signaling.
    MBio. 2018 Nov 6;9(6). pii: e01465-18. doi: 10.1128/mBio.01465-18.

    Rother M, Gonzalez E, Teixeira da Costa AR, Wask L, Gravenstein I, Pardo M, Pietzke M, Gurumurthy RK, Angermann J, Laudeley R, Glage S, Meyer M, Chumduri C, Kempa S, Dinkel K, Unger A, Klebl B, Klos A, Meyer TF.
    Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection.
    Cell Host Microbe. 2018 May 9;23(5):661-671.e8. doi: 10.1016/j.chom.2018.04.002. Epub 2018 Apr 26.

    Müller A, Gillissen B, Richter A, Richter A, Chumduri C, Daniel PT, Scholz CW.
    Pan-class I  PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
    Cell Death Dis. 2018 Mar 7;9(3):384. doi: 10.1038/s41419-018-0413-4.

    Chumduri C, Gurumurthy RK, Zietlow R, Meyer TF.
    Subversion of host genome integrity by bacterial pathogens.
    Nat Rev Mol Cell Biol. 2016 Oct;17(10):659-73. doi: 10.1038/nrm.2016.100.

    Chumduri C, Gillissen B, Richter A, Richter A, Milojkovic A, Overkamp T, Müller A, Pott C, Daniel PT.
    Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.
    J Mol Med (Berl). 2015 May;93(5):559-72. doi: 10.1007/s00109-014-1242-2.

    Gurumurthy RK, Chumduri C, Karlas A, Kimmig S, Gonzalez E, Machuy N, Rudel T, Meyer TF.
    Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development.
    Mol Microbiol. 2014 Oct;94(1):186-201. doi: 10.1111/mmi.12751.

    Chumduri C, Gurumurthy RK, Zadora PK, Mi Y, Meyer TF.
    Chlamydia infection promotes host DNA damage and proliferation but impairs the DNA damage response.
    Cell Host Microbe. 2013 Jun 12;13(6):746-58. doi: 10.1016/j.chom.2013.05.010.

    Milojkovic A, Hemmati PG, Müer A, Overkamp T, Chumduri C, Jänicke RU, Gillissen B, Daniel PT.
    p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.
    Int J Cancer. 2013 Dec 1;133(11):2551-62. doi: 10.1002/ijc.28279.

    Müller A, Zang C, Chumduri C, Dörken B, Daniel PT, Scholz CW.
    Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
    Int J Cancer. 2013 Oct 15;133(8):1813-24. doi: 10.1002/ijc.28206.