Prof. Dr. Markus Sauer

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+49 931 31-88687
m.sauer@uni-wuerzburg.de
Astrid Thal
+49 931 31-84507
+49 931 31-84509

Editorial boards
2015-presentHistochemistry and Cell Biology
2014-presentJournal of Structural Biology
2012-presentMethods in Applications in Fluorescence
2011-presentPLoS ONE

List of publications

2022[ to top ]
  • Brosch, P.K., Korsa, T., Taban, D., Eiring, P., Hildebrand, S., Neubauer, J., Zimmermann, H., Sauer, M., Shirakashi, R., Djuzenova, C.S., Sisario, D., Sukhorukov, V.L.: Glucose and Inositol Transporters, SLC5A1 and SLC5A3, in Glioblastoma Cell Migration. Cancers. 14, 5794 (2022).
2021[ to top ]
  • Beliu, G., Altrichter, S., Guixà-González, R., Hemberger, M., Brauer, I., Dahse, A.-K., Scholz, N., Wieduwild, R., Kuhlemann, A., Batebi, H., Seufert, F., Pérez-Hernández, G., Hildebrand, P.W., Sauer, M., Langenhan, T.: Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain. Molecular Cell. 81, 905–921.e5 (2021).
  • García-Guerrero, E., Götz, R., Doose, S., Sauer, M., Rodríguez-Gil, A., Nerreter, T., Kortüm, K.M., Pérez-Simón, J.A., Einsele, H., Hudecek, M., Danhof, S.: Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab. Leukemia. 35, 201–214 (2021).
  • Fernández-Orth, J., Rolfes, L., Gola, L., Bittner, S., Andronic, J., Sukhorukov, V.L., Sisario, D., Landgraf, P., Dieterich, D.C., Cerina, M., Smalla, K.-H., Kähne, T., Budde, T., Kovac, S., Ruck, T., Sauer, M., Meuth, S.G.: A role for TASK2 channels in the human immunological synapse. European Journal of Immunology. 51, 342–353 (2021).
  • Trinks, N., Reinhard, S., Drobny, M., Heilig, L., Löffler, J., Sauer, M., Terpitz, U.: Subdiffraction-resolution fluorescence imaging of immunological synapse formation between NK cells and A. fumigatus by expansion microscopy. Communications Biology. 4, 1151- (2021).
  • Schlegel, J., Sauer, M.: Superresolution Microscopy of Sphingolipids. Lipid Rafts: Methods and Protocols. S. 303–311. Springer US, New York, NY (2021).
  • Helmerich, D.A., Beliu, G., Matikonda, S.S., Schnermann, M.J., Sauer, M.: Photoblueing of organic dyes can cause artifacts in super-resolution microscopy. Nature Methods. 18, 253–257 (2021).
  • Haack, S., Baiker, S., Schlegel, J., Sauer, M., Sparwasser, T., Langenhorst, D., Beyersdorf, N.: Superagonistic CD28 stimulation induces IFN-γ release from mouse T helper 1 cells in vitro and in vivo. European Journal of Immunology. 51, 738–741 (2021).
  • Zwettler, F.U., Reinhard, S., Sauer, M.: Chapter 15 - Ex-dSTORM and automated quantitative image analysis of expanded filamentous structures. In: Guichard, P. und Hamel, V. (hrsg.) Expansion Microscopy for Cell Biology. S. 317–340. Academic Press (2021).
  • Pauli, M., Paul, M.M., Proppert, S., Mrestani, A., Sharifi, M., Repp, F., Kürzinger, L., Kollmannsberger, P., Sauer, M., Heckmann, M., Sirén, A.-L.: Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections. Communications Biology. 4, 407- (2021).
  • Jansch, C., Ziegler, G.C., Forero, A., Gredy, S., Wäldchen, S., Vitale, M.R., Svirin, E., Zöller, J.E.M., Waider, J., Günther, K., Edenhofer, F., Sauer, M., Wischmeyer, E., Lesch, K.-P.: Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. Journal of Neural Transmission. 128, 225–241 (2021).
  • Fink, J., Schumacher, F., Schlegel, J., Stenzel, P., Wigger, D., Sauer, M., Kleuser, B., Seibel, J.: Azidosphinganine enables metabolic labeling and detection of sphingolipid de novo synthesis. Org. Biomol. Chem. 19, 2203–2212 (2021).
  • Peters, S., Kaiser, L., Fink, J., Schumacher, F., Perschin, V., Schlegel, J., Sauer, M., Stigloher, C., Kleuser, B., Seibel, J., Schubert-Unkmeir, A.: Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria. Scientific Reports. 11, 4300- (2021).
