November 23rd, 2023
Laura Hauf's and Chris Reuter's Paper on tsetse-transmission of trypansomes to advanced skin models is published! Congratulations!
October 17th, 2023
Alyssa successfully defended her PhD thesis on the endo-lysosomal system of Trypanosoma brucei. Many congratulations!
October 4th -6th, 2023
We are hosting the 2nd workshop of the EU-ITN PHYMOT, a 3-day international meeting celebrating the movement of microbes
September 27th, 2023
The newest addition to the Engstler lab alumni. Congratulations!
July 18th, 2023
Nico Ankenbrand (left) and Daniel Bardolf (right) successfully completed their BTA training. Congratulations! We wish them all the best or their future careers!
June 13th, 2023
Check out on its friends!
June 1st, 2023
Dr Eli Meiser is the latest graduate of the Fenz Lab. Very well done Eli!!
May 24h, 2023
Check out Tom's new method for gene editing and scalable functional genomic screening in Leishmania species.
24th February 2023
"SUN4 is a spermatid type II inner nuclear membrane protein that forms heteromeric assemblies with SUN3 and interacts with lamin B3"
December 8th, 2022
Tom Beneke developed a CRISPR/Cas9 cytosine base editor toolbox for Leishmania that enables for the first time functional genetic screens via delivery of plasmid libraries. Check it out!
November, 23, 2022
It depends ... read Claudias Paper to find out. And Happy Birthday Claudia!
20th October 2022
Markus Engstler receives the Memento Research Prize in Berlin
October 6th, 2022
Fabian Link won the prize for the best talk. Congratulations!
September, 13-17, 2022
Seven of us presented at the Kinetoplastid Molecular Cell Biology Meeting (KMCBM IX) in Woods Hole (MA, USA)
30th August 2022
... the Kramer lab would not exist without you.
July, 30th, 2022
A great scientist and truly great human being has left us. We will never forget you. Rest in peace, Paul.
July 20th, 2022
Congratulations on successfully completing the biology laboratory assistant training!
(March 16th, 2022)
A characterisation of the TbSmee1 protein, with intriguing observations on cargo entry into trypanosomes.
Fun fact: 100% of the data for this preprint were obtained by undergraduates!
May 18, 2022 -- A103, 03:30 p.m.
Prof. Daniel Chourrout (Sars Centre, University of Bergen, Norway)
"Genomic Turbulence near Vertebrates"
May 9th 2022
The DFG-SPP 2332 'Physics of Parasitism' goes online
December 8th, 2021
Chris has already graduated in December. Time to put this in the news ;-)
April 14th, 2022
Hanna's work on Sun4 topology and interactions is now posted on the preprint server
April 1st, 2022
Five new researchers in our department: Franziska Schönhofer (B.A., Jones-Engstler), Nashmil Aslam (PhD, Jones-Engstler), Antonia Konle (PhD, Morriswood), Tom Beneke (Postdoc, Engstler) and Jose Carlos Quilles (Postdoc, Kramer).
March 25th, 2022
A new paper derived from a fruitful collaboration with our colleagues from the physiological chemistry and the human genetics departments
March 25th, 2022
This is Major Tom to Ground Control
I'm stepping through the door
And I'm floating in a most peculiar way
And the stars look very different today
March 24-25th, 2022
Inaugural meeting of the DFG priority programme 2332 held via Zoom.
March 1st, 2022
Joint statement of DVGeo, DPG, GDCh and VBIO concerning the war in Ukraine
February 21st, 2022
Spot the new doctor! Many congratulations!
January 10th, 2022
Uli Scheer hat die spannende Geschichte der Zoologie in Würzburg recherchiert. Wirklich sehr lesenswert!
November 9th, 2021
Nicole discovered an unexpected interaction between DOT1B and the Ribonuclease H2 protein complex. She opened the door to a new project with fantastic collaborators.
November 2nd, 2021
The results of our brilliant collaboration with the labs of Erec Stebbins and Nina Papavasiliou at DKFZ Heidelberg have been published. Well done to Alexander Hempelmann at DKFZ Heidelberg, Laura Hartleb and Kevin Bongers (ZEB Würzburg) and everyone else involved!
