• HEK-293T cells infected with Chlamydia trachomatis expressing chlamydial deubiquitinase Cdu1-FLAG
Chair of Microbiology

Regulatory RNA in gonococcal infection

In recent years non-coding (nc) RNAs which act as post-transcriptional regulators in gene expression control were increasingly recognized as important components of regulatory networks in bacteria. Detection of ncRNAs has been boosted by the development of high-throughput RNA sequencing (RNA-seq) techniques and, not surprisingly, a considerable number of putative trans-acting small regulatory RNAs (sRNAs) and cis-acting antisense RNAs (asRNAs) was identified in the transcriptome of Neisseria gonorrhoeae. This project investigates the role of gonococcal ncRNAs in bacterial metabolism and Neisseria host interaction (read more).