  • Lehmann, J., Jørgensen, M.E., Fratz, S., Müller, H.M., Kusch, J., Scherzer, S., Navarro-Retamal, C., Mayer, D., Böhm, J., Konrad, K.R., Terpitz, U., Dreyer, I., Mueller, T.D., Sauer, M., Hedrich, R., Geiger, D., Maierhofer, T.: Acidosis-induced activation of anion channel SLAH3 in the flooding-related stress response of Arabidopsis. Current Biology. (2021).
2020[ to top ]
  • Zwettler, F.U., Reinhard, S., Gambarotto, D., Bell, T.D.M., Hamel, V., Guichard, P., Sauer, M.: Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM). Nature Communications. 11, 3388- (2020).
  • Helmerich, D.A., Beliu, G., Sauer, M.: Multiple-Labeled Antibodies Behave Like Single Emitters in Photoswitching Buffer. ACS Nano. (2020).
  • Thiele, J.C., Helmerich, D.A., Oleksiievets, N., Tsukanov, R., Butkevich, E., Sauer, M., Nevskyi, O., Enderlein, J.: Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy. ACS Nano. 14, 14190–14200 (2020).
  • Matikonda, S.S., Götz, R., McLaughlin, R., Sauer, M., Schnermann, M.J.: Chapter Ten - Conformationally restrained pentamethine cyanines and use in reductive single molecule localization microscopy. In: Chenoweth, D.M. (hrsg.) Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods. S. 225–244. Academic Press (2020).
  • Kouhestani, D., Geis, M., Alsouri, S., Bumm, T.G.P., Einsele, H., Sauer, M., Stuhler, G.: Variant signaling topology at the cancer cell–T-cell interface induced by a two-component T-cell engager. Cellular & Molecular Immunology. (2020).
  • Volz, J., Kusch, C., Beck, S., Popp, M., Vögtle, T., Meub, M., Scheller, I., Heil, H.S., Preu, J., Schuhmann, M.K., Hemmen, K., Premsler, T., Sickmann, A., Heinze, K.G., Stegner, D., Stoll, G., Braun, A., Sauer, M., Nieswandt, B.: BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. The Journal of Clinical Investigation. 130, 6064–6079 (2020).
  • Andreska, T., Rauskolb, S., Schukraft, N., Lüningschrör, P., Sasi, M., Signoret-Genest, J., Behringer, M., Blum, R., Sauer, M., Tovote, P., Sendtner, M.: Induction of BDNF Expression in Layer II/III and Layer V Neurons of the Motor Cortex Is Essential for Motor Learning. J. Neurosci. 40, 6289- (2020).
  • Weiss, E., Schlegel, J., Terpitz, U., Weber, M., Linde, J., Schmitt, A.-L., Hünniger, K., Marischen, L., Gamon, F., Bauer, J., Löffler, C., Kurzai, O., Morton, C.O., Sauer, M., Einsele, H., Loeffler, J.: Reconstituting NK Cells After Allogeneic Stem Cell Transplantation Show Impaired Response to the Fungal Pathogen Aspergillus fumigatus. Frontiers in Immunology. 11, (2020).
  • Kunz, T.C., Götz, R., Gao, S., Sauer, M., Kozjak-Pavlovic, V.: Using Expansion Microscopy to Visualize and Characterize the Morphology of Mitochondrial Cristae. Frontiers in Cell and Developmental Biology. 8, 617- (2020).
  • Memmel, S., Sisario, D., Zimmermann, H., Sauer, M., Sukhorukov, V.L., Djuzenova, C.S., Flentje, M.: FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy. BMC Bioinformatics. 21, 27- (2020).
  • Forero, A., Ku, H.-P., Malpartida, A.B., Wäldchen, S., Alhama-Riba, J., Kulka, C., Aboagye, B., Norton, W.H., Young, A.M., Ding, Y.-Q., Blum, R., Sauer, M., Rivero, O., Lesch, K.-P.: Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Neuropharmacology. 168, 108018- (2020).
  • Rozario, A.M., Zwettler, F., Duwé, S., Hargreaves, R.B., Brice, A., Dedecker, P., Sauer, M., Moseley, G.W., Whelan, D.R., Bell, T.D.M.: ‘Live and Large’: Super-Resolution Optical Fluctuation Imaging (SOFI) and Expansion Microscopy (ExM) of Microtubule Remodelling by Rabies Virus P Protein. Aust. J. Chem. (2020).
