Priv.-Doz. Dr. Sören Doose



List of publications

2021[ to top ]
  • García-Guerrero, E., Götz, R., Doose, S., Sauer, M., Rodríguez-Gil, A., Nerreter, T., Kortüm, K.M., Pérez-Simón, J.A., Einsele, H., Hudecek, M., Danhof, S.: Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab. Leukemia. 35, 201–214 (2021).
2020[ to top ]
  • Wäldchen, F., Schlegel, J., Götz, R., Luciano, M., Schnermann, M., Doose, S., Sauer, M.: Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM. Nature Communications. 11, 887- (2020).
  • Siddig, S., Aufmkolk, S., Doose, S., Jobin, M.-L., Werner, C., Sauer, M., Calebiro, D.: Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones. Sci Adv. 6, eaay7193- (2020).
2019[ to top ]
  • Schlegel, J., Peters, S., Doose, S., Schubert-Unkmeir, A., Sauer, M.: Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites. Frontiers in Cell and Developmental Biology. 7, 194- (2019).
  • Nerreter, T., Letschert, S., Götz, R., Doose, S., Danhof, S., Einsele, H., Sauer, M., Hudecek, M.: Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nature Communications. 10, 3137- (2019).
  • Beliu, G., Kurz, A.J., Kuhlemann, A.C., Behringer-Pliess, L., Meub, M., Wolf, N., Seibel, J., Shi, Z.-D., Schnermann, M., Grimm, J.B., Lavis, L.D., Doose, S., Sauer, M.: Bioorthogonal labeling with tetrazine-dyes for super-resolution microscopy. Communications Biology. 2, 261- (2019).
  • Reinhard, S., Aufmkolk, S., Sauer, M., Doose, S.: Registration and Visualization of Correlative Super-Resolution Microscopy Data. Biophysical Journal. 116, 2073–2078 (2019).
2018[ to top ]
  • Neubert, F., Beliu, G., Terpitz, U., Werner, C., Geis, C., Sauer, M., Doose, S.: Bioorthogonal Click Chemistry Enables Site-specific Fluorescence Labeling of Functional NMDA Receptors for Super-Resolution Imaging. Angewandte Chemie International Edition. 57, 16364–16369 (2018).
  • Brunk, M., Sputh, S., Doose, S., van de Linde, S., Terpitz, U.: HyphaTracker: An ImageJ toolbox for time-resolved analysis of spore germination in filamentous fungi. Scientific Reports. 8, 605- (2018).
  • Sisario, D., Memmel, S., Doose, S., Neubauer, J., Zimmermann, H., Flentje, M., Djuzenova, C.S., Sauer, M., Sukhorukov, V.L.: Nanostructure of DNA repair foci revealed by superresolution microscopy. The FASEB Journal. fj.201701435- (2018).
  • Haselmann, H., Mannara, F., Werner, C., Planagumà, J., Miguez-Cabello, F., Schmidl, L., Grünewald, B., Petit-Pedrol, M., Kirmse, K., Classen, J., Demir, F., Klöcker, N., Soto, D., Doose, S., Dalmau, J., Hallermann, S., Geis, C.: Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction. Neuron. 100, 91–105.e9 (2018).
  • Tauscher, S., Nakagawa, H., Völker, K., Werner, F., Krebes, L., Potapenko, T., Doose, S., Birkenfeld, A.L., Baba, H.A., Kuhn, M.: β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice. Cardiovascular Diabetology. 17, 103 (2018).
2017[ to top ]
  • Maric, H.M., Hausrat, T.J., Neubert, F., Dalby, N.O., Doose, S., Sauer, M., Kneussel, M., Strømgaard, K.: Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission. Nature Chemical Biology. 13, 153- (2017).
  • Burgert, A., Schlegel, J., Bécam, J., Doose, S., Bieberich, E., Schubert-Unkmeir, A., Sauer, M.: Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy. Angewandte Chemie. (2017).
2016[ to top ]
  • Werner, C., Pauli, M., Doose, S., Weishaupt, A., Haselmann, H., Grünewald, B., Sauer, M., Heckmann, M., Toyka, K.V., Asan, E., Sommer, C., Geis, C.: Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition. Brain. 139, 365–379 (2016).
  • Mateos-Gil, P., Letschert, S., Doose, S., Sauer, M.: Super-resolution imaging of plasma membrane proteins with click chemistry. Frontiers in Cell and Developmental Biology. 4, 98- (2016).
