Prof. Dr. Markus Sauer

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+49 931 31-88687
m.sauer@uni-wuerzburg.de
Astrid Thal
+49 931 31-84507
+49 931 31-84509

Editorial boards
2015-presentHistochemistry and Cell Biology
2014-presentJournal of Structural Biology
2012-presentMethods in Applications in Fluorescence
2011-presentPLoS ONE

List of publications

2022[ to top ]
  • Glucose and Inositol Transporters, SLC5A1 and SLC5A3, in Glioblastoma Cell Migration. Brosch, Philippa K.; Korsa, Tessa; Taban, Danush; Eiring, Patrick; Hildebrand, Sascha; Neubauer, Julia; Zimmermann, Heiko; Sauer, Markus; Shirakashi, Ryo; Djuzenova, Cholpon S.; Sisario, Dmitri; Sukhorukov, Vladimir L. In Cancers, 14, S. 5794. 2022.
2021[ to top ]
  • A role for TASK2 channels in the human immunological synapse. Fernández-Orth, Juncal; Rolfes, Leoni; Gola, Lukas; Bittner, Stefan; Andronic, Joseph; Sukhorukov, Vladimir L.; Sisario, Dmitri; Landgraf, Peter; Dieterich, Daniela C.; Cerina, Manuela; Smalla, Karl-Heinz; Kähne, Thilo; Budde, Thomas; Kovac, Stjepana; Ruck, Tobias; Sauer, Markus; Meuth, Sven G. In European Journal of Immunology, 51(2), S. 342–353. John Wiley & Sons, Ltd, 2021.
  • Subdiffraction-resolution fluorescence imaging of immunological synapse formation between NK cells and A. fumigatus by expansion microscopy. Trinks, Nora; Reinhard, Sebastian; Drobny, Matthias; Heilig, Linda; Löffler, Jürgen; Sauer, Markus; Terpitz, Ulrich. In Communications Biology, 4(1), S. 1151-. 2021.
  • Superagonistic CD28 stimulation induces IFN-γ release from mouse T helper 1 cells in vitro and in vivo. Haack, Stephanie; Baiker, Sarah; Schlegel, Jan; Sauer, Markus; Sparwasser, Tim; Langenhorst, Daniela; Beyersdorf, Niklas. In European Journal of Immunology, 51(3), S. 738–741. John Wiley & Sons, Ltd, 2021.
  • Superresolution Microscopy of Sphingolipids. Schlegel, Jan; Sauer, Markus. In Lipid Rafts: Methods and Protocols, S. 303–311. Springer US, New York, NY, 2021.
  • Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria. Peters, Simon; Kaiser, Lena; Fink, Julian; Schumacher, Fabian; Perschin, Veronika; Schlegel, Jan; Sauer, Markus; Stigloher, Christian; Kleuser, Burkhard; Seibel, Jürgen; Schubert-Unkmeir, Alexandra. In Scientific Reports, 11(1), S. 4300-. 2021.
  • Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain. Beliu, Gerti; Altrichter, Steffen; Guixà-González, Ramon; Hemberger, Mareike; Brauer, Ina; Dahse, Anne-Kristin; Scholz, Nicole; Wieduwild, Robert; Kuhlemann, Alexander; Batebi, Hossein; Seufert, Florian; Pérez-Hernández, Guillermo; Hildebrand, Peter W.; Sauer, Markus; Langenhan, Tobias. In Molecular Cell, 81(5), S. 905–921.e5. 2021.
  • Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. Jansch, Charline; Ziegler, Georg C.; Forero, Andrea; Gredy, Sina; Wäldchen, Sina; Vitale, Maria Rosaria; Svirin, Evgeniy; Zöller, Johanna E. M.; Waider, Jonas; Günther, Katharina; Edenhofer, Frank; Sauer, Markus; Wischmeyer, Erhard; Lesch, Klaus-Peter. In Journal of Neural Transmission, 128(2), S. 225–241. 2021.
  • Chapter 15 - Ex-dSTORM and automated quantitative image analysis of expanded filamentous structures. Zwettler, Fabian U.; Reinhard, Sebastian; Sauer, Markus. In Expansion Microscopy for Cell Biology, Bd. 161, P. Guichard, V. Hamel (Hrsg.), S. 317–340. Academic Press, 2021.
  • Azidosphinganine enables metabolic labeling and detection of sphingolipid de novo synthesis. Fink, Julian; Schumacher, Fabian; Schlegel, Jan; Stenzel, Philipp; Wigger, Dominik; Sauer, Markus; Kleuser, Burkhard; Seibel, Jürgen. In Org. Biomol. Chem., 19(10), S. 2203–2212. The Royal Society of Chemistry, 2021.
  • Photoblueing of organic dyes can cause artifacts in super-resolution microscopy. Helmerich, Dominic A.; Beliu, Gerti; Matikonda, Siddharth S.; Schnermann, Martin J.; Sauer, Markus. In Nature Methods, 18(3), S. 253–257. 2021.
  • Acidosis-induced activation of anion channel SLAH3 in the flooding-related stress response of Arabidopsis. Lehmann, Julian; Jørgensen, Morten E.; Fratz, Stefanie; Müller, Heike M.; Kusch, Jana; Scherzer, Sönke; Navarro-Retamal, Carlos; Mayer, Dominik; Böhm, Jennifer; Konrad, Kai R.; Terpitz, Ulrich; Dreyer, Ingo; Mueller, Thomas D.; Sauer, Markus; Hedrich, Rainer; Geiger, Dietmar; Maierhofer, Tobias. In Current Biology. 2021.
  • Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab. García-Guerrero, Estefanía; Götz, Ralph; Doose, Sören; Sauer, Markus; Rodríguez-Gil, Alfonso; Nerreter, Thomas; Kortüm, K. Martin; Pérez-Simón, José A.; Einsele, Hermann; Hudecek, Michael; Danhof, Sophia. In Leukemia, 35(1), S. 201–214. 2021.
  • Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections. Pauli, Martin; Paul, Mila M.; Proppert, Sven; Mrestani, Achmed; Sharifi, Marzieh; Repp, Felix; Kürzinger, Lydia; Kollmannsberger, Philip; Sauer, Markus; Heckmann, Manfred; Sirén, Anna-Leena. In Communications Biology, 4(1), S. 407-. 2021.
2020[ to top ]
  • Chapter Ten - Conformationally restrained pentamethine cyanines and use in reductive single molecule localization microscopy. Matikonda, Siddharth S.; Götz, Ralph; McLaughlin, Ryan; Sauer, Markus; Schnermann, Martin J. In Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods, Bd. 641, D. M. Chenoweth (Hrsg.), S. 225–244. Academic Press, 2020.
  • Induction of BDNF Expression in Layer II/III and Layer V Neurons of the Motor Cortex Is Essential for Motor Learning. Andreska, Thomas; Rauskolb, Stefanie; Schukraft, Nina; Lüningschrör, Patrick; Sasi, Manju; Signoret-Genest, Jeremy; Behringer, Marcus; Blum, Robert; Sauer, Markus; Tovote, Philip; Sendtner, Michael. In J. Neurosci., 40(33), S. 6289-. 2020.
  • Multiple-Labeled Antibodies Behave Like Single Emitters in Photoswitching Buffer. Helmerich, Dominic A.; Beliu, Gerti; Sauer, Markus. In ACS Nano. American Chemical Society, 2020.
  • Molecular resolution imaging by post-labeling expansion single-molecule localization microscopy (Ex-SMLM). Zwettler, Fabian U.; Reinhard, Sebastian; Gambarotto, Davide; Bell, Toby D. M.; Hamel, Virginie; Guichard, Paul; Sauer, Markus. In Nature Communications, 11(1), S. 3388-. 2020.
  • BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation. Volz, Julia; Kusch, Charly; Beck, Sarah; Popp, Michael; Vögtle, Timo; Meub, Mara; Scheller, Inga; Heil, Hannah S.; Preu, Julia; Schuhmann, Michael K.; Hemmen, Katherina; Premsler, Thomas; Sickmann, Albert; Heinze, Katrin G.; Stegner, David; Stoll, Guido; Braun, Attila; Sauer, Markus; Nieswandt, Bernhard. In The Journal of Clinical Investigation, 130(11), S. 6064–6079. The American Society for Clinical Investigation, 2020.
  • Nanoscale imaging of bacterial infections by sphingolipid expansion microscopy. Götz, Ralph; Kunz, Tobias C.; Fink, Julian; Solger, Franziska; Schlegel, Jan; Seibel, Jürgen; Kozjak-Pavlovic, Vera; Rudel, Thomas; Sauer, Markus. In Nature Communications, 11(1), S. 6173-. 2020.
  • Variant signaling topology at the cancer cell–T-cell interface induced by a two-component T-cell engager. Kouhestani, Dina; Geis, Maria; Alsouri, Saed; Bumm, Thomas G. P.; Einsele, Hermann; Sauer, Markus; Stuhler, Gernot. In Cellular & Molecular Immunology. 2020.
  • A Trojan Horse for live-cell super-resolution microscopy. Beliu, Gerti; Sauer, Markus. In Light: Science & Applications, 9(1), S. 2-. 2020.
  • Super-resolution imaging reveals the nanoscale organization of metabotropic glutamate receptors at presynaptic active zones. Siddig, Sana; Aufmkolk, Sarah; Doose, Sören; Jobin, Marie-Lise; Werner, Christian; Sauer, Markus; Calebiro, Davide. In Sci Adv, 6(16), S. eaay7193-. 2020.
  • Reconstituting NK Cells After Allogeneic Stem Cell Transplantation Show Impaired Response to the Fungal Pathogen Aspergillus fumigatus. Weiss, Esther; Schlegel, Jan; Terpitz, Ulrich; Weber, Michael; Linde, Jörg; Schmitt, Anna-Lena; Hünniger, Kerstin; Marischen, Lothar; Gamon, Florian; Bauer, Joachim; Löffler, Claudia; Kurzai, Oliver; Morton, Charles Oliver; Sauer, Markus; Einsele, Hermann; Loeffler, Juergen. In Frontiers in Immunology, 11. 2020.
  • Using Expansion Microscopy to Visualize and Characterize the Morphology of Mitochondrial Cristae. Kunz, Tobias C.; Götz, Ralph; Gao, Shiqiang; Sauer, Markus; Kozjak-Pavlovic, Vera. In Frontiers in Cell and Developmental Biology, 8, S. 617-. 2020.
  • Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy. Zwettler, Fabian U.; Spindler, Marie-Christin; Reinhard, Sebastian; Klein, Teresa; Kurz, Andreas; Benavente, Ricardo; Sauer, Markus. In Nature Communications, 11(1), S. 3222-. 2020.
  • ‘Live and Large’: Super-Resolution Optical Fluctuation Imaging (SOFI) and Expansion Microscopy (ExM) of Microtubule Remodelling by Rabies Virus P Protein. Rozario, Ashley M.; Zwettler, Fabian; Duwé, Sam; Hargreaves, Riley B.; Brice, Aaron; Dedecker, Peter; Sauer, Markus; Moseley, Gregory W.; Whelan, Donna R.; Bell, Toby D. M. In Aust. J. Chem. 2020.
  • Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy. Thiele, Jan Christoph; Helmerich, Dominic A.; Oleksiievets, Nazar; Tsukanov, Roman; Butkevich, Eugenia; Sauer, Markus; Nevskyi, Oleksii; Enderlein, Jörg. In ACS Nano, 14(10), S. 14190–14200. American Chemical Society, 2020.
  • FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy. Memmel, Simon; Sisario, Dmitri; Zimmermann, Heiko; Sauer, Markus; Sukhorukov, Vladimir L.; Djuzenova, Cholpon S.; Flentje, Michael. In BMC Bioinformatics, 21(1), S. 27-. 2020.
  • Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Forero, Andrea; Ku, Hsing-Ping; Malpartida, Ana Belén; Wäldchen, Sina; Alhama-Riba, Judit; Kulka, Christina; Aboagye, Benjamin; Norton, William H.J; Young, Andrew M.J; Ding, Yu-Qiang; Blum, Robert; Sauer, Markus; Rivero, Olga; Lesch, Klaus-Peter. In Neuropharmacology, 168, S. 108018-. 2020.
  • Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM. Wäldchen, Felix; Schlegel, Jan; Götz, Ralph; Luciano, Michael; Schnermann, Martin; Doose, Sören; Sauer, Markus. In Nature Communications, 11(1), S. 887-. 2020.
  • Expansion Microscopy for Cell Biology Analysis in Fungi. Götz, Ralph; Panzer, Sabine; Trinks, Nora; Eilts, Janna; Wagener, Johannes; Turrà, David; Di Pietro, Antonio; Sauer, Markus; Terpitz, Ulrich. In Frontiers in Microbiology, 11. 2020.
2019[ to top ]
  • Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium. Derakhshani, Shaghayegh; Kurz, Andreas; Japtok, Lukasz; Schumacher, Fabian; Pilgram, Lisa; Steinke, Maria; Kleuser, Burkhard; Sauer, Markus; Schneider-Schaulies, Sibylle; Avota, Elita. In Frontiers in Immunology, 10, S. 1294-. 2019.
  • Imaging cellular ultrastructures using expansion microscopy (U-ExM). Gambarotto, Davide; Zwettler, Fabian U.; Le Guennec, Maeva; Schmidt-Cernohorska, Marketa; Fortun, Denis; Borgers, Susanne; Heine, Jörn; Schloetel, Jan-Gero; Reuss, Matthias; Unser, Michael; Boyden, Edward S.; Sauer, Markus; Hamel, Virginie; Guichard, Paul. In Nature Methods, 16(1), S. 71–74. 2019.
  • Detection of Chlamydia Developmental Forms and Secreted Effectors by Expansion Microscopy. Kunz, Tobias C.; Götz, Ralph; Sauer, Markus; Rudel, Thomas. In Frontiers in Cellular and Infection Microbiology, 9, S. 276-. 2019.
  • Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites. Schlegel, Jan; Peters, Simon; Doose, Sören; Schubert-Unkmeir, Alexandra; Sauer, Markus. In Frontiers in Cell and Developmental Biology, 7, S. 194-. 2019.
  • Bioorthogonal labeling with tetrazine-dyes for super-resolution microscopy. Beliu, Gerti; Kurz, Andreas J.; Kuhlemann, Alexander C.; Behringer-Pliess, Lisa; Meub, Mara; Wolf, Natalia; Seibel, Jürgen; Shi, Zhen-Dan; Schnermann, Martin; Grimm, Jonathan B.; Lavis, Luke D.; Doose, Sören; Sauer, Markus. In Communications Biology, 2(1), S. 261-. 2019.
  • Neisseria meningitidis Type IV Pili Trigger Ca2+-Dependent Lysosomal Trafficking of the Acid Sphingomyelinase To Enhance Surface Ceramide Levels. Peters, Simon; Schlegel, Jan; Becam, Jérôme; Avota, Elita; Sauer, Markus; Schubert-Unkmeir, Alexandra. In Infect. Immun., 87(8), A. J. Bäumler (Hrsg.), S. e00410–19. 2019.
  • Registration and Visualization of Correlative Super-Resolution Microscopy Data. Reinhard, Sebastian; Aufmkolk, Sarah; Sauer, Markus; Doose, Sören. In Biophysical Journal, 116(11), S. 2073–2078. 2019.
  • FSP1 is a glutathione-independent ferroptosis suppressor. Doll, Sebastian; Freitas, Florencio Porto; Shah, Ron; Aldrovandi, Maceler; da Silva, Milene Costa; Ingold, Irina; Grocin, Andrea Goya; Xavier da Silva, Thamara Nishida; Panzilius, Elena; Scheel, Christina H.; Mourão, André; Buday, Katalin; Sato, Mami; Wanninger, Jonas; Vignane, Thibaut; Mohana, Vaishnavi; Rehberg, Markus; Flatley, Andrew; Schepers, Aloys; Kurz, Andreas; White, Daniel; Sauer, Markus; Sattler, Michael; Tate, Edward William; Schmitz, Werner; Schulze, Almut; O’Donnell, Valerie; Proneth, Bettina; Popowicz, Grzegorz M.; Pratt, Derek A.; Angeli, José Pedro Friedmann; Conrad, Marcus. In Nature, 575(7784), S. 693–698. 2019.
  • Platelet lamellipodium formation is not required for thrombus formation and stability. Schurr, Yvonne; Sperr, Andreas; Volz, Julia; Beck, Sarah; Reil, Lucy; Kusch, Charly; Eiring, Patrick; Bryson, Sheila; Sauer, Markus; Nieswandt, Bernhard; Machesky, Laura; Bender, Markus. In Blood, 134, S. 2318–2329. 2019.
  • Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nerreter, Thomas; Letschert, Sebastian; Götz, Ralph; Doose, Sören; Danhof, Sophia; Einsele, Hermann; Sauer, Markus; Hudecek, Michael. In Nature Communications, 10(1), S. 3137-. 2019.