  • Zwettler, F.U., Spindler, M.-C., Reinhard, S., Klein, T., Kurz, A., Benavente, R., Sauer, M.: Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy. Nature Communications. 11, 3222- (2020).
  • Siddig, S., Aufmkolk, S., Doose, S., Jobin, M.-L., Werner, C., Sauer, M., Calebiro, D.: Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones. Sci Adv. 6, eaay7193- (2020).
  • Götz, R., Panzer, S., Trinks, N., Eilts, J., Wagener, J., Turrà, D., Di Pietro, A., Sauer, M., Terpitz, U.: Expansion Microscopy for Cell Biology Analysis in Fungi. Frontiers in Microbiology. 11, (2020).
  • Beliu, G., Sauer, M.: A Trojan Horse for live-cell super-resolution microscopy. Light: Science & Applications. 9, 2- (2020).
  • Wäldchen, F., Schlegel, J., Götz, R., Luciano, M., Schnermann, M., Doose, S., Sauer, M.: Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM. Nature Communications. 11, 887- (2020).
  • Götz, R., Kunz, T.C., Fink, J., Solger, F., Schlegel, J., Seibel, J., Kozjak-Pavlovic, V., Rudel, T., Sauer, M.: Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy. Nature Communications. 11, 6173- (2020).
2019[ to top ]
  • Derakhshani, S., Kurz, A., Japtok, L., Schumacher, F., Pilgram, L., Steinke, M., Kleuser, B., Sauer, M., Schneider-Schaulies, S., Avota, E.: Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium. Frontiers in Immunology. 10, 1294- (2019).
  • Schermelleh, L., Ferrand, A., Huser, T., Eggeling, C., Sauer, M., Biehlmaier, O., Drummen, G.P.C.: Super-resolution microscopy demystified. Nature Cell Biology. 21, 72–84 (2019).
  • Reinhard, S., Aufmkolk, S., Sauer, M., Doose, S.: Registration and Visualization of Correlative Super-Resolution Microscopy Data. Biophysical Journal. 116, 2073–2078 (2019).
  • Brühlmann, D., Vuillemin, T., Satwekar, A., Galano, E., Palmese, A., D’Angelo, A., Manco, Z., Souquet, J., Broly, H., Sauer, M., Hemberger, J., Jordan, M.: Generation of site-distinct N-glycan variants for in vitro bioactivity testing. Biotechnology and Bioengineering. 116, 1017–1028 (2019).
  • Zilkowski, I., Ziouti, F., Schulze, A., Hauck, S., Schmidt, S., Mainz, L., Sauer, M., Albrecht, K., Jundt, F., Groll, J.: Nanogels Enable Efficient miRNA Delivery and Target Gene Downregulation in Transfection-Resistant Multiple Myeloma Cells. Biomacromolecules. 20, 916–926 (2019).
  • Peters, S., Schlegel, J., Becam, J., Avota, E., Sauer, M., Schubert-Unkmeir, A.: Neisseria meningitidis Type IV Pili Trigger Ca2+-Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels. Infect. Immun. 87, e00410–19 (2019).
  • Beliu, G., Kurz, A.J., Kuhlemann, A.C., Behringer-Pliess, L., Meub, M., Wolf, N., Seibel, J., Shi, Z.-D., Schnermann, M., Grimm, J.B., Lavis, L.D., Doose, S., Sauer, M.: Bioorthogonal labeling with tetrazine-dyes for super-resolution microscopy. Communications Biology. 2, 261- (2019).
  • Nerreter, T., Letschert, S., Götz, R., Doose, S., Danhof, S., Einsele, H., Sauer, M., Hudecek, M.: Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nature Communications. 10, 3137- (2019).
  • Gambarotto, D., Zwettler, F.U., Le Guennec, M., Schmidt-Cernohorska, M., Fortun, D., Borgers, S., Heine, J., Schloetel, J.-G., Reuss, M., Unser, M., Boyden, E.S., Sauer, M., Hamel, V., Guichard, P.: Imaging cellular ultrastructures using expansion microscopy (U-ExM). Nature Methods. 16, 71–74 (2019).
  • Schlegel, J., Peters, S., Doose, S., Schubert-Unkmeir, A., Sauer, M.: Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites. Frontiers in Cell and Developmental Biology. 7, 194- (2019).
  • Schurr, Y., Sperr, A., Volz, J., Beck, S., Reil, L., Kusch, C., Eiring, P., Bryson, S., Sauer, M., Nieswandt, B., Machesky, L., Bender, M.: Platelet lamellipodium formation is not required for thrombus formation and stability. Blood. 134, 2318–2329 (2019).
