piwik-script

    Lehrstuhl für Biotechnologie und Biophysik

    Prof. Dr. Markus Sauer

    Telefon:
    E-Mail:
    Sekretariat:
    Telefon:
    Fax:

    +49 931 31-88687
    m.sauer@uni-wuerzburg.de
    Astrid Thal
    +49 931 31-84507
    +49 931 31-84509

    Editorial boards
    2015-presentHistochemistry and Cell Biology
    2014-presentJournal of Structural Biology
    2012-presentMethods in Applications in Fluorescence
    2011-presentPLoS ONE

    List of publications

    [ 2018 ] [ 2017 ] [ 2016 ] [ 2015 ] [ 2014 ] [ 2013 ] [ 2012 ] [ 2011 ] [ 2010 ] [ 2009 ] [ 2008 ] [ 2007 ] [ 2006 ] [ 2005 ] [ 2004 ] [ 2003 ] [ 2002 ] [ 2001 ] [ 2000 ] [ 1999 ] [ 1998 ] [ 1997 ] [ 1996 ] [ 1995 ] [ 1994 ] [ 1993 ]

    2018[ nach oben ]

    • Börtlein, C., Draeger, A., Schoenauer, R., Kuhlemann, A., Sauer, M., Schneider-Schaulies, S., Avota, E.: The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling.Frontiers in Immunology.9,815-- (2018).
       
    • Heil, H.S., Schreiber, B., Götz, R., Emmerling, M., Dabauvalle, M.-C., Krohne, G., Höfling, S., Kamp, M., Sauer, M., Heinze, K.G.: Sharpening emitter localization in front of a tuned mirror.Light: Science & Applications.7,99-- (2018).
       
    • Neubert, F., Beliu, G., Terpitz, U., Werner, C., Geis, C., Sauer, M., Doose, S.: Bioorthogonal Click Chemistry Enables Site-specific Fluorescence Labeling of Functional NMDA Receptors for Super-Resolution Imaging.Angewandte Chemie International Edition.57,16364--16369 (2018).
       
    • Sisario, D., Memmel, S., Doose, S., Neubauer, J., Zimmermann, H., Flentje, M., Djuzenova, C.S., Sauer, M., Sukhorukov, V.L.: Nanostructure of DNA repair foci revealed by superresolution microscopy.The FASEB Journal.fj.201701435-- (2018).
       

    2017[ nach oben ]

    • Forero, A., Rivero, O., Wäldchen, S., Ku, H.-P., Kiser, D.P., Gärtner, Y., Pennington, L.S., Waider, J., Gaspar, P., Jansch, C., Edenhofer, F., Resink, T.J., Blum, R., Sauer, M., Lesch, K.-P.: Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain.Frontiers in Cellular Neuroscience.11,307-- (2017).
       
    • Memmel, S., Sisario, D., Zöller, C., Fiedler, V., Katzer, A., Heiden, R., Becker, N., Eing, L., Ferreira, F.L.R., Zimmermann, H., Sauer, M., Flentje, M., Sukhorukov, V.L., Djuzenova, C.S.: Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and Hsp90-inhibition of glioblastoma cells with different invasive capacities.Oncotarget.8,45298–45310 (2017).
       
    • Walter, T., Schlegel, J., Burgert, A., Kurz, A., Seibel, J., Sauer, M.: Incorporation studies of clickable ceramides in Jurkat cell plasma membranes.Chem. Commun.53,6836--6839 (2017).
       
    • Markert, S.M., Bauer, V., Muenz, T.S., Jones, N.G., Helmprobst, F., Britz, S., Sauer, M., Rössler, W., Engstler, M., Stigloher, C.: Chapter 2 - 3D subcellular localization with superresolution array tomography on ultrathin sections of various species. In: Müller-Reichert, T. und Verkade, P. (hrsg.) Correlative Light and Electron Microscopy III. S. 21--47. Academic Press (2017).
       
    • Brühlmann, D., Muhr, A., Parker, R., Vuillemin, T., Bucsella, B., Kalman, F., Torre, S., La Neve, F., Lembo, A., Haas, T., Sauer, M., Souquet, J., Broly, H., Hemberger, J., Jordan, M.: Cell culture media supplemented with raffinose reproducibly enhances high mannose glycan formation.Journal of Biotechnology.252,32--42 (2017).
       
    • Michie, M.S., Götz, R., Franke, C., Bowler, M., Kumari, N., Magidson, V., Levitus, M., Loncarek, J., Sauer, M., Schnermann, M.J.: Cyanine Conformational Restraint in the Far-Red Range.J. Am. Chem. Soc.139,12406--12409 (2017).
       
    • Ziegler, S., Weiss, E., Schmitt, A.-L., Schlegel, J., Burgert, A., Terpitz, U., Sauer, M., Moretta, L., Sivori, S., Leonhardt, I., Kurzai, O., Einsele, H., Loeffler, J.: CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells.Scientific Reports.7,6138-- (2017).
       
    • Sauer, M., Heilemann, M.: Single-Molecule Localization Microscopy in Eukaryotes.Chem. Rev. (2017).
       
    • Burgert, A., Schlegel, J., Bécam, J., Doose, S., Bieberich, E., Schubert-Unkmeir, A., Sauer, M.: Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy.Angewandte Chemie. (2017).
       