  • Super-resolution microscopy demystified. Schermelleh, Lothar; Ferrand, Alexia; Huser, Thomas; Eggeling, Christian; Sauer, Markus; Biehlmaier, Oliver; Drummen, Gregor P. C. In Nature Cell Biology, 21(1), S. 72–84. 2019.
  • Generation of site-distinct N-glycan variants for in vitro bioactivity testing. Brühlmann, David; Vuillemin, Thomas; Satwekar, Abhijeet; Galano, Eugenio; Palmese, Angelo; D’Angelo, Alessandra; Manco, Zeynep; Souquet, Jonathan; Broly, Hervé; Sauer, Markus; Hemberger, Jürgen; Jordan, Martin. In Biotechnology and Bioengineering, 116(5), S. 1017–1028. John Wiley & Sons, Ltd, 2019.
  • Nanogels Enable Efficient miRNA Delivery and Target Gene Downregulation in Transfection-Resistant Multiple Myeloma Cells. Zilkowski, Ilona; Ziouti, Fani; Schulze, Andres; Hauck, Stefanie; Schmidt, Stefanie; Mainz, Laura; Sauer, Markus; Albrecht, Krystyna; Jundt, Franziska; Groll, Jürgen. In Biomacromolecules, 20(2), S. 916–926. American Chemical Society, 2019.
2018[ to top ]
  • Nanostructure of DNA repair foci revealed by superresolution microscopy. Sisario, Dmitri; Memmel, Simon; Doose, Sören; Neubauer, Julia; Zimmermann, Heiko; Flentje, Michael; Djuzenova, Cholpon S.; Sauer, Markus; Sukhorukov, Vladimir L. In The FASEB Journal, S. fj.201701435-. Federation of American Societies for Experimental Biology, 2018.
  • The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling. Börtlein, Charlene; Draeger, Annette; Schoenauer, Roman; Kuhlemann, Alexander; Sauer, Markus; Schneider-Schaulies, Sibylle; Avota, Elita. In Frontiers in Immunology, 9, S. 815-. 2018.
  • Bioorthogonal Click Chemistry Enables Site-specific Fluorescence Labeling of Functional NMDA Receptors for Super-Resolution Imaging. Neubert, Franziska; Beliu, Gerti; Terpitz, Ulrich; Werner, Christian; Geis, Christian; Sauer, Markus; Doose, Sören. In Angewandte Chemie International Edition, 57(50), S. 16364–16369. John Wiley & Sons, Ltd, 2018.
  • Sharpening emitter localization in front of a tuned mirror. Heil, Hannah S.; Schreiber, Benjamin; Götz, Ralph; Emmerling, Monika; Dabauvalle, Marie-Christine; Krohne, Georg; Höfling, Sven; Kamp, Martin; Sauer, Markus; Heinze, Katrin G. In Light: Science & Applications, 7(1), S. 99-. 2018.
2017[ to top ]
  • Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Forero, Andrea; Rivero, Olga; Wäldchen, Sina; Ku, Hsing-Ping; Kiser, Dominik P.; Gärtner, Yvonne; Pennington, Laura S.; Waider, Jonas; Gaspar, Patricia; Jansch, Charline; Edenhofer, Frank; Resink, Thérèse J.; Blum, Robert; Sauer, Markus; Lesch, Klaus-Peter. In Frontiers in Cellular Neuroscience, 11, S. 307-. 2017.
  • Chapter 2 - 3D subcellular localization with superresolution array tomography on ultrathin sections of various species. Markert, Sebastian M.; Bauer, Vivien; Muenz, Thomas S.; Jones, Nicola G.; Helmprobst, Frederik; Britz, Sebastian; Sauer, Markus; Rössler, Wolfgang; Engstler, Markus; Stigloher, Christian. In Correlative Light and Electron Microscopy III, Bd. 140, T. Müller-Reichert, P. Verkade (Hrsg.), S. 21–47. Academic Press, 2017.
  • Characterization of Plasma Membrane Ceramides by Super-Resolution Microscopy. Burgert, Anne; Schlegel, Jan; Bécam, Jérôme; Doose, Sören; Bieberich, Erhard; Schubert-Unkmeir, Alexandra; Sauer, Markus. In Angewandte Chemie. 2017.
  • Migration pattern, actin cytoskeleton organization and response to PI3K-, mTOR-, and Hsp90-inhibition of glioblastoma cells with different invasive capacities. Memmel, Simon; Sisario, Dmitri; Zöller, Caren; Fiedler, Vanessa; Katzer, Astrid; Heiden, Robin; Becker, Nicholas; Eing, Lorenz; Ferreira, Fábio L.R.; Zimmermann, Heiko; Sauer, Markus; Flentje, Michael; Sukhorukov, Vladimir L.; Djuzenova, Cholpon S. In Oncotarget, 8, S. 45298–45310. 2017.
  • Incorporation studies of clickable ceramides in Jurkat cell plasma membranes. Walter, T.; Schlegel, J.; Burgert, A.; Kurz, A.; Seibel, J.; Sauer, M. In Chem. Commun., 53(51), S. 6836–6839. The Royal Society of Chemistry, 2017.
  • Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality. Brühlmann, David; Sokolov, Michael; Butté, Alessandro; Sauer, Markus; Hemberger, Jürgen; Souquet, Jonathan; Broly, Hervé; Jordan, Martin. In Biotechnology and Bioengineering, 114(7), S. 1448–1458. 2017.
  • Single-Molecule Localization Microscopy in Eukaryotes. Sauer, Markus; Heilemann, Mike. In Chem. Rev. American Chemical Society, 2017.