  • Kunz, T.C., Götz, R., Sauer, M., Rudel, T.: Detection of Chlamydia Developmental Forms and Secreted Effectors by Expansion Microscopy. Frontiers in Cellular and Infection Microbiology. 9, 276- (2019).
  • Doll, S., Freitas, F.P., Shah, R., Aldrovandi, M., da Silva, M.C., Ingold, I., Grocin, A.G., Xavier da Silva, T.N., Panzilius, E., Scheel, C.H., Mourão, A., Buday, K., Sato, M., Wanninger, J., Vignane, T., Mohana, V., Rehberg, M., Flatley, A., Schepers, A., Kurz, A., White, D., Sauer, M., Sattler, M., Tate, E.W., Schmitz, W., Schulze, A., O’Donnell, V., Proneth, B., Popowicz, G.M., Pratt, D.A., Angeli, J.P.F., Conrad, M.: FSP1 is a glutathione-independent ferroptosis suppressor. Nature. 575, 693–698 (2019).
2018[ to top ]
  • Neubert, F., Beliu, G., Terpitz, U., Werner, C., Geis, C., Sauer, M., Doose, S.: Bioorthogonal Click Chemistry Enables Site-specific Fluorescence Labeling of Functional NMDA Receptors for Super-Resolution Imaging. Angewandte Chemie International Edition. 57, 16364–16369 (2018).
  • Sisario, D., Memmel, S., Doose, S., Neubauer, J., Zimmermann, H., Flentje, M., Djuzenova, C.S., Sauer, M., Sukhorukov, V.L.: Nanostructure of DNA repair foci revealed by superresolution microscopy. The FASEB Journal. fj.201701435- (2018).
  • Börtlein, C., Draeger, A., Schoenauer, R., Kuhlemann, A., Sauer, M., Schneider-Schaulies, S., Avota, E.: The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling. Frontiers in Immunology. 9, 815- (2018).
  • Heil, H.S., Schreiber, B., Götz, R., Emmerling, M., Dabauvalle, M.-C., Krohne, G., Höfling, S., Kamp, M., Sauer, M., Heinze, K.G.: Sharpening emitter localization in front of a tuned mirror. Light: Science & Applications. 7, 99- (2018).
2017[ to top ]
  • Sauer, M., Heilemann, M.: Single-Molecule Localization Microscopy in Eukaryotes. Chem. Rev. (2017).
  • Forero, A., Rivero, O., Wäldchen, S., Ku, H.-P., Kiser, D.P., Gärtner, Y., Pennington, L.S., Waider, J., Gaspar, P., Jansch, C., Edenhofer, F., Resink, T.J., Blum, R., Sauer, M., Lesch, K.-P.: Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Frontiers in Cellular Neuroscience. 11, 307- (2017).
  • Scholz, N., Guan, C., Nieberler, M., Grotemeyer, A., Maiellaro, I., Gao, S., Beck, S., Pawlak, M., Sauer, M., Asan, E., Rothemund, S., Winkler, J., Prömel, S., Nagel, G., Langenhan, T., Kittel, R.J.: Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. eLife. 6, e28360- (2017).
  • Michie, M.S., Götz, R., Franke, C., Bowler, M., Kumari, N., Magidson, V., Levitus, M., Loncarek, J., Sauer, M., Schnermann, M.J.: Cyanine Conformational Restraint in the Far-Red Range. J. Am. Chem. Soc. 139, 12406–12409 (2017).
  • Brühlmann, D., Sokolov, M., Butté, A., Sauer, M., Hemberger, J., Souquet, J., Broly, H., Jordan, M.: Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality. Biotechnology and Bioengineering. 114, 1448–1458 (2017).
  • Brühlmann, D., Muhr, A., Parker, R., Vuillemin, T., Bucsella, B., Kalman, F., Torre, S., La Neve, F., Lembo, A., Haas, T., Sauer, M., Souquet, J., Broly, H., Hemberger, J., Jordan, M.: Cell culture media supplemented with raffinose reproducibly enhances high mannose glycan formation. Journal of Biotechnology. 252, 32–42 (2017).
  • Ziegler, S., Weiss, E., Schmitt, A.-L., Schlegel, J., Burgert, A., Terpitz, U., Sauer, M., Moretta, L., Sivori, S., Leonhardt, I., Kurzai, O., Einsele, H., Loeffler, J.: CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells. Scientific Reports. 7, 6138- (2017).
