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Deutsch
    Chair of Bioinformatics

    SEPARATOR

    SEPARATOR

    Separator is a program for decomposing large biochemical networks into smaller subsystems. This is helpful for avoiding combinatorial explosion of metabolic pathways. The source code was written by Thomas Pfeiffer (Zurich) and was debugged by the coauthor F. Moldenhauer. The decomposition procedure is published in Schuster et al. (2002).

    Click here for the Win32 program  and here for the source code in the programming language C.

    Reference

    Schuster S, Pfeiffer T, Moldenhauer F, Koch I and Dandekar T
    Exploring the Pathway Structure of Metabolism: Decomposing into Subnetworks and Application to Mycoplasma pneumoniae
    Bioinformatics 18, 351-361, 2002