  • Cyanine Conformational Restraint in the Far-Red Range. Michie, Megan S.; Götz, Ralph; Franke, Christian; Bowler, Matthew; Kumari, Nikita; Magidson, Valentin; Levitus, Marcia; Loncarek, Jadranka; Sauer, Markus; Schnermann, Martin J. In J. Am. Chem. Soc., 139(36), S. 12406–12409. American Chemical Society, 2017.
  • Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission. Maric, Hans Michael; Hausrat, Torben Johann; Neubert, Franziska; Dalby, Nils Ole; Doose, Sören; Sauer, Markus; Kneussel, Matthias; Strømgaard, Kristian. In Nature Chemical Biology, 13, S. 153-. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved., 2017.
  • Cell culture media supplemented with raffinose reproducibly enhances high mannose glycan formation. Brühlmann, David; Muhr, Anais; Parker, Rebecca; Vuillemin, Thomas; Bucsella, Blanka; Kalman, Franka; Torre, Serena; La Neve, Fabio; Lembo, Antonio; Haas, Tobias; Sauer, Markus; Souquet, Jonathan; Broly, Hervé; Hemberger, Jürgen; Jordan, Martin. In Journal of Biotechnology, 252(Supplement C), S. 32–42. 2017.
  • Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. Scholz, Nicole; Guan, Chonglin; Nieberler, Matthias; Grotemeyer, Alexander; Maiellaro, Isabella; Gao, Shiqiang; Beck, Sebastian; Pawlak, Matthias; Sauer, Markus; Asan, Esther; Rothemund, Sven; Winkler, Jana; Prömel, Simone; Nagel, Georg; Langenhan, Tobias; Kittel, Robert J. In eLife, 6, H. J. Bellen (Hrsg.), S. e28360-. eLife Sciences Publications, Ltd, 2017.
  • CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells. Ziegler, Sabrina; Weiss, Esther; Schmitt, Anna-Lena; Schlegel, Jan; Burgert, Anne; Terpitz, Ulrich; Sauer, Markus; Moretta, Lorenzo; Sivori, Simona; Leonhardt, Ines; Kurzai, Oliver; Einsele, Hermann; Loeffler, Juergen. In Scientific Reports, 7(1), S. 6138-. 2017.
  • CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells. Ziegler, Sabrina; Weiss, Esther; Schmitt, Anna-Lena; Schlegel, Jan; Burgert, Anne; Terpitz, Ulrich; Sauer, Markus; Moretta, Lorenzo; Sivori, Simona; Leonhardt, Ines; Kurzai, Oliver; Einsele, Hermann; Loeffler, Juergen. In Scientific Reports, 7(1), S. 6138-. 2017.
  • Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. Scholz, Nicole; Guan, Chonglin; Nieberler, Matthias; Grotemeyer, Alexander; Maiellaro, Isabella; Gao, Shiqiang; Beck, Sebastian; Pawlak, Matthias; Sauer, Markus; Asan, Esther; Rothemund, Sven; Winkler, Jana; Prömel, Simone; Nagel, Georg; Langenhan, Tobias; Kittel, Robert J. In eLife, 6, H. J. Bellen (Hrsg.), S. e28360-. eLife Sciences Publications, Ltd, 2017.
  • Quantifying protein densities on cell membranes using super-resolution optical fluctuation imaging. Lukeš, Tomáš; Glatzová, Daniela; Kvíčalová, Zuzana; Levet, Florian; Benda, Aleš; Letschert, Sebastian; Sauer, Markus; Brdička, Tomáš; Lasser, Theo; Cebecauer, Marek. In Nature Communications, 8(1), S. 1731-. 2017.
2016[ to top ]
  • Super-resolution imaging of plasma membrane proteins with click chemistry. Mateos-Gil, Pablo; Letschert, Sebastian; Doose, Soeren; Sauer, Markus. In Frontiers in Cell and Developmental Biology, 4, S. 98-. 2016.
  • Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Yadav, Preeti; Selvaraj, Bhuvaneish T.; Bender, Florian L. P.; Behringer, Marcus; Moradi, Mehri; Sivadasan, Rajeeve; Dombert, Benjamin; Blum, Robert; Asan, Esther; Sauer, Markus; Julien, Jean-Pierre; Sendtner, Michael. In Acta Neuropathologica, 132(1), S. 93–110. 2016.
  • Photometry unlocks 3D information from 2D localization microscopy data. Franke, Christian; Sauer, Markus; van de Linde, Sebastian. In Nat Meth, advance online publication. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved., 2016.
  • The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni. Dugar, Gaurav; Svensson, Sarah L.; Bischler, Thorsten; Wäldchen, Sina; Reinhardt, Richard; Sauer, Markus; Sharma, Cynthia M. In Nature Communications, 7, S. 11667-. The Author(s), 2016.
  • OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Jung, L A; Gebhardt, A; Koelmel, W; Ade, C P; Walz, S; Kuper, J; von Eyss, B; Letschert, S; Redel, C; d’Artista, L; Biankin, A; Zender, L; Sauer, M; Wolf, E; Evan, G; Kisker, C; Eilers, M. In Oncogene, 36, S. 1911-. Macmillan Publishers Limited, part of Springer Nature., 2016.
  • Filling the gap: adding super-resolution to array tomography for correlated ultrastructural and molecular identification of electrical synapses at the C. elegans connectome. Markert, Sebastian Matthias; Britz, Sebastian; Proppert, Sven; Lang, Marietta; Witvliet, Daniel; Mulcahy, Ben; Sauer, Markus; Zhen, Mei; Bessereau, Jean-Louis; Stigloher, Christian. In Neurophotonics, 3(4), S. 041802–041802. 2016.
  • Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition. Werner, Christian; Pauli, Martin; Doose, Sören; Weishaupt, Andreas; Haselmann, Holger; Grünewald, Benedikt; Sauer, Markus; Heckmann, Manfred; Toyka, Klaus V.; Asan, Esther; Sommer, Claudia; Geis, Christian. In Brain, 139(2), S. 365–379. 2016.