  • Markert, S.M., Bauer, V., Muenz, T.S., Jones, N.G., Helmprobst, F., Britz, S., Sauer, M., Rössler, W., Engstler, M., Stigloher, C.: Chapter 2 - 3D subcellular localization with superresolution array tomography on ultrathin sections of various species. In: Müller-Reichert, T. und Verkade, P. (hrsg.) Correlative Light and Electron Microscopy III. S. 21–47. Academic Press (2017).
  • Burgert, A., Schlegel, J., Bécam, J., Doose, S., Bieberich, E., Schubert-Unkmeir, A., Sauer, M.: Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy. Angewandte Chemie. (2017).
  • Memmel, S., Sisario, D., Zöller, C., Fiedler, V., Katzer, A., Heiden, R., Becker, N., Eing, L., Ferreira, F.L., Zimmermann, H., Sauer, M., Flentje, M., Sukhorukov, V.L., Djuzenova, C.S.: Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and Hsp90-inhibition of glioblastoma cells with different invasive capacities. Oncotarget. 8, 45298–45310 (2017).
  • Lukeš, T., Glatzová, D., Kvíčalová, Z., Levet, F., Benda, A., Letschert, S., Sauer, M., Brdička, T., Lasser, T., Cebecauer, M.: Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging. Nature Communications. 8, 1731- (2017).
  • Walter, T., Schlegel, J., Burgert, A., Kurz, A., Seibel, J., Sauer, M.: Incorporation studies of clickable ceramides in Jurkat cell plasma membranes. Chem. Commun. 53, 6836–6839 (2017).
  • Maric, H.M., Hausrat, T.J., Neubert, F., Dalby, N.O., Doose, S., Sauer, M., Kneussel, M., Strømgaard, K.: Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission. Nature Chemical Biology. 13, 153- (2017).
2016[ to top ]
  • Franke, C., Sauer, M., van de Linde, S.: Photometry unlocks 3D information from 2D localization microscopy data. Nat Meth. advance online publication, (2016).
  • Collenburg, L., Walter, T., Burgert, A., Müller, N., Seibel, J., Japtok, L., Kleuser, B., Sauer, M., Schneider-Schaulies, S.: A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells. The Journal of Immunology. 196, 3951–3962 (2016).
  • Markert, S.M., Britz, S., Proppert, S., Lang, M., Witvliet, D., Mulcahy, B., Sauer, M., Zhen, M., Bessereau, J.-L., Stigloher, C.: Filling the gap: adding super-resolution to array tomography for correlated ultrastructural and molecular identification of electrical synapses at the C. elegans connectome. Neurophotonics. 3, 041802–041802 (2016).
  • Dugar, G., Svensson, S.L., Bischler, T., Wäldchen, S., Reinhardt, R., Sauer, M., Sharma, C.M.: The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni. Nature Communications. 7, 11667- (2016).
  • Mateos-Gil, P., Letschert, S., Doose, S., Sauer, M.: Super-resolution imaging of plasma membrane proteins with click chemistry. Frontiers in Cell and Developmental Biology. 4, 98- (2016).
  • Yadav, P., Selvaraj, B.T., Bender, F.L.P., Behringer, M., Moradi, M., Sivadasan, R., Dombert, B., Blum, R., Asan, E., Sauer, M., Julien, J.-P., Sendtner, M.: Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathologica. 132, 93–110 (2016).
  • Alexander, M., Sebastian, L., Elisabeth, M., Markus, S., Jürgen, S.: Synthesis and application of water-soluble, photoswitchable cyanine dyes for bioorthogonal labeling of cell-surface carbohydrates, https://www.degruyter.com/view/j/znc.2016.71.issue-9-10/znc-2016-0123/znc-2016-0123.xml, (2016).
  • Jung, L.A., Gebhardt, A., Koelmel, W., Ade, C.P., Walz, S., Kuper, J., von Eyss, B., Letschert, S., Redel, C., d’Artista, L., Biankin, A., Zender, L., Sauer, M., Wolf, E., Evan, G., Kisker, C., Eilers, M.: OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene. 36, 1911- (2016).
  • Werner, C., Pauli, M., Doose, S., Weishaupt, A., Haselmann, H., Grünewald, B., Sauer, M., Heckmann, M., Toyka, K.V., Asan, E., Sommer, C., Geis, C.: Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition. Brain. 139, 365–379 (2016).
