2022[ to top ]
  • Shirakashi, R., Sisario, D., Taban, D., Korsa, T., Wanner, S.B., Neubauer, J., Djuzenova, C.S., Zimmermann, H., Sukhorukov, V.L.: Contraction of the rigor actomyosin complex drives bulk hemoglobin expulsion from hemolyzing erythrocytes. Biomechanics and Modeling in Mechanobiology. (2022).
  • La Greca, M., Chen, J.-L., Schubert, L., Kozuch, J., Berneiser, T., Terpitz, U., Heberle, J., Schlesinger, R.: The Photoreaction of the Proton-Pumping Rhodopsin 1 From the Maize Pathogenic Basidiomycete Ustilago maydis. Frontiers in Molecular Biosciences. 9, (2022).
  • Lu, J., Dreyer, I., Dickinson, M.S., Panzer, S., Jaslan, D., Navarro-Retamal, C., Geiger, D., Terpitz, U., Becker, D., Stroud, R.M., Marten, I., Hedrich, R.: Vicia faba TPC1, a genetically encoded variant of the vacuole Two Pore Channel 1, is hyperexcitable. bioRxiv. 2021.12.22.473873- (2022).
  • Halder, L.D., Babych, S., Palme, D.I., Mansouri-Ghahnavieh, E., Ivanov, L., Ashonibare, V., Langenhorst, D., Prusty, B., Rambach, G., Wich, M., Trinks, N., Blango, M.G., Kornitzer, D., Terpitz, U., Speth, C., Jungnickel, B., Beyersdorf, N., Zipfel, P.F., Brakhage, A.A., Skerka, C., Lorenz, M.: Candida albicans Induces Cross-Kingdom miRNA Trafficking in Human Monocytes To Promote Fungal Growth. mBio. 13, e03563–21 (2022).
2021[ to top ]
  • Fernández-Orth, J., Rolfes, L., Gola, L., Bittner, S., Andronic, J., Sukhorukov, V.L., Sisario, D., Landgraf, P., Dieterich, D.C., Cerina, M., Smalla, K.-H., Kähne, T., Budde, T., Kovac, S., Ruck, T., Sauer, M., Meuth, S.G.: A role for TASK2 channels in the human immunological synapse. European Journal of Immunology. 51, 342–353 (2021).
  • Fink, J., Schumacher, F., Schlegel, J., Stenzel, P., Wigger, D., Sauer, M., Kleuser, B., Seibel, J.: Azidosphinganine enables metabolic labeling and detection of sphingolipid de novo synthesis. Org. Biomol. Chem. 19, 2203–2212 (2021).
  • Panzer, S., Zhang, C., Konte, T., Bräuer, C., Diemar, A., Yogendran, P., Yu-Strzelczyk, J., Nagel, G., Gao, S., Terpitz, U.: Modified Rhodopsins From Aureobasidium pullulans Excel With Very High Proton-Transport Rates. Frontiers in Molecular Biosciences. 8, (2021).
  • Peters, S., Kaiser, L., Fink, J., Schumacher, F., Perschin, V., Schlegel, J., Sauer, M., Stigloher, C., Kleuser, B., Seibel, J., Schubert-Unkmeir, A.: Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria. Scientific Reports. 11, 4300- (2021).
  • Trinks, N., Reinhard, S., Drobny, M., Heilig, L., Löffler, J., Sauer, M., Terpitz, U.: Subdiffraction-resolution fluorescence imaging of immunological synapse formation between NK cells and A. fumigatus by expansion microscopy. Communications Biology. 4, 1151- (2021).
  • Djuzenova, C.S., Fischer, T., Katzer, A., Sisario, D., Korsa, T., Steussloff, G., Sukhorukov, V.L., Flentje, M.: Opposite effects of the triple target (DNA-PK/PI3K/mTOR) inhibitor PI-103 on the radiation sensitivity of glioblastoma cell lines proficient and deficient in DNA-PKcs. BMC Cancer. 21, 1201- (2021).
  • Schubert, J., Schulze, A., Prodromou, C., Neuweiler, H.: Two-colour single-molecule photoinduced electron transfer fluorescence imaging microscopy of chaperone dynamics. Nature Communications. 12, 6964- (2021).
  • Johe, P., Jung, S., Endres, E., Kersten, C., Zimmer, C., Ye, W., Sönnichsen, C., Hellmich, U.A., Sotriffer, C., Schirmeister, T., Neuweiler, H.: Warhead Reactivity Limits the Speed of Inhibition of the Cysteine Protease Rhodesain. ACS Chem. Biol. 16, 661–670 (2021).
  • Johé, P., Jaenicke, E., Neuweiler, H., Schirmeister, T., Kersten, C., Hellmich, U.A.: Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes. Journal of Biological Chemistry. 296, 100565- (2021).