  • Synthesis and application of water-soluble, photoswitchable cyanine dyes for bioorthogonal labeling of cell-surface carbohydrates. Alexander, Mertsch; Sebastian, Letschert; Elisabeth, Memmel; Markus, Sauer; Jürgen, Seibel. S. 347-. 2016.
  • A Functionalized Sphingolipid Analogue for Studying Redistribution during Activation in Living T Cells. Collenburg, Lena; Walter, Tim; Burgert, Anne; Müller, Nora; Seibel, Jürgen; Japtok, Lukasz; Kleuser, Burkhard; Sauer, Markus; Schneider-Schaulies, Sibylle. In The Journal of Immunology, 196(9), S. 3951–3962. 2016.
2015[ to top ]
  • Instant Live-Cell Super-Resolution Imaging of Cellular Structures by Nanoinjection of Fluorescent Probes. Hennig, Simon; van de Linde, Sebastian; Lummer, Martina; Simonis, Matthias; Huser, Thomas; Sauer, Markus. In Nano Lett., 15(2), S. 1374–1381. American Chemical Society, 2015.
  • Quantitative Super-Resolution Microscopy of Nanopipette-Deposited Fluorescent Patterns. Hennig, Simon; van de Linde, Sebastian; Bergmann, Stephan; Huser, Thomas; Sauer, Markus. In ACS Nano, 9(8), S. 8122–8130. American Chemical Society, 2015.
  • Quantifying molecular colocalization in live cell fluorescence microscopy. Humpert, Fabian; Yahiatène, Idir; Lummer, Martina; Sauer, Markus; Huser, Thomas. In Journal of Biophotonics, 8(1-2), S. 124–132. WILEY-VCH Verlag, 2015.
  • Hypotonic Activation of the Myo-Inositol Transporter SLC5A3 in HEK293 Cells Probed by Cell Volumetry, Confocal and Super-Resolution Microscopy. Andronic, Joseph; Shirakashi, Ryo; Pickel, Simone U.; Westerling, Katherine M.; Klein, Teresa; Holm, Thorge; Sauer, Markus; Sukhorukov, Vladimir L. In PLoS ONE, 10(3), S. e0119990. Public Library of Science, 2015.
  • Elucidation of synaptonemal complex organization by super-resolution imaging with isotropic resolution. Schücker, Katharina; Holm, Thorge; Franke, Christian; Sauer, Markus; Benavente, Ricardo. In Proceedings of the National Academy of Sciences, 112(7), S. 2029–2033. 2015.
  • Super-resolution microscopy of the synaptic active zone. Ehmann, Nadine; Sauer, Markus; Kittel, Robert J. In Frontiers in Cellular Neuroscience, 9(7). 2015.
  • Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation. Paul, Mila M; Pauli, Martin; Ehmann, Nadine; Hallermann, Stefan; Sauer, Markus; Kittel, Robert J; Heckmann, Manfred. In Frontiers in Cellular Neuroscience, 9(29). 2015.
  • Synthesis of a Far-Red Photoactivatable Silicon-Containing Rhodamine for Super-Resolution Microscopy. Grimm, Jonathan B.; Klein, Teresa; Kopek, Benjamin G.; Shtengel, Gleb; Hess, Harald F.; Sauer, Markus; Lavis, Luke D. In Angewandte Chemie, S. n/a-n/a. WILEY-VCH Verlag, 2015.
  • Light-induced cell damage in live-cell super-resolution microscopy. Wäldchen, Sina; Lehmann, Julian; Klein, Teresa; van de Linde, Sebastian; Sauer, Markus. In Scientific Reports, 5, S. 15348-. Nature Publishing Group, 2015.
  • Tailoring recombinant protein quality by rational media design. Brühlmann, David; Jordan, Martin; Hemberger, Jürgen; Sauer, Markus; Stettler, Matthieu; Broly, Hervé. In Biotechnology Progress, 31(3), S. 615–629. 2015.
  • Artifacts in single-molecule localization microscopy. Burgert, Anne; Letschert, Sebastian; Doose, Sören; Sauer, Markus. In Histochemistry and Cell Biology, 144, S. 123–131. 2015.
  • Spatio-temporal Remodeling of Functional Membrane Microdomains Organizes the Signaling Networks of a Bacterium. Schneider, Johannes; Klein, Teresa; Mielich-Süss, Benjamin; Koch, Gudrun; Franke, Christian; Kuipers, Oscar P.; Kovács, Ákos T.; Sauer, Markus; Lopez, Daniel. In PLoS Genet, 11(4), S. e1005140-. Public Library of Science, 2015.
2014[ to top ]
  • Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states. Ehmann, Nadine; van de Linde, Sebastian; Alon, Amit; Ljaschenko, Dmitrij; Keung, Xi Zhen; Holm, Thorge; Rings, Annika; DiAntonio, Aaron; Hallermann, Stefan; Ashery, Uri; Heckmann, Manfred; Sauer, Markus; Kittel, Robert J. In Nat Commun, 5. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved., 2014.
  • Eight years of single-molecule localization microscopy. Klein, Teresa; Proppert, Sven; Sauer, Markus. In Histochemistry and Cell Biology, 141(6), S. 561–575. 2014.
  • Timing Protein Assembly in Neurons. Sauer, Markus. In Chemistry & Biology, 21(6), S. 703–704. 2014.
  • Correlative super-resolution fluorescence and electron microscopy of the nuclear pore complex with molecular resolution. Löschberger, Anna; Franke, Christian; Krohne, Georg; van de Linde, Sebastian; Sauer, Markus. In Journal of Cell Science, 127(20), S. 4351–4355. 2014.