    • Brühlmann, D., Sokolov, M., Butté, A., Sauer, M., Hemberger, J., Souquet, J., Broly, H., Jordan, M.: Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality.Biotechnology and Bioengineering.114,1448--1458 (2017).
       
    • Scholz, N., Guan, C., Nieberler, M., Grotemeyer, A., Maiellaro, I., Gao, S., Beck, S., Pawlak, M., Sauer, M., Asan, E., Rothemund, S., Winkler, J., Prömel, S., Nagel, G., Langenhan, T., Kittel, R.J.: Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons.eLife.6,e28360-- (2017).
       
    • Lukeš, T., Glatzová, D., Kvíčalová, Z., Levet, F., Benda, A., Letschert, S., Sauer, M., Brdička, T., Lasser, T., Cebecauer, M.: Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging.Nature Communications.8,1731-- (2017).
       
    • Maric, H.M., Hausrat, T.J., Neubert, F., Dalby, N.O., Doose, S., Sauer, M., Kneussel, M., Strømgaard, K.: Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission.Nature Chemical Biology.13,153-- (2017).
       

    2016[ nach oben ]

    • Franke, C., Sauer, M., van de Linde, S.: Photometry unlocks 3D information from 2D localization microscopy data.Nat Meth.advance online publication, (2016).
       
    • Mateos-Gil, P., Letschert, S., Doose, S., Sauer, M.: Super-resolution imaging of plasma membrane proteins with click chemistry.Frontiers in Cell and Developmental Biology.4,98-- (2016).
       
    • Markert, S.M., Britz, S., Proppert, S., Lang, M., Witvliet, D., Mulcahy, B., Sauer, M., Zhen, M., Bessereau, J.-L., Stigloher, C.: Filling the gap: adding super-resolution to array tomography for correlated ultrastructural and molecular identification of electrical synapses at the C. elegans connectome.Neurophotonics.3,041802--041802 (2016).
       
    • Dugar, G., Svensson, S.L., Bischler, T., Wäldchen, S., Reinhardt, R., Sauer, M., Sharma, C.M.: The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni.Nature Communications.7,11667-- (2016).
       
    • Yadav, P., Selvaraj, B.T., Bender, F.L.P., Behringer, M., Moradi, M., Sivadasan, R., Dombert, B., Blum, R., Asan, E., Sauer, M., Julien, J.-P., Sendtner, M.: Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling.Acta Neuropathologica.132,93--110 (2016).
       
    • Niehorster, T., Loschberger, A., Gregor, I., Kramer, B., Rahn, H.-J., Patting, M., Koberling, F., Enderlein, J., Sauer, M.: Multi-target spectrally resolved fluorescence lifetime imaging microscopy.Nat Meth.advance online publication, (2016).
       
    • Collenburg, L., Walter, T., Burgert, A., Müller, N., Seibel, J., Japtok, L., Kleuser, B., Sauer, M., Schneider-Schaulies, S.: A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells.The Journal of Immunology.196,3951--3962 (2016).
       
    • Werner, C., Pauli, M., Doose, S., Weishaupt, A., Haselmann, H., Grünewald, B., Sauer, M., Heckmann, M., Toyka, K.V., Asan, E., Sommer, C., Geis, C.: Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition.Brain.139,365--379 (2016).
       
    • Alexander, M., Sebastian, L., Elisabeth, M., Markus, S., Jürgen, S.: Synthesis and application of water-soluble, photoswitchable cyanine dyes for bioorthogonal labeling of cell-surface carbohydrates, https://www.degruyter.com/view/j/znc.2016.71.issue-9-10/znc-2016-0123/znc-2016-0123.xml, (2016).
       
    • Jung, L.A., Gebhardt, A., Koelmel, W., Ade, C.P., Walz, S., Kuper, J., von Eyss, B., Letschert, S., Redel, C., d'Artista, L., Biankin, A., Zender, L., Sauer, M., Wolf, E., Evan, G., Kisker, C., Eilers, M.: OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.Oncogene.36,1911-- (2016).
       

    2015[ nach oben ]

    • Andronic, J., Shirakashi, R., Pickel, S.U., Westerling, K.M., Klein, T., Holm, T., Sauer, M., Sukhorukov, V.L.: Hypotonic Activation of the Myo-Inositol Transporter SLC5A3 in HEK293 Cells Probed by Cell Volumetry, Confocal and Super-Resolution Microscopy.PLoS ONE.10,e0119990 (2015).
       
    • Ehmann, N., Sauer, M., Kittel, R.J.: Super-resolution microscopy of the synaptic active zone.Frontiers in Cellular Neuroscience.9, (2015).
       
    • Brühlmann, D., Jordan, M., Hemberger, J., Sauer, M., Stettler, M., Broly, H.: Tailoring recombinant protein quality by rational media design.Biotechnology Progress.31,615--629 (2015).
       
    • Humpert, F., Yahiatène, I., Lummer, M., Sauer, M., Huser, T.: Quantifying molecular colocalization in live cell fluorescence microscopy.Journal of Biophotonics.8,124--132 (2015).
       