  • Brych, A., Haas, F.B., Parzefall, K., Panzer, S., Schermuly, J., Altmüller, J., Engelsdorf, T., Terpitz, U., Rensing, S.A., Kiontke, S., Batschauer, A.: Coregulation of gene expression by White collar 1 and phytochrome in Ustilago maydis. Fungal Genetics and Biology. 103570- (2021).
  • Yu, Y., Wolf, A.-K., Thusek, S., Heinekamp, T., Bromley, M., Krappmann, S., Terpitz, U., Voigt, K., Brakhage, A.A., Beilhack, A.: Direct Visualization of Fungal Burden in Filamentous Fungus-Infected Silkworms, (2021).
  • Rajab, S., Bismin, L., Schwarze, S., Pinggera, A., Greger, I.H., Neuweiler, H.: Allosteric coupling of sub-millisecond clamshell motions in ionotropic glutamate receptor ligand-binding domains. Communications Biology. 4, 1056- (2021).
  • Lehmann, J., Jørgensen, M.E., Fratz, S., Müller, H.M., Kusch, J., Scherzer, S., Navarro-Retamal, C., Mayer, D., Böhm, J., Konrad, K.R., Terpitz, U., Dreyer, I., Mueller, T.D., Sauer, M., Hedrich, R., Geiger, D., Maierhofer, T.: Acidosis-induced activation of anion channel SLAH3 in the flooding-related stress response of Arabidopsis. Current Biology. (2021).
  • Zwettler, F.U., Reinhard, S., Sauer, M.: Chapter 15 - Ex-dSTORM and automated quantitative image analysis of expanded filamentous structures. In: Guichard, P. und Hamel, V. (hrsg.) Expansion Microscopy for Cell Biology. S. 317–340. Academic Press (2021).
  • Beliu, G., Altrichter, S., Guixà-González, R., Hemberger, M., Brauer, I., Dahse, A.-K., Scholz, N., Wieduwild, R., Kuhlemann, A., Batebi, H., Seufert, F., Pérez-Hernández, G., Hildebrand, P.W., Sauer, M., Langenhan, T.: Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain. Molecular Cell. 81, 905–921.e5 (2021).
  • Pauli, M., Paul, M.M., Proppert, S., Mrestani, A., Sharifi, M., Repp, F., Kürzinger, L., Kollmannsberger, P., Sauer, M., Heckmann, M., Sirén, A.-L.: Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections. Communications Biology. 4, 407- (2021).
  • Hassan, M.I.A., Keller, M., Hillger, M., Binder, U., Reuter, S., Herold, K., Telagathoti, A., Dahse, H.-M., Wicht, S., Trinks, N., Nietzsche, S., Deckert-Gaudig, T., Deckert, V., Mrowka, R., Terpitz, U., {Peter Saluz}, H., Voigt, K.: The impact of episporic modification of Lichtheimia corymbifera on virulence and interaction with phagocytes. Computational and Structural Biotechnology Journal. 19, 880–896 (2021).
  • Schulte, C., Khayenko, V., Nordblom, N.F., Tippel, F., Peck, V., Gupta, A.J., Maric, H.M.: High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale. iScience. 24, 101898- (2021).
  • Moreno-Yruela, C., Bæk, M., Vrsanova, A.-E., Schulte, C., Maric, H.M., Olsen, C.A.: Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases. Nature Communications. 12, 62- (2021).
  • Bartling, C.R.O., Jensen, T.M.T., Henry, S.M., Colliander, A.L., Sereikaite, V., Wenzler, M., Jain, P., Maric, H.M., Harpsøe, K., Pedersen, S.W., Clemmensen, L.S., Haugaard-Kedström, L.M., Gloriam, D.E., Ho, A., Strømgaard, K.: Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation. J. Am. Chem. Soc. 143, 891–901 (2021).
  • Jansch, C., Ziegler, G.C., Forero, A., Gredy, S., Wäldchen, S., Vitale, M.R., Svirin, E., Zöller, J.E.M., Waider, J., Günther, K., Edenhofer, F., Sauer, M., Wischmeyer, E., Lesch, K.-P.: Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. Journal of Neural Transmission. 128, 225–241 (2021).
  • García-Guerrero, E., Götz, R., Doose, S., Sauer, M., Rodríguez-Gil, A., Nerreter, T., Kortüm, K.M., Pérez-Simón, J.A., Einsele, H., Hudecek, M., Danhof, S.: Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab. Leukemia. 35, 201–214 (2021).
  • Schulte, C., Maric, H.M.: Expanding GABAAR pharmacology via receptor-associated proteins. Current Opinion in Pharmacology. 57, 98–106 (2021).