  • Niehorster, T., Loschberger, A., Gregor, I., Kramer, B., Rahn, H.-J., Patting, M., Koberling, F., Enderlein, J., Sauer, M.: Multi-target spectrally resolved fluorescence lifetime imaging microscopy. Nat Meth. advance online publication, (2016).
2015[ to top ]
  • Schücker, K., Holm, T., Franke, C., Sauer, M., Benavente, R.: Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution. Proceedings of the National Academy of Sciences. 112, 2029–2033 (2015).
  • Ehmann, N., Sauer, M., Kittel, R.J.: Super-resolution microscopy of the synaptic active zone. Frontiers in Cellular Neuroscience. 9, (2015).
  • Schneider, J., Klein, T., Mielich-Süss, B., Koch, G., Franke, C., Kuipers, O.P., Kovács, Ákos T., Sauer, M., Lopez, D.: Spatio-temporal Remodeling of Functional Membrane Microdomains Organizes the Signaling Networks of a Bacterium. PLoS Genet. 11, e1005140- (2015).
  • Burgert, A., Letschert, S., Doose, S., Sauer, M.: Artifacts in single-molecule localization microscopy. Histochemistry and Cell Biology. 144, 123–131 (2015).
  • Hennig, S., van de Linde, S., Bergmann, S., Huser, T., Sauer, M.: Quantitative Super-Resolution Microscopy of Nanopipette-Deposited Fluorescent Patterns. ACS Nano. 9, 8122–8130 (2015).
  • Wäldchen, S., Lehmann, J., Klein, T., van de Linde, S., Sauer, M.: Light-induced cell damage in live-cell super-resolution microscopy. Scientific Reports. 5, 15348- (2015).
  • Grimm, J.B., Klein, T., Kopek, B.G., Shtengel, G., Hess, H.F., Sauer, M., Lavis, L.D.: Synthesis of a Far-Red Photoactivatable Silicon-Containing Rhodamine for Super-Resolution Microscopy. Angewandte Chemie. n/a-n/a (2015).
  • von Eyss, B., Jaenicke, L., Kortlever, R., Royla, N., Wiese, K., Letschert, S., McDuffus, L.-A., Sauer, M., Rosenwald, A., Evan, G., Kempa, S., Eilers, M.: A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer. Cancer Cell. 28, 743–757 (2015).
  • Andronic, J., Shirakashi, R., Pickel, S.U., Westerling, K.M., Klein, T., Holm, T., Sauer, M., Sukhorukov, V.L.: Hypotonic Activation of the Myo-Inositol Transporter SLC5A3 in HEK293 Cells Probed by Cell Volumetry, Confocal and Super-Resolution Microscopy. PLoS ONE. 10, e0119990 (2015).
  • Paul, M.M., Pauli, M., Ehmann, N., Hallermann, S., Sauer, M., Kittel, R.J., Heckmann, M.: Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation. Frontiers in Cellular Neuroscience. 9, (2015).
  • Brühlmann, D., Jordan, M., Hemberger, J., Sauer, M., Stettler, M., Broly, H.: Tailoring recombinant protein quality by rational media design. Biotechnology Progress. 31, 615–629 (2015).
  • Hennig, S., van de Linde, S., Lummer, M., Simonis, M., Huser, T., Sauer, M.: Instant Live-Cell Super-Resolution Imaging of Cellular Structures by Nanoinjection of Fluorescent Probes. Nano Lett. 15, 1374–1381 (2015).
  • Humpert, F., Yahiatène, I., Lummer, M., Sauer, M., Huser, T.: Quantifying molecular colocalization in live cell fluorescence microscopy. Journal of Biophotonics. 8, 124–132 (2015).
2014[ to top ]
  • Letschert, S., Göhler, A., Franke, C., Bertleff-Zieschang, N., Memmel, E., Doose, S., Seibel, J., Sauer, M.: Super-Resolution Imaging of Plasma Membrane Glycans. Angewandte Chemie International Edition. n/a-n/a (2014).
  • van de Linde, S., Sauer, M.: How to switch a fluorophore: from undesired blinking to controlled photoswitching. Chem. Soc. Rev. 2014. 43(4), 1076–1087 (2014).
  • Holm, T., Klein, T., Löschberger, A., Klamp, T., Wiebusch, G., van de Linde, S., Sauer, M.: A Blueprint for Cost-Efficient Localization Microscopy. ChemPhysChem. 15, 651–654 (2014).
  • Whelan, D.R., Holm, T., Sauer, M., Bell, T.D.M.: Focus on Super-Resolution Imaging with Direct Stochastic Optical Reconstruction Microscopy (dSTORM). Australian Journal of Chemistry. 67, 179–183 (2014).