  • Super-Resolution Imaging of Plasma Membrane Glycans. Letschert, Sebastian; Göhler, Antonia; Franke, Christian; Bertleff-Zieschang, Nadja; Memmel, Elisabeth; Doose, Sören; Seibel, Jürgen; Sauer, Markus. In Angewandte Chemie International Edition, S. n/a-n/a. WILEY-VCH Verlag, 2014.
  • Differential Interaction of Tomosyn with Syntaxin and SNAP25 Depends on Domains in the WD40 β-Propeller Core and Determines Its Inhibitory Activity. Bielopolski, Noa; Lam, Alice D.; Bar-On, Dana; Sauer, Markus; Stuenkel, Edward L.; Ashery, Uri. In Journal of Biological Chemistry, 289, S. 17087–17099. 2014.
  • A Blueprint for Cost-Efficient Localization Microscopy. Holm, Thorge; Klein, Teresa; Löschberger, Anna; Klamp, Tobias; Wiebusch, Gerd; van de Linde, Sebastian; Sauer, Markus. In ChemPhysChem, 15(4), S. 651–654. WILEY-VCH Verlag, 2014.
  • How to switch a fluorophore: from undesired blinking to controlled photoswitching. van de Linde, Sebastian; Sauer, Markus. In Chem. Soc. Rev. 2014, 43(4), S. 1076–1087. The Royal Society of Chemistry, 2014.
  • Focus on Super-Resolution Imaging with Direct Stochastic Optical Reconstruction Microscopy (dSTORM). Whelan, Donna R.; Holm, Thorge; Sauer, Markus; Bell, Toby D. M. In Australian Journal of Chemistry, 67, S. 179–183. 2014.
  • PET-FCS: Probing Rapid Structural Fluctuations of Proteins and Nucleic Acids by Single-Molecule Fluorescence Quenching. Sauer, Markus; Neuweiler, Hannes. In Methods Mol Biol - Fluorescence Spectroscopy and Microscopy, Bd. 1076, Y. Engelborghs, A. J. Visser (Hrsg.), S. 597–615. Humana Press, 2014.
  • Click chemistry for the conservation of cellular structures and fluorescent proteins: ClickOx. Löschberger, Anna; Niehörster, Thomas; Sauer, Markus. In Biotechnology Journal, S. n/a-n/a. WILEY-VCH Verlag, 2014.
  • High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons. Andreska, Thomas; Aufmkolk, Sarah; Sauer, Markus; Blum, Robert. In Frontiers in Cellular Neuroscience, 8(107). 2014.
  • Cubic B-spline calibration for 3D super-resolution measurements using astigmatic imaging. Proppert, Sven; Wolter, Steve; Holm, Thorge; Klein, Teresa; van de Linde, Sebastian; Sauer, Markus. In Opt. Express, 22(9), S. 10304–10316. OSA, 2014.
  • The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress. Mehlitz, Adrian; Karunakaran, Karthika; Herweg, Jo-Ana; Krohne, Georg; van de Linde, Sebastian; Rieck, Elke; Sauer, Markus; Rudel, Thomas. In Cellular Microbiology, S. n/a-n/a. 2014.
2013[ to top ]
  • Investigating Cellular Structures at the Nanoscale with Organic Fluorophores. van de Linde, Sebastian; Aufmkolk, Sarah; Franke, Christian; Holm, Thorge; Klein, Teresa; Löschberger, Anna; Proppert, Sven; Wolter, Steve; Sauer, Markus. In Chemistry & Biology, 20(1), S. 8–18. 2013.
  • Permeation through Phospholipid Bilayers, Skin-Cell Penetration, Plasma Stability, and CD Spectra of α- and β-Oligoproline Derivatives. Kolesinska, Beata; Podwysocka, Dominika J.; Rueping, Magnus A.; Seebach, Dieter; Kamena, Faustin; Walde, Peter; Sauer, Markus; Windschiegl, Barbara; Meyer-Ács, Mira; Vor der Brüggen, Marc; Giehring, Sebastian. In Chemistry & Biodiversity, 10(1), S. 1–38. WILEY-VCH Verlag, 2013.
  • Localization microscopy coming of age: from concepts to biological impact. Sauer, Markus. In Journal of Cell Science, 126(16), S. 3505–3513. 2013.
  • Investigating Cellular Structures at the Nanoscale with Organic Fluorophores. van de Linde, Sebastian; Aufmkolk, Sarah; Franke, Christian; Holm, Thorge; Klein, Teresa; Löschberger, Anna; Proppert, Sven; Wolter, Steve; Sauer, Markus. In Chemistry & Biology, 20(1), S. 8–18. 2013.
  • Methylene blue- and thiol-based oxygen depletion for super-resolution imaging. Schäfer, Philip; van de Linde, Sebastian; Lehmann, Julian; Sauer, Markus; Doose, Sören. In Analytical Chemistry, 85(6), S. 3393–3400. 2013.
  • Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes. Andronic, Joseph; Bobak, Nicole; Bittner, Stefan; Ehling, Petra; Kleinschnitz, Christoph; Herrmann, Alexander M.; Zimmermann, Heiko; Sauer, Markus; Wiendl, Heinz; Budde, Thomas; Meuth, Sven G.; Sukhorukov, Vladimir L. In Biochimica et Biophysica Acta (BBA) - Biomembranes, 1828(2), S. 699–707. 2013.
  • Investigating infection processes with a workflow from organic chemistry to biophysics: the combination of metabolic glycoengineering, super-resolution fluorescence imaging and proteomics. Seibel, Jürgen; König, Simone; Göhler, Antonia; Doose, Sören; Memmel, Elisabeth; Bertleff, Nadja; Sauer, Markus. In Expert Rev Proteomics, 10(1), S. 25–31. Expert Reviews, 2013.