    • von Eyss, B., Jaenicke, L. A., Kortlever, R. M., Royla, N., Wiese, K. E., Letschert, S., McDuffus, L.-A., Sauer, M., Rosenwald, A., Evan, G. I., Kempa, S., Eilers, M.: A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.Cancer Cell.28,743--757 (2015).
       
    • Grimm, J.B., Klein, T., Kopek, B.G., Shtengel, G., Hess, H.F., Sauer, M., Lavis, L.D.: Synthesis of a Far-Red Photoactivatable Silicon-Containing Rhodamine for Super-Resolution Microscopy.Angewandte Chemie.n/a--n/a (2015).
       
    • Wäldchen, S., Lehmann, J., Klein, T., van de Linde, S., Sauer, M.: Light-induced cell damage in live-cell super-resolution microscopy.Scientific Reports.5,15348-- (2015).
       
    • Hennig, S., van de Linde, S., Bergmann, S., Huser, T., Sauer, M.: Quantitative Super-Resolution Microscopy of Nanopipette-Deposited Fluorescent Patterns.ACS Nano.9,8122--8130 (2015).
       
    • Burgert, A., Letschert, S., Doose, S., Sauer, M.: Artifacts in single-molecule localization microscopy.Histochemistry and Cell Biology.144,123-131 (2015).
       
    • Schneider, J., Klein, T., Mielich-Süss, B., Koch, G., Franke, C., Kuipers, O.P., Kovács, Á.T., Sauer, M., Lopez, D.: Spatio-temporal Remodeling of Functional Membrane Microdomains Organizes the Signaling Networks of a Bacterium.PLoS Genet.11,e1005140-- (2015).
       
    • Paul, M.M., Pauli, M., Ehmann, N., Hallermann, S., Sauer, M., Kittel, R.J., Heckmann, M.: Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation.Frontiers in Cellular Neuroscience.9, (2015).
       
    • Hennig, S., van de Linde, S., Lummer, M., Simonis, M., Huser, T., Sauer, M.: Instant Live-Cell Super-Resolution Imaging of Cellular Structures by Nanoinjection of Fluorescent Probes.Nano Lett.15,1374--1381 (2015).
       
    • Schücker, K., Holm, T., Franke, C., Sauer, M., Benavente, R.: Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution.Proceedings of the National Academy of Sciences.112,2029-2033 (2015).
       

    2014[ nach oben ]

    • Letschert, S., Göhler, A., Franke, C., Bertleff-Zieschang, N., Memmel, E., Doose, S., Seibel, J., Sauer, M.: Super-Resolution Imaging of Plasma Membrane Glycans.Angewandte Chemie International Edition.n/a--n/a (2014).
       
    • Sauer, M., Neuweiler, H.: PET-FCS: Probing Rapid Structural Fluctuations of Proteins and Nucleic Acids by Single-Molecule Fluorescence Quenching. In: Engelborghs, Y. und Visser, A.J.W.G. (hrsg.) Methods Mol Biol - Fluorescence Spectroscopy and Microscopy. S. 597-615. Humana Press (2014).
       
    • Holm, T., Klein, T., Löschberger, A., Klamp, T., Wiebusch, G., van de Linde, S., Sauer, M.: A Blueprint for Cost-Efficient Localization Microscopy.ChemPhysChem.15,651--654 (2014).
       
    • Whelan, D.R., Holm, T., Sauer, M., Bell, T.D.M.: Focus on Super-Resolution Imaging with Direct Stochastic Optical Reconstruction Microscopy (dSTORM).Australian Journal of Chemistry.67,179-183 (2014).
       
    • Andreska, T., Aufmkolk, S., Sauer, M., Blum, R.: High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons.Frontiers in Cellular Neuroscience.8, (2014).
       
    • Mehlitz, A., Karunakaran, K., Herweg, J.-A., Krohne, G., van de Linde, S., Rieck, E., Sauer, M., Rudel, T.: The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress.Cellular Microbiology.n/a--n/a (2014).
       
    • Proppert, S., Wolter, S., Holm, T., Klein, T., van de Linde, S., Sauer, M.: Cubic B-spline calibration for 3D super-resolution measurements using astigmatic imaging.Opt. Express.22,10304--10316 (2014).
       
    • Ehmann, N., van de Linde, S., Alon, A., Ljaschenko, D., Keung, X.Z., Holm, T., Rings, A., DiAntonio, A., Hallermann, S., Ashery, U., Heckmann, M., Sauer, M., Kittel, R.J.: Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states.Nat Commun.5, (2014).
       
    • van de Linde, S., Sauer, M.: How to switch a fluorophore: from undesired blinking to controlled photoswitching.Chem. Soc. Rev. 2014.43(4),1076-1087 (2014).
       
    • Löschberger, A., Niehörster, T., Sauer, M.: Click chemistry for the conservation of cellular structures and fluorescent proteins: ClickOx.Biotechnology Journal.n/a--n/a (2014).
       
    • Löschberger, A., Franke, C., Krohne, G., van de Linde, S., Sauer, M.: Correlative super-resolution fluorescence and electron microscopy of the nuclear pore complex with molecular resolution.Journal of Cell Science.127,4351-4355 (2014).
       