2015[ to top ]
  • Burgert, A., Letschert, S., Doose, S., Sauer, M.: Artifacts in single-molecule localization microscopy. Histochemistry and Cell Biology. 144, 123–131 (2015).
2014[ to top ]
  • Letschert, S., Göhler, A., Franke, C., Bertleff-Zieschang, N., Memmel, E., Doose, S., Seibel, J., Sauer, M.: Super-Resolution Imaging of Plasma Membrane Glycans. Angewandte Chemie International Edition. n/a-n/a (2014).
2013[ to top ]
  • Steger, K., Bollmann, S., Noe, F., Doose, S.: Systematic evaluation of fluorescence correlation spectroscopy data analysis on the nanosecond time scale. Phys. Chem. Chem. Phys. - (2013).
  • Seibel, J., König, S., Göhler, A., Doose, S., Memmel, E., Bertleff, N., Sauer, M.: Investigating infection processes with a workflow from organic chemistry to biophysics: the combination of metabolic glycoengineering, super-resolution fluorescence imaging and proteomics. Expert Rev Proteomics. 10, 25–31 (2013).
  • Schäfer, P., van de Linde, S., Lehmann, J., Sauer, M., Doose, S.: Methylene blue- and thiol-based oxygen depletion for super-resolution imaging. Analytical Chemistry. 85, 3393–3400 (2013).
2012[ to top ]
  • Yahiatène, I., Doose, S., Huser, T., Sauer, M.: Correlation-Matrix Analysis of Two-Color Coincidence Events in Single-Molecule Fluorescence Experiments. Analytical Chemistry. 84, 2729–2736 (2012).
  • Göhler, A., Büchner, C., André, S., Doose, S., Kaltner, H., Gabius, H.-J.: Analysis of homodimeric avian and human galectins by two methods based on fluorescence spectroscopy: Different structural alterations upon oxidation and ligand binding. Biochimie. 94, 2649–2655 (2012).
2011[ to top ]
  • Noe, F., Doose, S., Daidone, I., Löllmann, M., Sauer, M., Chodera, J.D., Smith, J.C.: Dynamical fingerprints for probing individual relaxation processes in biomolecular dynamics with simulations and kinetic experiments. Proceedings of the National Academy of Sciences. (2011).
  • van de Linde, S., Krstic, I., Prisner, T., Doose, S., Heilemann, M., Sauer, M.: Photoinduced formation of reversible dye radicals and their impact on super-resolution imaging. Photochem. Photobiol. Sci. 10, 499–506 (2011).
  • Bollmann, S., Lollmann, M., Sauer, M., Doose, S.: Dimer formation of organic fluorophores reports on biomolecular dynamics under denaturing conditions. Phys. Chem. Chem. Phys. 13, 12874–12882 (2011).
  • Bollmann, S., Burgert, A., Plattner, C., Nagel, L., Sewald, N., Löllmann, M., Sauer, M., Doose, S.: Conformational Flexibility of Glycosylated Peptides. ChemPhysChem. 12, 2907–2911 (2011).
  • Gohler, A., Buchner, C., Andre, S., Doose, S., Kaltner, H., Gabius, H.-J.: Sensing ligand binding to a clinically relevant lectin by tryptophan fluorescence anisotropy. Analyst. 136, 5270–5276 (2011).
2010[ to top ]
  • Daidone, I., Neuweiler, H., Doose, S., Sauer, M., Smith, J.C.: Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains. PLOS COMPUTATIONAL BIOLOGY. 6, (2010).
  • Goehler, A., Andre, S., Kaltner, H., Sauer, M., Gabius, H.-J., Doose, S.: Hydrodynamic Properties of Human Adhesion/Growth-Regulatory Galectins Studied by Fluorescence Correlation Spectroscopy. BIOPHYSICAL JOURNAL. 98, 3044–3053 (2010).
2009[ to top ]
  • Doose, S., Neuweiler, H., Sauer, M.: Fluorescence Quenching by Photoinduced Electron Transfer: A Reporter for Conformational Dynamics of Macromolecules. CHEMPHYSCHEM. 10, 1389–1398 (2009).
2008[ to top ]
  • Doose, S.: Importance of Backbone and Solvent Properties for Conformational Dynamics in Polypeptides. CHEMPHYSCHEM. 9, 2687–2689 (2008).
  • Goodman, R.P., Heilemann, M., Doose, S., Erben, C.M., Kapanidis, A.N., Turberfield, A.J.: Reconfigurable, braced, three-dimensional DNA nanostructures. NATURE NANOTECHNOLOGY. 3, 93–96 (2008).