November 1st, 2021
The glycosylphosphatidylinositol (GPI) anchor: a linchpin for cell surface versatility of trypanosomatids
August 6th, 2021
We wanted to know what the VSG 16mer does and ended with the DExD/H protein Hel66. That's science ;-)
August 6th, 2021
Finally! Our paper on the life cycle of Trypanosoma brucei is published. It was a long struggle against dogmatic unbelief.
August 6th, 2021
To the surface and back – exo- and endocytic pathways in Trypanosoma brucei
July 2nd, 2011
Ten years ago, our dear colleague Norbert Wilken passed away. We have not forgotten him!
June 29th, 2021
We show that many ApaH like phosphatases can decap mRNAs in vitro. But only Kinetoplastids actually USE the enzyme for mRNA decapping in vivo. They are special! (We always knew this)
June 25th, 2021
Congratulations on successfully defending your PhD thesis, Erick! Very well done!
June 22nd, 2021
Very suprisingly, we have data showing that the active ES is also transcriptionally attenuated
May 12th, 2021
Majeed's work on the DExD/H protein Hel66 is is on the preprint server. Congrats!
May 14th, 2021
Chris Reuter's opus magnum is finished!
May 5th, 2021
Erick's work on mRNA-balancing is out. Read it!
May, 5th 2021
We are ALL negative. Lisa can go to the beer garden soon, without testing, but she wont taste the beer :-(
April, 14th, 2021
Many congratulations Carina! Well done!
April 8th, 2021
Single cell motility in trypanosome 2D collectives.
April 7th, 2021
The identification of a SWR1 complex provides insights into transcriptional regulation in T. brucei
March 24th, 2021
New review from the Kramer lab
January 15th, 2021
Great collaboration with Erec Stebbins et al. and some real surprises on the trypanosome surface.
December 19th, 2020
Why is it, that only trypanosomes use extraterrestrical (ok, bacterial) proteins for mRNA decapping?
December 10th, 2020
New paper from the Morriswood group, with high-resolution structures of the MORN1 protein from Trypanosoma brucei, Toxoplasma gondii, Plasmodium falciparum.
Dec 4th, 2020
October 5th, 2020
Nicole Eisenhuth defends her PhD thesis on the histone methyl-transferase DOT1B in Trypanosoma brucei (and Leishmania).
October 5th, 2020
A fruitful collaboration with Markus Sauer’s lab published in Nature Communications
October 5th, 2020
Irene da Cruz’ work on the evolutionary history of meiotic telomere anchoring to the nuclear envelope
October 5th, 2020
Human infertility, meiosis and the synaptonemal complex
October 2nd, 2020
Markus Engstler elected vice-president of VBIO
September 25th, 2020
Marie-Christin Spindler defends her thesis on the molecular organization of the meiotic nucleus. Amazing data.
September 5th, 2020
New paper from the Janzen lab.
August 7th, 2020
"Gemeinsamer Promotionspreis der Unterfränkischen Gedenkjahrstiftung für Wissenschaft und der Universität Würzburg" goes to Sarah Schuster
August 5th, 2020
New preprint on phylogeny: nice collaboration with the bioinformatics department
July 29th, 2020
Irene defended her PhD thesis, on how telomeres connect to the nuclear membrane during meiosis. Well done !
July 20th, 2020
A new Preprint from ZEB.
May 26th, 2020
DFG funds the new priority programme PoP coordinated by Markus Engstler
April 28th, 2020
Detailed analysis of lamin C2 expression in mouse oocytes
April 24th, 2020
There is no way of stopping the wish for proper scientific discussion.
April 20th, 2020
A beautiful collaboration with Alvaro Acosta-Serrano in Liverpool!
April 4th, 2020
Motility Analysis of Trypanosomatids: Here are the methods we have developed
March 10th, 2020
A CRISPR/Cas9 knock out model for SUN3 demonstrated the essential function of SUN3 in sperm head shaping
February 10th, 2020
Familial primary ovarian insufficiency due to a SYCE1 point mutation
February 10th, 2020
Paper by visiting scientist Fernanda Trovero on lncRNAs in spermatogenesis published in RNA Biology
January 31st, 2020
Hello to all our friends in the UK!