    • Sauer, M.: Timing Protein Assembly in Neurons.Chemistry & Biology.21,703--704 (2014).
       
    • Bielopolski, N., Lam, A.D., Bar-On, D., Sauer, M., Stuenkel, E.L., Ashery, U.: Differential Interaction of Tomosyn with Syntaxin and SNAP25 Depends on Domains in the WD40 β-Propeller Core and Determines Its Inhibitory Activity.Journal of Biological Chemistry.289,17087-17099 (2014).
       
    • Klein, T., Proppert, S., Sauer, M.: Eight years of single-molecule localization microscopy.Histochemistry and Cell Biology.141,561--575 (2014).
       

    2013[ nach oben ]

    • Sauer, M.: Localization microscopy coming of age: from concepts to biological impact.Journal of Cell Science.126,3505-3513 (2013).
       
    • Kolesinska, B., Podwysocka, D.J., Rueping, M.A., Seebach, D., Kamena, F., Walde, P., Sauer, M., Windschiegl, B., Meyer-Ács, M., Vor der Brüggen, M., Giehring, S.: Permeation through Phospholipid Bilayers, Skin-Cell Penetration, Plasma Stability, and CD Spectra of α- and β-Oligoproline Derivatives.Chemistry & Biodiversity.10,1--38 (2013).
       
    • van de Linde, S., Aufmkolk, S., Franke, C., Holm, T., Klein, T., Löschberger, A., Proppert, S., Wolter, S., Sauer, M.: Investigating Cellular Structures at the Nanoscale with Organic Fluorophores.Chemistry & Biology.20,8 - 18 (2013).
       
    • Seibel, J., König, S., Göhler, A., Doose, S., Memmel, E., Bertleff, N., Sauer, M.: Investigating infection processes with a workflow from organic chemistry to biophysics: the combination of metabolic glycoengineering, super-resolution fluorescence imaging and proteomics.Expert Rev Proteomics.10,25--31 (2013).
       
    • Andronic, J., Bobak, N., Bittner, S., Ehling, P., Kleinschnitz, C., Herrmann, A.M., Zimmermann, H., Sauer, M., Wiendl, H., Budde, T., Meuth, S.G., Sukhorukov, V.L.: Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes.Biochimica et Biophysica Acta (BBA) - Biomembranes.1828,699 - 707 (2013).
       
    • Klamp, T., Camps, M., Nieto, B., Guasch, F., Ranasinghe, R.T., Wiedemann, J., Petrášek, Z., Schwille, P., Klenerman, D., Sauer, M.: Highly Rapid Amplification-Free and Quantitative DNA Imaging Assay.Sci. Rep.3, (2013).
       
    • Schäfer, P., van de Linde, S., Lehmann, J., Sauer, M., Doose, S.: Methylene blue- and thiol-based oxygen depletion for super-resolution imaging.Analytical Chemistry.85,3393 - 3400 (2013).
       
    • Lummer, M., Humpert, F., Wiedenlübbert, M., Sauer, M., Schüttpelz, M., Staiger, D.: A New Set of Reversibly Photoswitchable Fluorescent Proteins for Use in Transgenic Plants.Molecular Plant.6,1518--1530 (2013).
       
    • Wolf, A., Akrap, N., Marg, B., Galliardt, H., Heiligentag, M., Humpert, F., Sauer, M., Kaltschmidt, B., Kaltschmidt, C., Seidel, T.: Elements of Transcriptional Machinery Are Compatible among Plants and Mammals.PLOS ONE.8,e53737-- (2013).
       

    2012[ nach oben ]

    • Dertinger, T., Colyer, R., Vogel, R., Heilemann, M., Sauer, M., Enderlein, J., Weiss, S.: Superresolution Optical Fluctuation Imaging (SOFI).Advances in Experimental Medicine and Biology.733,17-21 (2012).
       
    • Terpitz, U., Letschert, S., Bonda, U., Spahn, C., Guan, C., Sauer, M., Zimmermann, U., Bamberg, E., Zimmermann, D., Sukhorukov, V.: Dielectric Analysis and Multi-cell Electrofusion of the Yeast Pichia pastoris for Electrophysiological Studies.Journal of Membrane Biology.1-12 (2012).
       
    • Löschberger, A., van de Linde, S., Dabauvalle, M.-C., Rieger, B., Heilemann, M., Krohne, G., Sauer, M.: Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution.Journal of Cell Science.125,570-575 (2012).
       
    • van de Linde, S., Heilemann, M., Sauer, M.: Live-Cell Super-Resolution Imaging with Synthetic Fluorophores.Annual Review of Physical Chemistry.63,null (2012).
       
    • Owen, D.M., Sauer, M., Gaus, K.: Fluorescence localization microscopy: The transition from concept to biological research tool.cib.5,0---1 (2012).
       
    • Bar-On, D., Wolter, S., van de Linde, S., Heilemann, M., Nudelman, G., Nachliel, E., Gutman, M., Sauer, M., Ashery, U.: Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters.Journal of Biological Chemistry. (2012).
       
    • WOLTER, S., SAUER, M.: Follow-up to paper by S. Wolter, M. Schüttpelz, M. Tscherepanow, S. van de Linde, M. Heilemann and M. Sauer, entitled Real-Time Computation of Subdiffraction-Resolution Fluorescence Images.Journal of Microscopy.245,109--109 (2012).
       