  • Löschberger, A., Niehörster, T., Sauer, M.: Click chemistry for the conservation of cellular structures and fluorescent proteins: ClickOx. Biotechnology Journal. n/a-n/a (2014).
  • Andreska, T., Aufmkolk, S., Sauer, M., Blum, R.: High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons. Frontiers in Cellular Neuroscience. 8, (2014).
  • Mehlitz, A., Karunakaran, K., Herweg, J.-A., Krohne, G., van de Linde, S., Rieck, E., Sauer, M., Rudel, T.: The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress. Cellular Microbiology. n/a-n/a (2014).
  • Proppert, S., Wolter, S., Holm, T., Klein, T., van de Linde, S., Sauer, M.: Cubic B-spline calibration for 3D super-resolution measurements using astigmatic imaging. Opt. Express. 22, 10304–10316 (2014).
  • Ehmann, N., van de Linde, S., Alon, A., Ljaschenko, D., Keung, X.Z., Holm, T., Rings, A., DiAntonio, A., Hallermann, S., Ashery, U., Heckmann, M., Sauer, M., Kittel, R.J.: Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states. Nat Commun. 5, (2014).
  • Sauer, M., Neuweiler, H.: PET-FCS: Probing Rapid Structural Fluctuations of Proteins and Nucleic Acids by Single-Molecule Fluorescence Quenching. In: Engelborghs, Y. und Visser, A.J. (hrsg.) Methods Mol Biol - Fluorescence Spectroscopy and Microscopy. S. 597–615. Humana Press (2014).
  • Löschberger, A., Franke, C., Krohne, G., van de Linde, S., Sauer, M.: Correlative super-resolution fluorescence and electron microscopy of the nuclear pore complex with molecular resolution. Journal of Cell Science. 127, 4351–4355 (2014).
  • Sauer, M.: Timing Protein Assembly in Neurons. Chemistry & Biology. 21, 703–704 (2014).
  • Klein, T., Proppert, S., Sauer, M.: Eight years of single-molecule localization microscopy. Histochemistry and Cell Biology. 141, 561–575 (2014).
  • Bielopolski, N., Lam, A.D., Bar-On, D., Sauer, M., Stuenkel, E.L., Ashery, U.: Differential Interaction of Tomosyn with Syntaxin and SNAP25 Depends on Domains in the WD40 β-Propeller Core and Determines Its Inhibitory Activity. Journal of Biological Chemistry. 289, 17087–17099 (2014).
2013[ to top ]
  • Kolesinska, B., Podwysocka, D.J., Rueping, M.A., Seebach, D., Kamena, F., Walde, P., Sauer, M., Windschiegl, B., Meyer-Ács, M., Vor der Brüggen, M., Giehring, S.: Permeation through Phospholipid Bilayers, Skin-Cell Penetration, Plasma Stability, and CD Spectra of α- and β-Oligoproline Derivatives. Chemistry & Biodiversity. 10, 1–38 (2013).
  • van de Linde, S., Aufmkolk, S., Franke, C., Holm, T., Klein, T., Löschberger, A., Proppert, S., Wolter, S., Sauer, M.: Investigating Cellular Structures at the Nanoscale with Organic Fluorophores. Chemistry & Biology. 20, 8–18 (2013).
  • Seibel, J., König, S., Göhler, A., Doose, S., Memmel, E., Bertleff, N., Sauer, M.: Investigating infection processes with a workflow from organic chemistry to biophysics: the combination of metabolic glycoengineering, super-resolution fluorescence imaging and proteomics. Expert Rev Proteomics. 10, 25–31 (2013).
  • Andronic, J., Bobak, N., Bittner, S., Ehling, P., Kleinschnitz, C., Herrmann, A.M., Zimmermann, H., Sauer, M., Wiendl, H., Budde, T., Meuth, S.G., Sukhorukov, V.L.: Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828, 699–707 (2013).
  • Klamp, T., Camps, M., Nieto, B., Guasch, F., Ranasinghe, R.T., Wiedemann, J., Petrášek, Z., Schwille, P., Klenerman, D., Sauer, M.: Highly Rapid Amplification-Free and Quantitative DNA Imaging Assay. Sci. Rep. 3, (2013).
  • Sauer, M.: Localization microscopy coming of age: from concepts to biological impact. Journal of Cell Science. 126, 3505–3513 (2013).