January 29th, 2020
The DZVT has been officially launched
January 23th, 2019 -- A 103, 09:15
What can planarians teach us about cell regulation?
December 19th, 2019
The ZEB-Xmas-party takes it's toll
December 16th, 2019
Sarah graduates with distinction (summa cum laude). Well done!
December 12th, 2019 -- A 103
Isabel talks about the sweet and sour tale of social motility (SoMo) and African trypansomes.
December 12th, 2019
Quantitative electron tomography data published in Scientific Reports
December 12th, 2019
Special issue on “Recent advances in meiosis from DNA replication to chromosome segregation” published by Chromosoma
November 28th, 2019 -- A 103
How the flow is regulated in the endoplasmic reticulum
November 26th, 2019
Markus Engstler on the panel of DAAD's Cosimena conference in Cairo
November 14th, 2019 --- A103, 09:15
Skin pharmacokinetics and anti-parasitic pharmacodynamics: towards the design of new treatments for cutaneous leishmaniasis.
November 8th, 2019
Paula Castaneda honored by the Brazilian Society of Protozoology in Caxambu
October 31st, 2019
A new preprint, in collaboration with Kristina Djinovic-Carugo's group (Max Perutz Labs, Vienna). Structures of MORN repeat proteins from trypanosomes and apicomplexans, and an analysis of lipid binding.
October 29th, 2019
A collaboration with Markus Sauer’s lab
October 21st, 2019
Marie-Christin Spindler’s work published in Communications Biology
October 17th, 2019 -- A 103
Philippe comes along and talks about 'How do motors find the way?'. Join us!
October 15th, 2019-- C102.3, 10:15
Bruno Dallagiovanna visits from Brazil and will lecture on 'Long non-coding RNAs in heart development'
August 2nd, 2019
Sarah Schuster's work on the trypanosome passage through the tsetse fly was awarded one of this years Science Awards. Congratulations!
July 30th, 2019
We have a new preprint on the life cycle of trypanosomes.
July 17, 2019-- C102.3, 11:00
Rohit Shrivastava will talk about the role of the translation initiation factor eIF4E3 during the Leishmania life cycle.
July 4th, 2019 -- C102.3, 10:15
Acquired unsaturated fatty acid catabolism: A feature on the trypanosomatid's way to intracellular parasitism.
June 27th, 2019 -- C102.3, 10:15
Exploiting the tsetse biology for trypanosomiasis control
May 22, 2019
The Würzburg DZVT is inaugurated in the presence of Dr Gerd Müller, Federal Minister of Economic Cooperation and Development
May 16th, 2019 -- C102.3, 10:15
The control of Leishmania flagellum beating and swimming - new lessons from high speed fluorescence microscopy
April 4th, 2019
How does the African trypanosome control expression of its Variant Surface
Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma
March 21st, 2019
Roberta Sciurano’s work published in Chromosoma
March, 21st, 2019 -- A103, 09:15
Brice will tell us what happens "When African trypanosomes make your skin crawl"
March 7th, 2019 -- A103, 09:15
Jack Sunter will give a ZEB lecture on 'Leishmania flagellar pocket architecture is critical for pathogenicity'.
February 21st, 2019 -- A103, 09:15
Trypanosome AMP-dependent protein kinase activation induces developmental transition from proliferative to the quiescent form: Novel players in the pathway.
February, 7th, 2019 -- A103, 09:15
Sascha Knauf (Deutsches Primatenzentrum, Göttingen) will lecture on "Disease Reservoirs in Wildlife: from Eco Health to One Health"
January 23th, 2019 -- A103, 09:15
TrypClub this week will be given by Sara Sajko (Max F. Perutz Laboratories, Vienna), discussing her PhD project work.
January 24th, 2019 -- A103, 09:15
Exploitation of receptor-mediated ligand uptake for the targeted delivery of antibody-drug conjugates into Trypanosoma brucei.
January 10th, 2019 -- A103, 09:15
We welcome Annette MacLeod from Glasgow, who will give the first ZEB-lecture in 2019. Happy New Year!
December 31st, 2018
Collaboration with Owen Davis’ lab on meiotic telomeres published in Nature Communications.