    • Klein, T., van de Linde, S., Sauer, M.: Live-Cell Super-Resolution Imaging Goes Multicolor.ChemBioChem.13,1861--1863 (2012).
       
    • Wolter, S., Loschberger, A., Holm, T., Aufmkolk, S., Dabauvalle, M.-C., van de Linde, S., Sauer, M.: rapidSTORM: accurate, fast open-source software for localization microscopy.Nat Meth.9,1040--1041 (2012).
       
    • Lando, D., Endesfelder, U., Berger, H., Subramanian, L., Dunne, P.D., McColl, J., Klenerman, D., Carr, A.M., Sauer, M., Allshire, R.C., Heilemann, M., Laue, E.D.: Quantitative single-molecule microscopy reveals that CENP-ACnp1 deposition occurs during G2 in fission yeast.Open Biology.2, (2012).
       
    • Yahiatène, I., Doose, S., Huser, T., Sauer, M.: Correlation-Matrix Analysis of Two-Color Coincidence Events in Single-Molecule Fluorescence Experiments.Analytical Chemistry.84,2729-2736 (2012).
       

    2011[ nach oben ]

    • van de Linde, S., Krstic, I., Prisner, T., Doose, S., Heilemann, M., Sauer, M.: Photoinduced formation of reversible dye radicals and their impact on super-resolution imaging.Photochem. Photobiol. Sci.10,499-506 (2011).
       
    • Klein, T., Loeschberger, A., Proppert, S., Wolter, S., van de Linde, S., Sauer, M.: Live-cell dSTORM with SNAP-tag fusion proteins.NATURE METHODS.8,7-9 (2011).
       
    • Kaminski Schierle, G.S., van de Linde, S., Erdelyi, M., Esbjörner, E.K., Klein, T., Rees, E., Bertoncini, C.W., Dobson, C.M., Sauer, M., Kaminski, C.F.: In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging.Journal of the American Chemical Society.133,12902-12905 (2011).
       
    • Wolter, S., Endesfelder, U., van de Linde, S., Heilemann, M., Sauer, M.: Measuring localization performance of super-resolution algorithms on very active samples.Optics Express.19,7020--33 (2011).
       
    • Vogel, B., Löschberger, A., Sauer, M., Hock, R.: Cross-linking of DNA through HMGA1 suggests a DNA scaffold.Nucleic Acids Research. (2011).
       
    • van de Linde, S., Loschberger, A., Klein, T., Heidbreder, M., Wolter, S., Heilemann, M., Sauer, M.: Direct stochastic optical reconstruction microscopy with standard fluorescent probes.Nat. Protocols.6,991--1009 (2011).
       
    • van de Linde, S., Wolter, S., Sauer, M.: Single-molecule Photoswitching and Localization.Aust. J. Chem.64,503--511 (2011).
       
    • Bollmann, S., Lollmann, M., Sauer, M., Doose, S.: Dimer formation of organic fluorophores reports on biomolecular dynamics under denaturing conditions.Phys. Chem. Chem. Phys.13,12874-12882 (2011).
       
    • Seefeldt, B., Altenhoner, K., Tosic, O., Geisler, T., Sauer, M., Mattay, J.: Kinetic studies on visible-light-switchable photochromic fluorophores based on diarylethenes.Photochem. Photobiol. Sci.10,1488--1495 (2011).
       
    • Bollmann, S., Burgert, A., Plattner, C., Nagel, L., Sewald, N., Löllmann, M., Sauer, M., Doose, S.: Conformational Flexibility of Glycosylated Peptides.ChemPhysChem.12,2907--2911 (2011).
       
    • Noe, F., Doose, S., Daidone, I., Löllmann, M., Sauer, M., Chodera, J.D., Smith, J.C.: Dynamical fingerprints for probing individual relaxation processes in biomolecular dynamics with simulations and kinetic experiments.Proceedings of the National Academy of Sciences. (2011).
       
    • Lummer, M., Humpert, F., Steuwe, C., Caesar, K., Schüttpelz, M., Sauer, M., Staiger, D.: Reversible Photoswitchable DRONPA-s Monitors Nucleocytoplasmic Transport of an RNA-Binding Protein in Transgenic Plants.Traffic.12,693--702 (2011).
       

    2010[ nach oben ]

    • Seidel, T., Seefeldt, B., Sauer, M., Dietz, K.-J.: In vivo analysis of the 2-Cys peroxiredoxin oligomeric state by two-step FRET.JOURNAL OF BIOTECHNOLOGY.149,272-279 (2010).
       
    • Wolter, S., Schuettpelz, M., Tscherepanow, M., van de Linde, S., Heilemann, M., Sauer, M.: Real-time computation of subdiffraction-resolution fluorescence images.JOURNAL OF MICROSCOPY-OXFORD.237,12-22 (2010).
       
    • Kottke, T., van de Linde, S., Sauer, M., Kakorin, S., Heilemann, M.: Identification of the Product of Photoswitching of an Oxazine Fluorophore Using Fourier Transform Infrared Difference Spectroscopy.The Journal of Physical Chemistry Letters.1,3156-3159 (2010).
       