  • Haack, S., Baiker, S., Schlegel, J., Sauer, M., Sparwasser, T., Langenhorst, D., Beyersdorf, N.: Superagonistic CD28 stimulation induces IFN-γ release from mouse T helper 1 cells in vitro and in vivo. European Journal of Immunology. 51, 738–741 (2021).
  • Schlegel, J., Sauer, M.: Superresolution Microscopy of Sphingolipids. Lipid Rafts: Methods and Protocols. S. 303–311. Springer US, New York, NY (2021).
  • Helmerich, D.A., Beliu, G., Matikonda, S.S., Schnermann, M.J., Sauer, M.: Photoblueing of organic dyes can cause artifacts in super-resolution microscopy. Nature Methods. 18, 253–257 (2021).
  • Sputh, S., Panzer, S., Stigloher, C., Terpitz, U.: Superaufgelöste Mikroskopie: Pilze unter Beobachtung. BIOspektrum. 27, 380–382 (2021).
2020[ to top ]
  • Rozario, A.M., Zwettler, F., Duwé, S., Hargreaves, R.B., Brice, A., Dedecker, P., Sauer, M., Moseley, G.W., Whelan, D.R., Bell, T.D.M.: ‘Live and Large’: Super-Resolution Optical Fluctuation Imaging (SOFI) and Expansion Microscopy (ExM) of Microtubule Remodelling by Rabies Virus P Protein. Aust. J. Chem. (2020).
  • Götz, R., Kunz, T.C., Fink, J., Solger, F., Schlegel, J., Seibel, J., Kozjak-Pavlovic, V., Rudel, T., Sauer, M.: Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy. Nature Communications. 11, 6173- (2020).
  • Weiss, E., Schlegel, J., Terpitz, U., Weber, M., Linde, J., Schmitt, A.-L., Hünniger, K., Marischen, L., Gamon, F., Bauer, J., Löffler, C., Kurzai, O., Morton, C.O., Sauer, M., Einsele, H., Loeffler, J.: Reconstituting NK Cells After Allogeneic Stem Cell Transplantation Show Impaired Response to the Fungal Pathogen Aspergillus fumigatus. Frontiers in Immunology. 11, (2020).
  • Goretzki, B., Heiby, J.C., Hacker, C., Neuweiler, H., Hellmich, U.A.: NMR assignments of a dynamically perturbed and dimerization inhibited N-terminal domain variant of a spider silk protein from E. australis. Biomolecular NMR Assignments. 14, 67–71 (2020).
  • Matikonda, S.S., Götz, R., McLaughlin, R., Sauer, M., Schnermann, M.J.: Chapter Ten - Conformationally restrained pentamethine cyanines and use in reductive single molecule localization microscopy. In: Chenoweth, D.M. (hrsg.) Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods. S. 225–244. Academic Press (2020).
  • Kouhestani, D., Geis, M., Alsouri, S., Bumm, T.G.P., Einsele, H., Sauer, M., Stuhler, G.: Variant signaling topology at the cancer cell–T-cell interface induced by a two-component T-cell engager. Cellular & Molecular Immunology. (2020).
  • Volz, J., Kusch, C., Beck, S., Popp, M., Vögtle, T., Meub, M., Scheller, I., Heil, H.S., Preu, J., Schuhmann, M.K., Hemmen, K., Premsler, T., Sickmann, A., Heinze, K.G., Stegner, D., Stoll, G., Braun, A., Sauer, M., Nieswandt, B.: BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. The Journal of Clinical Investigation. 130, 6064–6079 (2020).
  • Andreska, T., Rauskolb, S., Schukraft, N., Lüningschrör, P., Sasi, M., Signoret-Genest, J., Behringer, M., Blum, R., Sauer, M., Tovote, P., Sendtner, M.: Induction of BDNF Expression in Layer II/III and Layer V Neurons of the Motor Cortex Is Essential for Motor Learning. J. Neurosci. 40, 6289- (2020).
  • Forero, A., Ku, H.-P., Malpartida, A.B., Wäldchen, S., Alhama-Riba, J., Kulka, C., Aboagye, B., Norton, W.H., Young, A.M., Ding, Y.-Q., Blum, R., Sauer, M., Rivero, O., Lesch, K.-P.: Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Neuropharmacology. 168, 108018- (2020).
  • Gründl, M., Walz, S., Hauf, L., Schwab, M., Werner, K.M., Spahr, S., Schulte, C., Maric, H.M., Ade, C.P., Gaubatz, S.: Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLOS Genetics. 16, e1008818- (2020).
  • Helmerich, D.A., Beliu, G., Sauer, M.: Multiple-Labeled Antibodies Behave Like Single Emitters in Photoswitching Buffer. ACS Nano. (2020).
  • Zwettler, F.U., Spindler, M.-C., Reinhard, S., Klein, T., Kurz, A., Benavente, R., Sauer, M.: Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy. Nature Communications. 11, 3222- (2020).
