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Lehrstuhl für Zell- und Entwicklungsbiologie

HANNA THOMA

Nucleocytoplasmic junction in germ cells

During final differentiation to mature fertilization competent sperms, the haploid spermatids undergo a typical morphological transformation that includes a profound nuclear compaction and reshaping from round to elongated. Although this process is key determinant of male fertility, the underlying mechanisms are hardly understood. I try to figure out the specific function of selected components of the nucleocytoplasmic junction in the formation of a functional, regularly shaped sperm head.

(AG Alsheimer)

 

Room C105.6

 +49 (0)931 31-89865

 hanna.thoma(at)uni-wuerzburg.de