    • Zheng, Z., Nottbohm, C.T., Turchanin, A., Muzik, H., Beyer, A., Heilemann, M., Sauer, M., Goelzhaeuser, A.: Janus Nanomembranes: A Generic Platform for Chemistry in Two Dimensions.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.49,8493-8497 (2010).
       
    • Dertinger, T., Heilemann, M., Vogel, R., Sauer, M., Weiss, S.: Superresolution Optical Fluctuation Imaging with Organic Dyes.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.49,9441-9443 (2010).
       
    • Daidone, I., Neuweiler, H., Doose, S., Sauer, M., Smith, J.C.: Hydrogen-Bond Driven Loop-Closure Kinetics in Unfolded Polypeptide Chains.PLOS COMPUTATIONAL BIOLOGY.6, (2010).
       
    • Goehler, A., Andre, S., Kaltner, H., Sauer, M., Gabius, H.-J., Doose, S.: Hydrodynamic Properties of Human Adhesion/Growth-Regulatory Galectins Studied by Fluorescence Correlation Spectroscopy.BIOPHYSICAL JOURNAL.98,3044-3053 (2010).
       
    • Kasper, R., Harke, B., Forthmann, C., Tinnefeld, P., Hell, S.W., Sauer, M.: Single-Molecule STED Microscopy with Photostable Organic Fluorophores.Small.6,1379--1384 (2010).
       
    • van de Linde, S., Wolter, S., Heilemann, M., Sauer, M.: The effect of photoswitching kinetics and labeling densities on super-resolution fluorescence imaging.JOURNAL OF BIOTECHNOLOGY.149,260-266 (2010).
       
    • Nottbohm, C.T., Sopher, R., Heilemann, M., Sauer, M., Goelzhaeuser, A.: Fluorescently labeled 1 nm thin nanomembranes.JOURNAL OF BIOTECHNOLOGY.149,267-271 (2010).
       
    • Schlereth, K., Beinoraviciute-Kellner, R., Zeitlinger, M.K., Bretz, A.C., Sauer, M., Charles, J.P., Vogiatzi, F., Leich, E., Samans, B., Eilers, M., Kisker, C., Rosenwald, A., Stiewe, T.: DNA Binding Cooperativity of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis.MOLECULAR CELL.38,356-368 (2010).
       
    • Wombacher, R., Heidbreder, M., van de Linde, S., Sheetz, M.P., Heilemann, M., Cornish, V.W., Sauer, M.: Live-cell super-resolution imaging with trimethoprim conjugates.NATURE METHODS.7,717-U72 (2010).
       
    • Endesfelder, U., van de Linde, S., Wolter, S., Sauer, M., Heilemann, M.: Subdiffraction-Resolution Fluorescence Microscopy of Myosin-Actin Motility.CHEMPHYSCHEM.11,836-840 (2010).
       
    • Seefeldt, B., Kasper, R., Beining, M., Mattay, J., Arden-Jacob, J., Kemnitzer, N., Drexhage, K.H., Heilemann, M., Sauer, M.: Spiropyrans as molecular optical switches.PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES.9,213-220 (2010).
       
    • Goelzhaeuser, A., Nattkemper, T., Niehaus, K., Puehler, A., Sauer, M.: BioImaging: Contributions from biology, physics and informatics.JOURNAL OF BIOTECHNOLOGY.149,227-228 (2010).
       

    2009[ nach oben ]

    • van de Linde, S., Endesfelder, U., Mukherjee, A., Schuettpelz, M., Wiebusch, G., Wolter, S., Heilemann, M., Sauer, M.: Multicolor photoswitching microscopy for subdiffraction-resolution fluorescence imaging.PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES.8,465-469 (2009).
       
    • Doose, S., Neuweiler, H., Sauer, M.: Fluorescence Quenching by Photoinduced Electron Transfer: A Reporter for Conformational Dynamics of Macromolecules.CHEMPHYSCHEM.10,1389-1398 (2009).
       
    • Heilemann, M., Dedecker, P., Hofkens, J., Sauer, M.: Photoswitches: Key molecules for subdiffraction-resolution fluorescence imaging and molecular quantification.LASER & PHOTONICS REVIEWS.3,180-202 (2009).
       
    • Heilemann, M., van de Linde, S., Mukherjee, A., Sauer, M.: Super-Resolution Imaging with Small Organic Fluorophores.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.48,6903-6908 (2009).
       
    • Hennig, S., van de Linde, S., Heilemann, M., Sauer, M.: Quantum Dot Triexciton Imaging with Three-Dimensional Subdiffraction Resolution.NANO LETTERS.9,2466-2470 (2009).
       

    2008[ nach oben ]

    • van de Linde, S., Kasper, R., Heilemann, M., Sauer, M.: Photoswitching microscopy with standard fluorophores.APPLIED PHYSICS B-LASERS AND OPTICS.93,725-731 (2008).
       
    • Seidel, T., Schnitzer, D., Golldack, D., Sauer, M., Dietz, K.-J.: Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis.BMC CELL BIOLOGY.9, (2008).
       
    • Schuettpelz, M., Schoening, J.C., Doose, S., Neuweiler, H., Peters, E., Staiger, D., Sauer, M.: Changes in conformational dynamics of mRNA upon AtGRP7 binding studied by fluorescence correlation spectroscopy.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.130,9507-9513 (2008).
       