December 31st, 2018
Paper by visiting scientist Roberta Sciurano on meiosis in a 47, XYY man published in Human Reproduction.
December 18th, 2018
We are very happy to be part of a collaboration headed by Nicolai Siegel's lab, which explored the influence of genome organisation and DNA accessibility on antigenic variation in African trypanosomes.
December 13th, 2018 -- A103, 09:15
Investigating and exploiting parasites weaknesses in lipid and associated metabolism
November 12th, 2018
Trypanosomes can start (but not finish!) nuclear export even when transcription and splicing have not been completed.
November 15th, 2018 -- A103, 09:15
Elucidating specificity mechanisms in ubiquitin signaling
October 31th, 2018
Collaboration with Thomas Bosch’s lab on the nuclear lamina of non-senescent Hydra published in Aging (Albany, NY).
October 23rd, 2018
The complex enzymology of mRNA decapping: Enzymes of four classes cleave pyrophosphate bonds.
October 22th, 2018 -- C102.3, 12:00 noon
Spliced leader level is a signal for life and affects social motility via exosome secretion in trypanosomes
October 18, 2018 -- A103, 09:15 a.m.
Functional dissection of the Leishmania flagellar proteome using CRISPR-Cas9 knockout screens
October 4th, 2018
New hints about how excess of prelamin A induces muscle fiber weakness during physiological and premature aging.
October 4th, 2018 -- A103, 09:15 a.m.
Human African Trypanosomiasis: Evolution and Cell Death in Trypanosoma brucei.
September 26, 2018 -- A101, 01:15 p.m.
Single-molecule fluorescence microscopy in live Trypanosoma brucei and model membranes
September 20th, 2018 -- A102, 10:45 a.m.
Function and composition of Trypanosoma brucei mitochondrial DNA: use it or lose it.
September 1st, 2018
We have published a review/opinion article in 'Trends in Parasitology', in which we consider the recently extended definition of the interstitium as path for the dispersal of extracellular pathogens.
August 29th, 2018
A unique, historic portrait of the founder of Würzburg Zoology has been moved from our department to the Martin von Wagner Museum, where it will be prominently displayed in the entrance hall.
August 27, 2018
Marie-Christin Spindler’s experimental protocols published in Methods in Molecular Biology.
August 23rd, 2018
Markus Engstler, together with DNTDs and DAHW, presents the Würzburg concept for a Neglected Tropical Diseases Center
July 25th, 2018
Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA.
July 16, 2018 -- Seminar A102.3, 11:00 a.m.
Nutrient stress during Giardia dudenalis infection: Who cares about arginine?
July 12th, 2018 -- Seminar A102.3, 10:15 a.m.
The lullaby of Sleeping Sickness
July 1, 2018
Markus Engstler delivers evening lecture at the 11th International Workshop on Engineering of Functional Interfaces
June 28, 2018
Katharina Schücker’s experimental protocols published in Methods in Cell Biology
June 28, 2018 -- Seminar A102.3, 10:15 a.m.
Meiotic arrest in infertile men due to genetic disturbances
June 20-22, 2018
Keynote lecture by Ricardo Benavente at the 4th Spanish Meiosis Meeting
June 12-22, 2018
Advanced electron microscopy for cell biology.
Christian Stigloher, together with Gareth Griffiths and Yannick Schwab, has organized this years EM course, which will take place in our Z7 course building.
June 10-15, 2018
Ricardo Benavente lectured at the Gordon Research Conference on Meiosis (New London, New Hampshire)
June 14th, 2018 -- Seminar A102.3, 10:15 a.m.
How to build a flagellum: Lessons from Trypanosomes
May 31th to June 3rd, 2018
Our work featured is as part of the University's Africa initiatives.
May 30th, 2018 -- Seminar A102.3, 10:15 a.m.
How SPOC executes the Nerve Pinch through transcriptional regulation
Im Mai besuchen uns Nachwuchsforscher aus der Kita an der Löwenbrücke, am 7.Mai die Grossen und am 29. Mai die Kleinen.
May 5, 2018 -- Seminar C102.3, 10:15 a.m.
