NP

This page collects four short videos that visualise platelet biology across scales — from the internal signalling state of a single cell, through morphological responses to its chemical environment, up to multi-cell flow and thrombus formation inside a realistic vessel geometry.

Each video uses a different tool chosen to suit its scale: Jimena/SQUAD for Boolean-network simulation of intracellular signalling, custom cell-behaviour models for morphology under dynamic activator gradients, and game-engine rendering (Unity) combined with meshes derived from expansion microscopy and lattice-lightsheet recordings of murine brain vasculature for the larger-scale scenes.

Together, the videos illustrate how computational models at different levels of abstraction can be composed into a coherent picture of platelet behaviour in vivo.

The collection accompanies an upcoming publication and is also archived on Zenodo with a citable DOI [link to be added once available]. Captions for each video appear directly below the players.