  • Schuettpelz, M., Schoening, J.C., Doose, S., Neuweiler, H., Peters, E., Staiger, D., Sauer, M.: Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 130, 9507–9513 (2008).
2007[ to top ]
  • Doose, S.: Optical amplification from single excitons in collodial quantum dots. SMALL. 3, 1856–1858 (2007).
  • Doose, S., Neuweiler, H., Barsch, H., Sauer, M.: Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 104, 17400–17405 (2007).
  • Doose, S., Heilemann, M., Michalet, X., Weiss, S., Kapanidis, A.: Periodic acceptor excitation spectroscopy of single molecules. European Biophysics Journal. 36, 669–674 (2007).
  • Neuweiler, H., Lollmann, M., Doose, S., Sauer, M.: Dynamics of unfolded polypeptide chains in crowded environment studied by fluorescence correlation spectroscopy. JOURNAL OF MOLECULAR BIOLOGY. 365, 856–869 (2007).
  • Vogelsang, J., Doose, S., Sauer, M., Tinnefeld, P.: Single-Molecule Fluorescence Resonance Energy Transfer in Nanopipets: Improving Distance Resolution and Concentration Range. ANALYTICAL CHEMISTRY. 79, 7367–7375 (2007).
  • Doose, S., Barsch, H., Sauer, M.: Polymer properties of polythymine as revealed by translational diffusion. BIOPHYSICAL JOURNAL. 93, 1224–1234 (2007).
2006[ to top ]
  • Kim, J., Doose, S., Neuweiler, H., Sauer, M.: The initial step of DNA hairpin folding: a kinetic analysis using fluorescence correlation spectroscopy. NUCLEIC ACIDS RESEARCH. 34, 2516–2527 (2006).
  • Tsay, J., Doose, S., Weiss, S.: Rotational and translational diffusion of peptide-coated CdSe/CdS/ZnS nanorods studied by fluorescence correlation spectroscopy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 128, 1639–1647 (2006).
  • Pinaud, F., Michalet, X., Bentolila, L., Tsay, J., Doose, S., Li, J., Iyer, G., Weiss, S.: Advances in fluorescence imaging with quantum dot bio-probes. BIOMATERIALS. 27, 1679–1687 (2006).
2005[ to top ]
  • Neuweiler, H., Doose, S., Sauer, M.: A microscopic view of miniprotein folding: Enhanced folding efficiency through formation of an intermediate. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 102, 16650–16655 (2005).
  • Tsay, J., Doose, S., Pinaud, F., Weiss, S.: Enhancing the photoluminescence of peptide-coated nanocrystals with shell composition and UV irradiation. JOURNAL OF PHYSICAL CHEMISTRY B. 109, 1669–1674 (2005).
  • Michalet, X., Pinaud, F., Bentolila, L., Tsay, J., Doose, S., Li, J., Sundaresan, G., Wu, A., Gambhir, S., Weiss, S.: Quantum dots for live cells, in vivo imaging, and diagnostics. SCIENCE. 307, 538–544 (2005).
  • Kapanidis, A., Margeat, E., Laurence, T., Doose, S., Ho, S., Mukhopadhyay, J., Kortkhonjia, E., Mekler, V., Ebright, R., Weiss, S.: Retention of transcription initiation factor sigma(70) in transcription elongation: Single-molecule analysis. MOLECULAR CELL. 20, 347–356 (2005).
  • Doose, S., Tsay, J., Pinaud, F., Weiss, S.: Comparison of photophysical and colloidal properties of biocompatible semiconductor nanocrystals using fluorescence correlation spectroscopy. ANALYTICAL CHEMISTRY. 77, 2235–2242 (2005).
  • Doose, S., Neuweiler, H., Sauer, M.: A close look at fluorescence quenching of organic dyes by tryptophan. CHEMPHYSCHEM. 6, 2277–2285 (2005).
2004[ to top ]
  • Kapanidis, A., Lee, N., Laurence, T., Doose, S., Margeat, E., Weiss, S.: Fluorescence-aided molecule sorting: Analysis of structure and interactions by alternating-laser excitation of single molecules. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 101, 8936–8941 (2004).
2003[ to top ]
  • Michalet, X., Kapanidis, A., Laurence, T., Pinaud, F., Doose, S., Pflughoefft, M., Weiss, S.: The power and prospects of fluorescence microscopies and spectroscopies. ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE. 32, 161–182 (2003).