Optical Microspectrometry for studying the underlying dynamics of life: from phase transitions to mechano-transduction
April 23, 2018
Weakening of lamin crosslinks by site specific phosphorylation supports meiotic chromosome movements
April 19, 2018 -- Seminar C102.3, 10:15 a.m.
Life cycle differentiation and the cytoskeleton in Trypanosoma brucei
April 10, 2018
Die erste wissenschaftliche Studie zum Beitrag deutscher Institutionen bei der Forschung zu Vernachlässigten Tropenerkrankungen wird im Bundesministerium für Bildung und Forschung (BMBF) in Berlin vorgestellt. Markus Engstler ist einer der Herausgeber der Studie.
March 28, 2018
Boehringer Ingelheim Fonds awarded Marie a travel grant to take part in the Cold Spring Harbor Laboratory course on Quantitative Imaging
March 28, 2018
We warmly welcome Roberta Sciurano (Buenos Aires) and Fernanda Trovero (Montevideo) who will spend six months in the Benavente lab
March 26, 2018 -- C101.2, 10:00 a.m.
Trypanosomes' magic bullet – Understanding the structural basis of SRA-mediated immune escape in T. b. rhodesiense
March 23, 2018
Sarah (arrow) receives DGP-poster prize for her tsetse fly work
March 21-24, 2018
Eleven of us presented at the Parasitology Meeting in Berlin
March 14, 2018
We have launched a comprehensive online resource that features Theodor Boveri's life and work.
February 17, 2018
Tim Krüger's (nature-inspired) vision of a trypanobot on the issue cover of Micromachines
February 16, 2018
Uli Scheer publishes the rediscovery of Boveri's microscope slides in Würzburg.
February 14, 2018
Interested in doing your PhD in our interdisciplinary department? Perfect time to join us!
February 8, 2018
Novel components of the telomeric shelterin complex were identified in Trypanosome brucei.
February 2, 2018
Science or fiction? Can we design trypanosome-inspired micro-robots? Read our new review.
February 1, 2018
Advance notice for M.Sc. students. Our brand-new module will start in April.
January 25, 2018 -- A103, 09:15 a.m.
Size-dependent organelle transport during phagocytosis
January 17, 2018
Our work on VSG structure and dynamics featured by the European Synchrotron Radiation Facility (ESRF)
January 7, 2018
New review in Cellular Microbiology
November 21, 2017
Our friend and coworker Prof Andrew Nok has passed away. With deep sorrow we remember his brilliant intellect, his kindness and wonderful sense of humor. Markus Engstler
November 13, 2017 -- A103, 09:15 a.m.
Electron cryo microscopy as tool in structural biology
November 13, 2017
Find your favorite thesis project! We are continuously updating the selection of topics ...
November 13, 2017
Ricardo Benavente appointed „Investigador Emérito“ by the Clemente-Estable-Institute for Biological Research in Montevideo
November 8, 2017
Sarah's work in eLIFE featured by Cambridge-based BPoD
November 16, 2017 -- A103, 09:15 a.m.
Structural dissections of the flagellar pocket collar in Trypanosoma brucei and a novel oligomeric lysine methyltranferase from Toxoplasma gondii
October 16, 2017
We welcome all new (and old) students to the winter term. Hope you like our lectures, seminars and courses!
October 12, 2017
The school, co-organized by Susanne Kramer, has been honored by the HRK
September 18 to 22, 2017
Markus Engstler lectured at the International School "From single particle motion to collective behaviour".
September 11, 2017
Our work on the structure-function relationship of VSG published in Nature Microbiology
August 15, 2017
Sarah's work published in eLife
July 27, 2017 -- A103, 09:15 a.m.
MPI Biochemie, Martinsried
Dynamic Mapping of Protein Subcellular Localization through Quantitative Proteomics
July 19, 2017 -- A101, 02:30 p.m.
July 18, 2017
...we have started to launch our new websites ... will take a while ....
July 13, 2017 -- A103, 09:15 a.m.
“Paraphagy”, a new autophagy mechanism for Leishmania immune evasion?
June 28, 2017 -- A101, 05:15 p.m.
Adaptive fine tuning of genetic information by DNA mutation and RNA editing
June 21, 2017 -- A101, 02:30 p.m.