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THE BIOCENTER OF THE UNIVERSITY OF WÜRZBURG

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The distribution of the glutamate receptor mGluR4 and other proteins in the presynaptic membrane Left a high-resolution dSTORM image. On the right, the result obtained with conventional fluorescence microscopy – molecular details are not visible here.

"Distance keeping" is not exactly the motto of the glutamate receptors: Using high-resolution microscopy, it now was discovered that the receptors usually appear in small groups at the synapses and are in contact with other proteins.

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In expansion microscopy, the preparation is magnified more than four times. Here, a germ tube of Aspergillus fumigatus is shown before and after expansion; the scale corresponds to ten micrometers. The plasma membrane (turquoise) and the mitochondria (pink) were stained. (Picture: Ulrich Terpitz / University of Würzburg)

For the first time, the cells of fungi can also be analysed using a relatively simple microscopic method. Researchers from Würzburg and Cordoba present the innovation in the journal "Frontiers in Microbiology".

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