  • Memmel, S., Sisario, D., Zimmermann, H., Sauer, M., Sukhorukov, V.L., Djuzenova, C.S., Flentje, M.: FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy. BMC Bioinformatics. 21, 27- (2020).
  • Zwettler, F.U., Reinhard, S., Gambarotto, D., Bell, T.D.M., Hamel, V., Guichard, P., Sauer, M.: Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM). Nature Communications. 11, 3388- (2020).
  • Kunz, T.C., Götz, R., Gao, S., Sauer, M., Kozjak-Pavlovic, V.: Using Expansion Microscopy to Visualize and Characterize the Morphology of Mitochondrial Cristae. Frontiers in Cell and Developmental Biology. 8, 617- (2020).
  • Wäldchen, F., Schlegel, J., Götz, R., Luciano, M., Schnermann, M., Doose, S., Sauer, M.: Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM. Nature Communications. 11, 887- (2020).
  • Beliu, G., Sauer, M.: A Trojan Horse for live-cell super-resolution microscopy. Light: Science & Applications. 9, 2- (2020).
  • Götz, R., Panzer, S., Trinks, N., Eilts, J., Wagener, J., Turrà, D., Di Pietro, A., Sauer, M., Terpitz, U.: Expansion Microscopy for Cell Biology Analysis in Fungi. Frontiers in Microbiology. 11, (2020).
  • Siddig, S., Aufmkolk, S., Doose, S., Jobin, M.-L., Werner, C., Sauer, M., Calebiro, D.: Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones. Sci Adv. 6, eaay7193- (2020).
  • Prieto-Garcia, C., Hartmann, O., Reissland, M., Braun, F., Fischer, T., Walz, S., Schülein-Völk, C., Eilers, U., Ade, C.P., Calzado, M.A., Orian, A., Maric, H.M., Münch, C., Rosenfeldt, M., Eilers, M., Diefenbacher, M.E.: Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells. EMBO Molecular Medicine. 12, e11101- (2020).
  • Langlhofer, G., Schaefer, N., Maric, H.M., Keramidas, A., Zhang, Y., Baumann, P., Blum, R., Breitinger, U., Strømgaard, K., Schlosser, A., Kessels, M.M., Koch, D., Qualmann, B., Breitinger, H.-G., Lynch, J.W., Villmann, C.: A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition. J. Neurosci. 40, 4954- (2020).
  • Thiele, J.C., Helmerich, D.A., Oleksiievets, N., Tsukanov, R., Butkevich, E., Sauer, M., Nevskyi, O., Enderlein, J.: Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy. ACS Nano. 14, 14190–14200 (2020).
2019[ to top ]
  • Reinhard, S., Aufmkolk, S., Sauer, M., Doose, S.: Registration and Visualization of Correlative Super-Resolution Microscopy Data. Biophysical Journal. 116, 2073–2078 (2019).
  • Doll, S., Freitas, F.P., Shah, R., Aldrovandi, M., da Silva, M.C., Ingold, I., Grocin, A.G., Xavier da Silva, T.N., Panzilius, E., Scheel, C.H., Mourão, A., Buday, K., Sato, M., Wanninger, J., Vignane, T., Mohana, V., Rehberg, M., Flatley, A., Schepers, A., Kurz, A., White, D., Sauer, M., Sattler, M., Tate, E.W., Schmitz, W., Schulze, A., O’Donnell, V., Proneth, B., Popowicz, G.M., Pratt, D.A., Angeli, J.P.F., Conrad, M.: FSP1 is a glutathione-independent ferroptosis suppressor. Nature. 575, 693–698 (2019).
  • Nerreter, T., Letschert, S., Götz, R., Doose, S., Danhof, S., Einsele, H., Sauer, M., Hudecek, M.: Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nature Communications. 10, 3137- (2019).
  • Gambarotto, D., Zwettler, F.U., Le Guennec, M., Schmidt-Cernohorska, M., Fortun, D., Borgers, S., Heine, J., Schloetel, J.-G., Reuss, M., Unser, M., Boyden, E.S., Sauer, M., Hamel, V., Guichard, P.: Imaging cellular ultrastructures using expansion microscopy (U-ExM). Nature Methods. 16, 71–74 (2019).
  • Djuzenova, C.S., Fiedler, V., Memmel, S., Katzer, A., Sisario, D., Brosch, P.K., Göhrung, A., Frister, S., Zimmermann, H., Flentje, M., Sukhorukov, V.L.: Differential effects of the Akt inhibitor MK-2206 on migration and radiation sensitivity of glioblastoma cells. BMC Cancer. 19, 299- (2019).
