The sterlet (Acipenser ruthenus) (Photo: Andreas Hartl)

    Sturgeons lived on earth already 300 million years ago and yet their external appearance seems to have undergone very little change. A team of researchers from Würzburg and Berlin has now succeeded in sequencing their genome.

    A lung tumor that expresses USP28 (left). On the right, however, tumors are shown in which USP28 has been "cut out" using the gene editing tool CRISPR/Cas9 – they are significantly smaller. The size bar is located on the left edge of the picture.

    In squamous cell carcinoma, a protein ensures that unneeded proteins are no longer disposed of. A research team at the University of Würzburg has switched off this protein for the first time.

    Dr. Anna Stöckl at the JMU Biocentre. (Photo: Robert Emmerich)

    How do insects see the world? This is what Dr. Anna Stöckl wants to know. Her research program has now been awarded a distinction: she has been accepted into the Young Academy of the Bavarian Academy of Sciences and Humanities.

    Dwarf honeybee, giant honeybee and eastern honeybee (from left): researchers have studied the dance dialects of these three bee species.

    Honeybees use their waggle dance to tell their conspecifics where to find food. Depending on the honeybee species, there are different dance dialects, as a German-Indian research team has shown.

    This fluorescence microscopy image shows Campylobacter jejuni bacteria (green) that have infected human cells (HeLa). The nuclei of host cells are stained in blue and the cytoskeleton (actin) in magenta, respectively.

    Many bacterial pathogens develop resistance to antibiotics. In their search for new therapeutic strategies, Würzburg research groups employ modern digital technologies. The Free State of Bavaria provides millions for this purpose.


    Life in Dead Wood

    Sebastian Vogel, PhD student at the JMU’s Ecological Station, is taking dead wood samples for the genetic determination of fungi and bacteria.

    Dead wood plays an important role for biodiversity in forests. The Ecological Station of the University of Würzburg and the Forest Enterprise Ebrach conduct a joint research project on this topic that has been recently granted with 500,000 euros.

    LARP7-Expression in der Keimbahn von Mäusen. Gezeigt ist eine Immunfärbung des Proteins (grün), die Zellkerne sind mit einem Farbstoff (DAPI) blau markiert.

    Dwarfism and other developmental disorders are the consequences of a specific genetic defect. Researchers at the universities of Würzburg and Regensburg have now examined this gene in more detail.

    If metabolic networks of plants are modulated, they can bind significantly more carbon dioxide - and thus possibly slow down climate change.

    New technologies are needed to combat climate change. Now bioinformatics specialists from Würzburg might have found a way of enabling plants to store more carbon dioxide.

    It took months of computer work to decipher the spatial structure of the viral RNA polymerase. The picture shows the protein complex with its specific subunits from different sides.

    Vaccinia viruses serve as a vaccine against human smallpox and as the basis of new cancer therapies. Two studies now provide fascinating insights into their unusual propagation strategy at the atomic level.

    Wild honeybees at their nesting place in a tree cavity.

    The forests in Europe provide habitat for around 80,000 colonies of wild honeybees. That is why more attention should be paid to preserving the nesting sites for these threatened insects, according to researchers.

    Ingolf Steffan-Dewenter, Juliano Sarmento Cabral, Ludmilla Figueiredo und Jochen Krauß (v.l).

    If ecosystems are disturbed, this can trigger the extinction of species. For her research in this field, the journal Ecography awards biologist Ludmilla Figueiredo with a prize.

    Highly Cited Researchers 2019 at JMU: Hermann Einsele, Rainer Hedrich, Andreas Rosenwald, Ingolf Steffan-Dewenter, Hans Konrad Müller-Hermelink, Jörg Vogel, Frank Würthner, Laurens Molenkamp, and Christoph Wanner.

    Their work is most frequently cited in publications of other scientists. Eight researchers from the University of Würzburg have therefore been added to the Highly Cited Researchers 2019 List.