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Chair of Bioinformatics

Shishir K Gupta

Contact

Shishir Kumar Gupta, Dr. rer. nat.

Evolutionary Genomics Group,
Center for Computational and Theoretical Biology,
Universität Würzburg,
97078 Würzburg, Germany

Department of Bioinformatics,
Biozentrum,
Universität Würzburg,
Am Hubland,
D-97074 Würzburg, Germany

Tel.: +49 (0)931 31 89747
Fax: +49 (0)931 31 84552

Email: shishir.gupta(at)uni-wuerzburg.de

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associated with FungiNET

Teaching

Topics in Bioinformatics
Topics in Systems Biology 

Publications (2018-22)

Role of the Pangolin in Origin of SARS-CoV-2: An Evolutionary Perspective
Gupta SK, Minocha R, Thapa PJ, Srivastava M, Dandekar T    
International Journal of Molecular Sciences, 2022 doi.org/10.3390/ijms23169115

Prediction and validation of host-pathogen interactions by a versatile inference approach using Aspergillus fumigatus as a case study
Balkenhol J, Bencurova E, Gupta SK, Schmidt H, Heinekamp T, Brakhage A, Pottikkadavath A, Dandekar T    
Computational and Structural Biotechnology Journal, 2022 doi.org/10.1016/j.csbj.2022.07.050

Sesquiterpenoids isolated from davana (Artemisia pallens Wall. ex DC) mitigates parkinsonism in Caenorhabditis elegans disease model
Trivedi M, Singh S, Pandey T, Gupta SK, Verma RS, Pandey R    
Biochemical and Biophysical Research Communications, 2022 doi.org/10.1016/j.bbrc.2022.04.005

An Ebola, Neisseria and Trypanosoma human protein interaction census reveals a conserved human protein cluster targeted by various human pathogens
Gupta SK, Ponte-Sucre A, Bencurova E, Dandekar T    
Computational and Structural Biotechnology Journal, 2021 doi.org/10.1016/j.csbj.2021.09.017

Alveolar Regeneration in COVID-19 Patients: A Network Perspective
Gupta SK, Srivastava M, Minocha R, Akash A, Dangwal S, Dandekar T    
International Journal of Molecular Sciences, 2021 22:20, p.11279 doi.org/10.3390/ijms222011279

Aspergillus fumigatus versus Genus Aspergillus: Conservation, adaptive evolution and specific virulence genes
Gupta SK, Srivastava M, Osmanoglu Ö, Xu Z, Brakhage AA, Dandekar T    
Microorganisms, 2021 9:10, p.2014 doi.org/10.3390/microorganisms9102014

Pathogen and Host-Pathogen Protein Interactions Provide a Key to Identify Novel Drug Targets
Gupta SK, Osmanoglu Ö, Srivastava M, Bencúrová E, Dandekar T    
Reference Module in Biomedical Sciences: Systems Medicine: Integrative, Qualitative and Computational Approaches: Elsevier, 2020, 2:543-553 doi:10.1016/B978-0-12-801238-3.11607-1

Aspergillus fumigatus Challenged by Human Dendritic Cells: Metabolic and Regulatory Pathway Responses Testify a Tight Battle
Srivastava M, Bencurova E, Gupta SK, Weiss E, Loffler J, Dandekar T
Front Cell Infect Microbiol, 2019, 9: 168 doi:10.3389/fcimb.2019.00168

C. elegans protein interaction network analysis probes RNAi validated pro-longevity effect of nhr-6, a human homolog of tumor suppressor Nr4a1
Akhoon BA, Gupta SK, Tiwari S, Rathor L, Pant A, Singh N, et al    Scientific reports, 2019, 9(1): 15711 doi:10.1038/s41598-019-51649-0

Genome-wide inference of the Camponotus floridanus protein-protein interaction network using homologous mapping and interacting domain profile pairs
Gupta SK, Srivastava M, Osmanoglu Ö, Dandekar T
Scientific reports, 2019, 10(1):2334 doi:10.1038/s41598-020-59344-1

Bioinformatics in Leishmania Drug Design
Gupta SK, Dandekar T
Drug Resistance in Leishmania Parasites: Springer, Cham, 2018, 2018: 297-317 doi:10.1007/978-3-319-74186-4_13

Omics and bioinformatics applied to vaccine development against Borrelia
Bencurova E, Gupta SK, Oskoueian E, Bhide M, Dandekar T
Mol Omics, 2018, 14(5): 330-40 doi:10.1039/c8mo00130h

Delay in antibiotic therapy results in fatal disease outcome in murine pneumococcal pneumonia
Berger S, Goekeri C, Gupta SK, Vera J, Dietert K, Behrendt U, et al
Crit Care, 2018, 22(1): 287 doi:10.1186/s13054-018-2224-5

Identification of Antifungal Targets Based on Computer Modeling
Bencurova E, Gupta SK, Sarukhanyan E, Dandekar T
J Fungi, 2018, 4(3): 81 doi:10.3390/jof4030081

Complete list of Publications