  • Heiby, J.C., Goretzki, B., Johnson, C.M., Hellmich, U.A., Neuweiler, H.: Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk. Nature Communications. 10, 4378- (2019).
  • Banaszek, A., Bumm, T.G.P., Nowotny, B., Geis, M., Jacob, K., Wölfl, M., Trebing, J., Kucka, K., Kouhestani, D., Gogishvili, T., Krenz, B., Lutz, J., Rasche, L., Hönemann, D., Neuweiler, H., Heiby, J.C., Bargou, R.C., Wajant, H., Einsele, H., Riethmüller, G., Stuhler, G.: On-target restoration of a split T cell-engaging antibody for precision immunotherapy. Nature Communications. 10, 5387- (2019).
  • Schlegel, J., Peters, S., Doose, S., Schubert-Unkmeir, A., Sauer, M.: Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites. Frontiers in Cell and Developmental Biology. 7, 194- (2019).
  • Schurr, Y., Sperr, A., Volz, J., Beck, S., Reil, L., Kusch, C., Eiring, P., Bryson, S., Sauer, M., Nieswandt, B., Machesky, L., Bender, M.: Platelet lamellipodium formation is not required for thrombus formation and stability. Blood. 134, 2318–2329 (2019).
  • Kunz, T.C., Götz, R., Sauer, M., Rudel, T.: Detection of Chlamydia Developmental Forms and Secreted Effectors by Expansion Microscopy. Frontiers in Cellular and Infection Microbiology. 9, 276- (2019).
  • Derakhshani, S., Kurz, A., Japtok, L., Schumacher, F., Pilgram, L., Steinke, M., Kleuser, B., Sauer, M., Schneider-Schaulies, S., Avota, E.: Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium. Frontiers in Immunology. 10, 1294- (2019).
  • Schermelleh, L., Ferrand, A., Huser, T., Eggeling, C., Sauer, M., Biehlmaier, O., Drummen, G.P.C.: Super-resolution microscopy demystified. Nature Cell Biology. 21, 72–84 (2019).
  • Mercier, R., Wolmarans, A., Schubert, J., Neuweiler, H., Johnson, J.L., LaPointe, P.: The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation. Nature Communications. 10, 1273- (2019).
  • Zilkowski, I., Ziouti, F., Schulze, A., Hauck, S., Schmidt, S., Mainz, L., Sauer, M., Albrecht, K., Jundt, F., Groll, J.: Nanogels Enable Efficient miRNA Delivery and Target Gene Downregulation in Transfection-Resistant Multiple Myeloma Cells. Biomacromolecules. 20, 916–926 (2019).
  • Brühlmann, D., Vuillemin, T., Satwekar, A., Galano, E., Palmese, A., D’Angelo, A., Manco, Z., Souquet, J., Broly, H., Sauer, M., Hemberger, J., Jordan, M.: Generation of site-distinct N-glycan variants for in vitro bioactivity testing. Biotechnology and Bioengineering. 116, 1017–1028 (2019).
  • Panzer, S., Brych, A., Batschauer, A., Terpitz, U.: Opsin 1 and Opsin 2 of the Corn Smut Fungus Ustilago maydis Are Green Light-Driven Proton Pumps. Frontiers in Microbiology. 10, (2019).
  • Khayenko, V., Maric, H.M.: Targeting GABAAR-Associated Proteins: New Modulators, Labels and Concepts. Frontiers in Molecular Neuroscience. 12, 162- (2019).
  • Peters, S., Schlegel, J., Becam, J., Avota, E., Sauer, M., Schubert-Unkmeir, A.: Neisseria meningitidis Type IV Pili Trigger Ca2+-Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels. Infect. Immun. 87, e00410–19 (2019).
  • Baluapuri, A., Hofstetter, J., Dudvarski Stankovic, N., Endres, T., Bhandare, P., Vos, S.M., Adhikari, B., Schwarz, J.D., Narain, A., Vogt, M., Wang, S.-Y., Düster, R., Jung, L.A., Vanselow, J.T., Wiegering, A., Geyer, M., Maric, H.M., Gallant, P., Walz, S., Schlosser, A., Cramer, P., Eilers, M., Wolf, E.: MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Molecular Cell. 74, 674–687.e11 (2019).
  • Kasaragod, V.B., Hausrat, T.J., Schaefer, N., Kuhn, M., Christensen, N.R., Tessmer, I., Maric, H.M., Madsen, K.L., Sotriffer, C., Villmann, C., Kneussel, M., Schindelin, H.: Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron. 101, 673–689.e11 (2019).