    • Heilemann, M., van de Linde, S., Schuttpelz, M., Kasper, R., Seefeldt, B., Mukherjee, A., Tinnefeld, P., Sauer, M.: Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.47,6172-6176 (2008).
       
    • van de Linde, S., Sauer, M., Heilemann, M.: Subdiffraction-resolution fluorescence imaging of proteins in the mitochondrial inner membrane with photoswitchable fluorophores.JOURNAL OF STRUCTURAL BIOLOGY.164,250-254 (2008).
       
    • Vogelsang, J., Kasper, R., Steinhauer, C., Person, B., Heilemann, M., Sauer, M., Tinnefeld, P.: A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.47,5465-5469 (2008).
       
    • Seefeldt, B., Kasper, R., Seidel, T., Tinnefeld, P., Dietz, K.-J., Heilemann, M., Sauer, M.: Fluorescent proteins for single-molecule fluorescence applications.JOURNAL OF BIOPHOTONICS.1,74-82 (2008).
       

    2007[ nach oben ]

    • Schulze, P., Schuettpelz, M., Sauer, M., Belder, D.: Two-photon excited fluorescence detection at 420 nm for label-free detection of small aromatics and proteins in microchip electrophoresis.LAB ON A CHIP.7,1841-1844 (2007).
       
    • Agaylan, A., Binder, D., Sauer, M., Neuweiler, H., Meyer, O., Kiesewetter, H., Salama, A.: A highly sensitive particle agglutination assay for the detection of P53 autoantibodies in patients with lung cancer.Cancer.110,2502--2506 (2007).
       
    • Clifford, J.N., Bell, T.D.M., Tinnefeld, P., Heilemann, M., Melnikov, S.M., ichi Hotta, J., Sliwa, M., Dedecker, P., Sauer, M., Hofkens, J., Yeow, E.K.L.: Fluorescence of single molecules in polymer films: Sensitivity of blinking to local environment.JOURNAL OF PHYSICAL CHEMISTRY B.111,6987-6991 (2007).
       
    • Vogelsang, J., Doose, S., Sauer, M., Tinnefeld, P.: Single-Molecule Fluorescence Resonance Energy Transfer in Nanopipets: Improving Distance Resolution and Concentration Range.ANALYTICAL CHEMISTRY.79,7367-7375 (2007).
       
    • Doose, S., Barsch, H., Sauer, M.: Polymer properties of polythymine as revealed by translational diffusion.BIOPHYSICAL JOURNAL.93,1224-1234 (2007).
       
    • Doose, S., Neuweiler, H., Barsch, H., Sauer, M.: Probing polyproline structure and dynamics by photoinduced electron transfer provides evidence for deviations from a regular polyproline type II helix.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.104,17400-17405 (2007).
       
    • Neuweiler, H., Lollmann, M., Doose, S., Sauer, M.: Dynamics of unfolded polypeptide chains in crowded environment studied by fluorescence correlation spectroscopy.JOURNAL OF MOLECULAR BIOLOGY.365,856-869 (2007).
       

    2006[ nach oben ]

    • Sanchez-Mosteiro, G., van Dijk, E.M.H.P., Hernando, J., Heilemann, M., Tinnefeld, P., Sauer, M., Koberlin, F., Patting, M., Wahl, M., Erdmann, R., van Hulst, N.F., Garcia-Parajo, M.F.: DNA-based molecular wires: Multiple emission pathways of individual constructs.JOURNAL OF PHYSICAL CHEMISTRY B.110,26349-26353 (2006).
       
    • Schüttpelz, M., Müller, C., Neuweiler, H., Sauer, M.: UV Fluorescence Lifetime Imaging Microscopy: A Label-Free Method for Detection and Quantification of Protein Interactions.Analytical Chemistry.78,663-669 (2006).
       
    • Marmé, N., Friedrich, A., Müller, M., Nolte, O., Wolfrum, J., Hoheisel, J.D., Sauer, M., Knemeyer, J.-P.: Identification of single-point mutations in mycobacterial 16S rRNA sequences by confocal single-molecule fluorescence spectroscopy.Nucl. Acids Res.34,e90 (2006).
       
    • Kim, J., Doose, S., Neuweiler, H., Sauer, M.: The initial step of DNA hairpin folding: a kinetic analysis using fluorescence correlation spectroscopy.NUCLEIC ACIDS RESEARCH.34,2516-2527 (2006).
       
    • Kurtz, R., Fricke, M., Kalb, J., Tinnefeld, P., Sauer, M.: Application of multiline two-photon microscopy to functional in vivo imaging.JOURNAL OF NEUROSCIENCE METHODS.151,276-286 (2006).
       
    • Biebricher, A., Sauer, M., Tinnefeld, P.: Radiative and nonradiative rate fluctuations of single colloidal semiconductor nanocrystals.JOURNAL OF PHYSICAL CHEMISTRY B.110,5174-5178 (2006).
       
    • Heilemann, M., Kasper, R., Tinnefeld, P., Sauer, M.: Dissecting and reducing the heterogeneity of excited-state energy transport in DNA-Based photonic wires.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.128,16864-16875 (2006).
       