  • Schäfer, P., van de Linde, S., Lehmann, J., Sauer, M., Doose, S.: Methylene blue- and thiol-based oxygen depletion for super-resolution imaging. Analytical Chemistry. 85, 3393–3400 (2013).
  • Wolf, A., Akrap, N., Marg, B., Galliardt, H., Heiligentag, M., Humpert, F., Sauer, M., Kaltschmidt, B., Kaltschmidt, C., Seidel, T.: Elements of Transcriptional Machinery Are Compatible among Plants and Mammals. PLOS ONE. 8, e53737- (2013).
  • Lummer, M., Humpert, F., Wiedenlübbert, M., Sauer, M., Schüttpelz, M., Staiger, D.: A New Set of Reversibly Photoswitchable Fluorescent Proteins for Use in Transgenic Plants. Molecular Plant. 6, 1518–1530 (2013).
2012[ to top ]
  • Dertinger, T., Colyer, R., Vogel, R., Heilemann, M., Sauer, M., Enderlein, J., Weiss, S.: Superresolution Optical Fluctuation Imaging (SOFI). Advances in Experimental Medicine and Biology. 733, 17–21 (2012).
  • Löschberger, A., van de Linde, S., Dabauvalle, M.-C., Rieger, B., Heilemann, M., Krohne, G., Sauer, M.: Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution. Journal of Cell Science. 125, 570–575 (2012).
  • van de Linde, S., Heilemann, M., Sauer, M.: Live-Cell Super-Resolution Imaging with Synthetic Fluorophores. Annual Review of Physical Chemistry. 63, null (2012).
  • Owen, D.M., Sauer, M., Gaus, K.: Fluorescence localization microscopy: The transition from concept to biological research tool. cib. 5, 0–1 (2012).
  • Bar-On, D., Wolter, S., van de Linde, S., Heilemann, M., Nudelman, G., Nachliel, E., Gutman, M., Sauer, M., Ashery, U.: Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters. Journal of Biological Chemistry. (2012).
  • WOLTER, S., SAUER, M.: Follow-up to paper by S. Wolter, M. Schüttpelz, M. Tscherepanow, S. van de Linde, M. Heilemann and M. Sauer, entitled Real-Time Computation of Subdiffraction-Resolution Fluorescence Images. Journal of Microscopy. 245, 109–109 (2012).
  • Terpitz, U., Letschert, S., Bonda, U., Spahn, C., Guan, C., Sauer, M., Zimmermann, U., Bamberg, E., Zimmermann, D., Sukhorukov, V.: Dielectric Analysis and Multi-cell Electrofusion of the Yeast Pichia pastoris for Electrophysiological Studies. Journal of Membrane Biology. 1–12 (2012).
  • Klein, T., van de Linde, S., Sauer, M.: Live-Cell Super-Resolution Imaging Goes Multicolor. ChemBioChem. 13, 1861–1863 (2012).
  • Wolter, S., Loschberger, A., Holm, T., Aufmkolk, S., Dabauvalle, M.-C., van de Linde, S., Sauer, M.: rapidSTORM: accurate, fast open-source software for localization microscopy. Nat Meth. 9, 1040–1041 (2012).
  • Lando, D., Endesfelder, U., Berger, H., Subramanian, L., Dunne, P.D., McColl, J., Klenerman, D., Carr, A.M., Sauer, M., Allshire, R.C., Heilemann, M., Laue, E.D.: Quantitative single-molecule microscopy reveals that CENP-ACnp1 deposition occurs during G2 in fission yeast. Open Biology. 2, (2012).
  • Yahiatène, I., Doose, S., Huser, T., Sauer, M.: Correlation-Matrix Analysis of Two-Color Coincidence Events in Single-Molecule Fluorescence Experiments. Analytical Chemistry. 84, 2729–2736 (2012).
2011[ to top ]
  • Klein, T., Loeschberger, A., Proppert, S., Wolter, S., van de Linde, S., Sauer, M.: Live-cell dSTORM with SNAP-tag fusion proteins. NATURE METHODS. 8, 7–9 (2011).
  • Noe, F., Doose, S., Daidone, I., Löllmann, M., Sauer, M., Chodera, J.D., Smith, J.C.: Dynamical fingerprints for probing individual relaxation processes in biomolecular dynamics with simulations and kinetic experiments. Proceedings of the National Academy of Sciences. (2011).
  • van de Linde, S., Loschberger, A., Klein, T., Heidbreder, M., Wolter, S., Heilemann, M., Sauer, M.: Direct stochastic optical reconstruction microscopy with standard fluorescent probes. Nat. Protocols. 6, 991–1009 (2011).