  • Sdelci, S., Rendeiro, A.F., Rathert, P., You, W., Lin, J.-M.G., Ringler, A., Hofstätter, G., Moll, H.P., Gürtl, B., Farlik, M., Schick, S., Klepsch, F., Oldach, M., Buphamalai, P., Schischlik, F., Májek, P., Parapatics, K., Schmidl, C., Schuster, M., Penz, T., Buckley, D.L., Hudecz, O., Imre, R., Wang, S.-Y., Maric, H.M., Kralovics, R., Bennett, K.L., Müller, A.C., Mechtler, K., Menche, J., Bradner, J.E., Winter, G.E., Klavins, K., Casanova, E., Bock, C., Zuber, J., Kubicek, S.: MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation. Nature Genetics. 51, 990–998 (2019).
  • Beliu, G., Kurz, A.J., Kuhlemann, A.C., Behringer-Pliess, L., Meub, M., Wolf, N., Seibel, J., Shi, Z.-D., Schnermann, M., Grimm, J.B., Lavis, L.D., Doose, S., Sauer, M.: Bioorthogonal labeling with tetrazine-dyes for super-resolution microscopy. Communications Biology. 2, 261- (2019).
2018[ to top ]
  • Heil, H.S., Schreiber, B., Götz, R., Emmerling, M., Dabauvalle, M.-C., Krohne, G., Höfling, S., Kamp, M., Sauer, M., Heinze, K.G.: Sharpening emitter localization in front of a tuned mirror. Light: Science & Applications. 7, 99- (2018).
  • Börtlein, C., Draeger, A., Schoenauer, R., Kuhlemann, A., Sauer, M., Schneider-Schaulies, S., Avota, E.: The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling. Frontiers in Immunology. 9, 815- (2018).
  • Neubert, F., Beliu, G., Terpitz, U., Werner, C., Geis, C., Sauer, M., Doose, S.: Bioorthogonal Click Chemistry Enables Site-specific Fluorescence Labeling of Functional NMDA Receptors for Super-Resolution Imaging. Angewandte Chemie International Edition. 57, 16364–16369 (2018).
  • Tauscher, S., Nakagawa, H., Völker, K., Werner, F., Krebes, L., Potapenko, T., Doose, S., Birkenfeld, A.L., Baba, H.A., Kuhn, M.: β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice. Cardiovascular Diabetology. 17, 103 (2018).
  • Rat, C., Heiby, J.C., Bunz, J.P., Neuweiler, H.: Two-step self-assembly of a spider silk molecular clamp. Nature Communications. 9, 4779- (2018).
  • Sisario, D., Memmel, S., Doose, S., Neubauer, J., Zimmermann, H., Flentje, M., Djuzenova, C.S., Sauer, M., Sukhorukov, V.L.: Nanostructure of DNA repair foci revealed by superresolution microscopy. The FASEB Journal. fj.201701435- (2018).
  • Grabenbauer, F., Katzer, A., Sisario, D., Memmel, S., Flentje, M., Sukhorukov, V.L., Djuzenova, C.S.: MEK-inhibitor PD184352 enhances the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922: the role of cell type and drug-irradiation schedule. Oncotarget. 9, 37379–37392 (2018).
  • Adam, A., Deimel, S., Pardo-Medina, J., García-Martínez, J., Konte, T., Limón, M., Avalos, J., Terpitz, U.: Protein Activity of the Fusarium fujikuroi Rhodopsins CarO and OpsA and Their Relation to Fungus–Plant Interaction. International Journal of Molecular Sciences. 19, 215 (2018).
  • Brunk, M., Sputh, S., Doose, S., van de Linde, S., Terpitz, U.: HyphaTracker: An ImageJ toolbox for time-resolved analysis of spore germination in filamentous fungi. Scientific Reports. 8, 605- (2018).
  • Haselmann, H., Mannara, F., Werner, C., Planagumà, J., Miguez-Cabello, F., Schmidl, L., Grünewald, B., Petit-Pedrol, M., Kirmse, K., Classen, J., Demir, F., Klöcker, N., Soto, D., Doose, S., Dalmau, J., Hallermann, S., Geis, C.: Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction. Neuron. 100, 91–105.e9 (2018).
  • Bleem, A., Christiansen, G., Madsen, D.J., Maric, H., Strømgaard, K., Bryers, J.D., Daggett, V., Meyer, R.L., Otzen, D.E.: Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms. Journal of Molecular Biology. 430, 3751–3763 (2018).
  • Hines, R.M., Maric, H.M., Hines, D.J., Modgil, A., Panzanelli, P., Nakamura, Y., Nathanson, A.J., Cross, A., Deeb, T., Brandon, N.J., Davies, P., Fritschy, J.-M., Schindelin, H., Moss, S.J.: Developmental seizures and mortality result from reducing GABAA receptor α2-subunit interaction with collybistin. Nature Communications. 9, 3130- (2018).