    • Cam, H., Griesmann, H., Beitzinger, M., Hofmann, L., Beinoraviciute-Kellner, R., Sauer, M., Huettinger-Kirchhof, N., Oswald, C., Friedl, P., Gattenloehner, S., Burek, C., Rosenwald, A., Stiewe, T.: p53 family members in myogenic differentiation and rhabdomyosarcoma development.CANCER CELL.10,281-293 (2006).
       

    2005[ nach oben ]

    • Heinlein, T., Biebricher, A., Schluter, P., Roth, C.M., Herten, D.P., Wolfrum, J., Heilemann, M., Muller, C., Tinnefeld, P., Sauer, M.: High-resolution colocalization of single molecules within the resolution gap of far-field microscopy.CHEMPHYSCHEM.6,949-955 (2005).
       
    • Neuweiler, H., Sauer, M.: Exploring life by single-molecule fluorescence spectroscopy.ANALYTICAL CHEMISTRY.77,178A-185A (2005).
       
    • Scheffler, S., Sauer, M., Neuweiler, H.: Monitoring antibody binding events in homogeneous solution by single-molecule fluorescence spectroscopy.ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS.219,665-678 (2005).
       
    • Patra, D., Gregor, I., Enderlein, J., Sauer, M.: Defocused imaging of quantum-dot angular distribution of radiation.APPLIED PHYSICS LETTERS.87, (2005).
       
    • Heilemann, M., Margeat, E., Kasper, R., Sauer, M., Tinnefeld, P.: Carbocyanine dyes as efficient reversible single-molecule optical switch.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY.127,3801-3806 (2005).
       
    • Neuweiler, H., Doose, S., Sauer, M.: A microscopic view of miniprotein folding: Enhanced folding efficiency through formation of an intermediate.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.102,16650-16655 (2005).
       
    • Stohr, K., Hafner, B., Nolte, O., Wolfrum, J., Sauer, M., Herten, D.P.: Species-specific identification of mycobacterial 16S rRNA PCR amplicons using smart probes.ANALYTICAL CHEMISTRY.77,7195-7203 (2005).
       
    • Tinnefeld, P., Sauer, M.: Branching Out of Single-Molecule Fluorescence Spectroscopy: Challenges for Chemistry and Influence on Biology.Angewandte Chemie International Edition.44,2642--2671 (2005).
       
    • Tinnefeld, P., Heilemann, M., Sauer, M.: Design of molecular photonic wires based on multistep electronic excitation transfer.CHEMPHYSCHEM.6,217-222 (2005).
       
    • Knemeyer, J.P., Marme, N., Hafner, B., Habl, G., Schafer, G., Muller, M., Nolte, O., Sauer, M., Wolfrum, J.: Self-quenching DNA probes based on dye dimerization for identification of mycobacteria.INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY.85,625-637 (2005).
       
    • Doose, S., Neuweiler, H., Sauer, M.: A close look at fluorescence quenching of organic dyes by tryptophan.CHEMPHYSCHEM.6,2277-2285 (2005).
       
    • Sauer, M.: Reversible molecular photoswitches: A key technology for nanoscience and fluorescence imaging.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.102,9433-9434 (2005).
       

    2004[ nach oben ]

    • Park, C.-W., Knemeyer, J.-P., Marmé, N., Möller, M., Spatz, J., Wolfrum, J., Sauer, M.: Accurate delivery of single biomolecules by polyethylene glycol coated submicrometer pipettes.Chemical Physics.301,105 - 110 (2004).
       
    • Neuweiler, H., Sauer, M.: Using photoinduced charge transfer reactions to study conformational dynamics of biopolymers at the single-molecule level.CURRENT PHARMACEUTICAL BIOTECHNOLOGY.5,285-298 (2004).
       
    • Masuo, S., Vosch, T., Cotlet, M., Tinnefeld, P., Habuchi, S., Bell, T.D.M., Oesterling, I., Beljonne, D., Champagne, B., Mullen, K., Sauer, M., Hofkens, J., Schryver, F.C.D.: Multichromophoric dendrimers as single-photon sources: A single-molecule study.JOURNAL OF PHYSICAL CHEMISTRY B.108,16686-16696 (2004).
       
    • Seebach, D., Namoto, K., Mahajan, Y.R., Bindschädler, P., Sustmann, R., Kirsch, M., Ryder, N.S., Weiss, M., Sauer, M., Roth, C., Werner, S., Beer, H.-D., Munding, C., Walde, P., Voser, M.: Chemical and Biological Investigations of beta-Oligoarginines.Chemistry & Biodiversity.1,65--97 (2004).
       
    • Biebricher, A., Paul, A., Tinnefeld, P., Golzhauser, A., Sauer, M.: Controlled three-dimensional immobilization of biomolecules on chemically patterned surfaces.JOURNAL OF BIOTECHNOLOGY.112,97-107 (2004).
       
    • Kluge, C., Seidel, T., Bolte, S., Sharma, S.S., Hanitzsch, M., Satiat-Jeunemaitre, B., Ross, J., Sauer, M., Golldack, D., Dietz, K.J.: Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex.BMC CELL BIOLOGY.5, (2004).