  • Localization microscopy coming of age: from concepts to biological impact. Sauer, Markus. In Journal of Cell Science, 126(16), S. 3505–3513. 2013.
  • Permeation through Phospholipid Bilayers, Skin-Cell Penetration, Plasma Stability, and CD Spectra of α- and β-Oligoproline Derivatives. Kolesinska, Beata; Podwysocka, Dominika J.; Rueping, Magnus A.; Seebach, Dieter; Kamena, Faustin; Walde, Peter; Sauer, Markus; Windschiegl, Barbara; Meyer-Ács, Mira; Vor der Brüggen, Marc; Giehring, Sebastian. In Chemistry & Biodiversity, 10(1), S. 1–38. WILEY-VCH Verlag, 2013.
  • Highly Rapid Amplification-Free and Quantitative DNA Imaging Assay. Klamp, Tobias; Camps, Marta; Nieto, Benjamin; Guasch, Francesc; Ranasinghe, Rohan T.; Wiedemann, Jens; Petrášek, Zdeněk; Schwille, Petra; Klenerman, David; Sauer, Markus. In Sci. Rep., 3. Macmillan Publishers Limited. All rights reserved, 2013.
  • A New Set of Reversibly Photoswitchable Fluorescent Proteins for Use in Transgenic Plants. Lummer, Martina; Humpert, Fabian; Wiedenlübbert, Matthias; Sauer, Markus; Schüttpelz, Mark; Staiger, Dorothee. In Molecular Plant, 6(5), S. 1518–1530. 2013.
  • Elements of Transcriptional Machinery Are Compatible among Plants and Mammals. Wolf, Annette; Akrap, Nina; Marg, Berenice; Galliardt, Helena; Heiligentag, Martyna; Humpert, Fabian; Sauer, Markus; Kaltschmidt, Barbara; Kaltschmidt, Christian; Seidel, Thorsten. In PLOS ONE, 8(1), S. e53737-. Public Library of Science, 2013.
2012[ to top ]
  • Correlation-Matrix Analysis of Two-Color Coincidence Events in Single-Molecule Fluorescence Experiments. Yahiatène, Idir; Doose, Sören; Huser, Thomas; Sauer, Markus. In Analytical Chemistry, 84(6), S. 2729–2736. 2012.
  • Quantitative single-molecule microscopy reveals that CENP-ACnp1 deposition occurs during G2 in fission yeast. Lando, David; Endesfelder, Ulrike; Berger, Harald; Subramanian, Lakxmi; Dunne, Paul D.; McColl, James; Klenerman, David; Carr, Antony M.; Sauer, Markus; Allshire, Robin C.; Heilemann, Mike; Laue, Ernest D. In Open Biology, 2(7). 2012.
  • Super-resolution imaging reveals the internal architecture of nano-sized syntaxin clusters. Bar-On, Dana; Wolter, Steve; van de Linde, Sebastian; Heilemann, Mike; Nudelman, German; Nachliel, Esther; Gutman, Menachem; Sauer, Markus; Ashery, Uri. In Journal of Biological Chemistry. 2012.
  • Live-Cell Super-Resolution Imaging Goes Multicolor. Klein, Teresa; van de Linde, Sebastian; Sauer, Markus. In ChemBioChem, 13(13), S. 1861–1863. WILEY-VCH Verlag, 2012.
  • Follow-up to paper by S. Wolter, M. Schüttpelz, M. Tscherepanow, S. van de Linde, M. Heilemann and M. Sauer, entitled Real-Time Computation of Subdiffraction-Resolution Fluorescence Images. WOLTER, S.; SAUER, M. In Journal of Microscopy, 245(1), S. 109–109. Blackwell Publishing Ltd, 2012.
  • rapidSTORM: accurate, fast open-source software for localization microscopy. Wolter, Steve; Loschberger, Anna; Holm, Thorge; Aufmkolk, Sarah; Dabauvalle, Marie-Christine; van de Linde, Sebastian; Sauer, Markus. In Nat Meth, 9(11), S. 1040–1041. Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved., 2012.
  • Super-resolution imaging visualizes the eightfold symmetry of gp210 proteins around the nuclear pore complex and resolves the central channel with nanometer resolution. Löschberger, Anna; van de Linde, Sebastian; Dabauvalle, Marie-Christine; Rieger, Bernd; Heilemann, Mike; Krohne, Georg; Sauer, Markus. In Journal of Cell Science, 125(3), S. 570–575. 2012.
  • Live-Cell Super-Resolution Imaging with Synthetic Fluorophores. van de Linde, Sebastian; Heilemann, Mike; Sauer, Markus. In Annual Review of Physical Chemistry, 63(1), S. null. 2012.
  • Fluorescence localization microscopy: The transition from concept to biological research tool. Owen, Dylan M.; Sauer, Markus; Gaus, Katharina. In cib, 5(1942-0889), S. 0–1. Landes Bioscience Inc., 2012.
  • Superresolution Optical Fluctuation Imaging (SOFI). Dertinger, Thomas; Colyer, Ryan; Vogel, Robert; Heilemann, Mike; Sauer, Markus; Enderlein, Jörg; Weiss, Shimon. In Advances in Experimental Medicine and Biology, 733, E. Zahavy; A. Ordentlich; S. Yitzhaki; A. Shafferman (Hrsg.), S. 17–21. Springer Netherlands, 2012.
  • Dielectric Analysis and Multi-cell Electrofusion of the Yeast Pichia pastoris for Electrophysiological Studies. Terpitz, Ulrich; Letschert, Sebastian; Bonda, Ulrich; Spahn, Christoph; Guan, Chonglin; Sauer, Markus; Zimmermann, Ulrich; Bamberg, Ernst; Zimmermann, Dirk; Sukhorukov, Vladimir. In Journal of Membrane Biology, S. 1–12. Springer New York, 2012.