2017[ to top ]
  • Büchel, G., Carstensen, A., Mak, K.-Y., Roeschert, I., Leen, E., Sumara, O., Hofstetter, J., Herold, S., Kalb, J., Baluapuri, A., Poon, E., Kwok, C., Chesler, L., Maric, H.M., Rickman, D.S., Wolf, E., Bayliss, R., Walz, S., Eilers, M.: Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle. Cell Reports. 21, 3483–3497 (2017).
  • Walter, T., Schlegel, J., Burgert, A., Kurz, A., Seibel, J., Sauer, M.: Incorporation studies of clickable ceramides in Jurkat cell plasma membranes. Chem. Commun. 53, 6836–6839 (2017).
  • Brühlmann, D., Sokolov, M., Butté, A., Sauer, M., Hemberger, J., Souquet, J., Broly, H., Jordan, M.: Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality. Biotechnology and Bioengineering. 114, 1448–1458 (2017).
  • Forero, A., Rivero, O., Wäldchen, S., Ku, H.-P., Kiser, D.P., Gärtner, Y., Pennington, L.S., Waider, J., Gaspar, P., Jansch, C., Edenhofer, F., Resink, T.J., Blum, R., Sauer, M., Lesch, K.-P.: Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Frontiers in Cellular Neuroscience. 11, 307- (2017).
  • Scholz, N., Guan, C., Nieberler, M., Grotemeyer, A., Maiellaro, I., Gao, S., Beck, S., Pawlak, M., Sauer, M., Asan, E., Rothemund, S., Winkler, J., Prömel, S., Nagel, G., Langenhan, T., Kittel, R.J.: Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. eLife. 6, e28360- (2017).
  • Michie, M.S., Götz, R., Franke, C., Bowler, M., Kumari, N., Magidson, V., Levitus, M., Loncarek, J., Sauer, M., Schnermann, M.J.: Cyanine Conformational Restraint in the Far-Red Range. J. Am. Chem. Soc. 139, 12406–12409 (2017).
  • Ziegler, S., Weiss, E., Schmitt, A.-L., Schlegel, J., Burgert, A., Terpitz, U., Sauer, M., Moretta, L., Sivori, S., Leonhardt, I., Kurzai, O., Einsele, H., Loeffler, J.: CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells. Scientific Reports. 7, 6138- (2017).
  • Lukeš, T., Glatzová, D., Kvíčalová, Z., Levet, F., Benda, A., Letschert, S., Sauer, M., Brdička, T., Lasser, T., Cebecauer, M.: Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging. Nature Communications. 8, 1731- (2017).
  • Sauer, M., Heilemann, M.: Single-Molecule Localization Microscopy in Eukaryotes. Chem. Rev. (2017).
  • Burgert, A., Schlegel, J., Bécam, J., Doose, S., Bieberich, E., Schubert-Unkmeir, A., Sauer, M.: Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy. Angewandte Chemie. (2017).
  • Memmel, S., Sisario, D., Zöller, C., Fiedler, V., Katzer, A., Heiden, R., Becker, N., Eing, L., Ferreira, F.L., Zimmermann, H., Sauer, M., Flentje, M., Sukhorukov, V.L., Djuzenova, C.S.: Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and Hsp90-inhibition of glioblastoma cells with different invasive capacities. Oncotarget. 8, 45298–45310 (2017).
  • Heiby, J.C., Rajab, S., Rat, C., Johnson, C.M., Neuweiler, H.: Conservation of folding and association within a family of spidroin N-terminal domains. Scientific Reports. 7, 16789 (2017).
  • Maric, H.M., Hausrat, T.J., Neubert, F., Dalby, N.O., Doose, S., Sauer, M., Kneussel, M., Strømgaard, K.: Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission. Nature Chemical Biology. 13, 153- (2017).
  • Brühlmann, D., Muhr, A., Parker, R., Vuillemin, T., Bucsella, B., Kalman, F., Torre, S., La Neve, F., Lembo, A., Haas, T., Sauer, M., Souquet, J., Broly, H., Hemberger, J., Jordan, M.: Cell culture media supplemented with raffinose reproducibly enhances high mannose glycan formation. Journal of Biotechnology. 252, 32–42 (2017).
  • Markert, S.M., Bauer, V., Muenz, T.S., Jones, N.G., Helmprobst, F., Britz, S., Sauer, M., Rössler, W., Engstler, M., Stigloher, C.: Chapter 2 - 3D subcellular localization with superresolution array tomography on ultrathin sections of various species. In: Müller-Reichert, T. und Verkade, P. (hrsg.) Correlative Light and Electron Microscopy III. S. 21–47. Academic Press (2017).
2016[ to top ]
  • Franke, C., Sauer, M., van de Linde, S.: Photometry unlocks 3D information from 2D localization microscopy data. Nat Meth. advance online publication, (2016).
  • Niehorster, T., Loschberger, A., Gregor, I., Kramer, B., Rahn, H.-J., Patting, M., Koberling, F., Enderlein, J., Sauer, M.: Multi-target spectrally resolved fluorescence lifetime imaging microscopy. Nat Meth. advance online publication, (2016).
  • Djuzenova, C., Fiedler, V., Katzer, A., Michel, K., Deckert, S., Zimmermann, H., Sukhorukov, V., Flentje, M.: Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule. Oncotarget. 5, (2016).
  • Konte, T., Terpitz, U., Plemenitas, A.: Reconstruction of the high-osmolarity glycerol (HOG) signaling pathway from the halophilic fungus Wallemia ichthyophaga in Saccharomyces cerevisiae. Frontiers in Microbiology. 7, (2016).
  • Schulze, A., Beliu, G., Helmerich, D.A., Schubert, J., Pearl, L.H., Prodromou, C., Neuweiler, H.: Cooperation of local motions in the Hsp90 molecular chaperone ATPase mechanism. Nat Chem Biol. advance online publication, (2016).
  • Yadav, P., Selvaraj, B.T., Bender, F.L.P., Behringer, M., Moradi, M., Sivadasan, R., Dombert, B., Blum, R., Asan, E., Sauer, M., Julien, J.-P., Sendtner, M.: Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathologica. 132, 93–110 (2016).
  • Dugar, G., Svensson, S.L., Bischler, T., Wäldchen, S., Reinhardt, R., Sauer, M., Sharma, C.M.: The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni. Nature Communications. 7, 11667- (2016).
  • Collenburg, L., Walter, T., Burgert, A., Müller, N., Seibel, J., Japtok, L., Kleuser, B., Sauer, M., Schneider-Schaulies, S.: A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells. The Journal of Immunology. 196, 3951–3962 (2016).
  • Mateos-Gil, P., Letschert, S., Doose, S., Sauer, M.: Super-resolution imaging of plasma membrane proteins with click chemistry. Frontiers in Cell and Developmental Biology. 4, 98- (2016).
  • Feldbauer, K., Schlegel, J., Weissbecker, J., Sauer, F., Wood, P.G., Bamberg, E., Terpitz, U.: Optochemokine Tandem for Light-Control of Intracellular Ca2+. PLoS ONE. 11, e0165344- (2016).
  • Markert, S.M., Britz, S., Proppert, S., Lang, M., Witvliet, D., Mulcahy, B., Sauer, M., Zhen, M., Bessereau, J.-L., Stigloher, C.: Filling the gap: adding super-resolution to array tomography for correlated ultrastructural and molecular identification of electrical synapses at the C. elegans connectome. Neurophotonics. 3, 041802–041802 (2016).
  • Jung, L.A., Gebhardt, A., Koelmel, W., Ade, C.P., Walz, S., Kuper, J., von Eyss, B., Letschert, S., Redel, C., d’Artista, L., Biankin, A., Zender, L., Sauer, M., Wolf, E., Evan, G., Kisker, C., Eilers, M.: OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene. 36, 1911- (2016).
  • Alexander, M., Sebastian, L., Elisabeth, M., Markus, S., Jürgen, S.: Synthesis and application of water-soluble, photoswitchable cyanine dyes for bioorthogonal labeling of cell-surface carbohydrates, https://www.degruyter.com/view/j/znc.2016.71.issue-9-10/znc-2016-0123/znc-2016-0123.xml, (2016).
  • Cheng, J., Sahani, S., Hausrat, T., Yang, J.-W., Ji, H., Schmarowski, N., Endle, H., Liu, X., Li, Y., Böttche, R., Radyushkin, K., Maric, H., Hoerder-Suabedissen, A., Molnár, Z., Prouvot, P.-H., Trimbuch, T., Ninnemann, O., Huai, J., Fan, W., Visentin, B., Sabbadini, R., Strømgaard, K., Stroh, A., Luhmann, H., Kneussel, M., Nitsch, R., Vogt, J.: Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling. Neuron. 92, 126–142 (2016).
  • Maric, H.M., Hausrat, T.J., Neubert, F., Dalby, N.O., Doose, S., Sauer, M., Kneussel, M., Strømgaard, K.: Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission. Nature Chemical Biology. 13, 153- (2016).
  • Werner, C., Pauli, M., Doose, S., Weishaupt, A., Haselmann, H., Grünewald, B., Sauer, M., Heckmann, M., Toyka, K.V., Asan, E., Sommer, C., Geis, C.: Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition. Brain. 139, 365–379 (2016).
2015[ to top ]
  • Hennig, S., van de Linde, S., Bergmann, S., Huser, T., Sauer, M.: Quantitative Super-Resolution Microscopy of Nanopipette-Deposited Fluorescent Patterns. ACS Nano. 9, 8122–8130 (2015).