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Lehrstuhl für Zell- und Entwicklungsbiologie

Nicole Eisenhuth

Discovering new functions for the histone methyl-transferase DOT1B in Trypanosoma brucei

Dot1 enzymes are conserved histone methyltransferases that can be found in most eukaryotic organisms. The methylation mark of Dot1 is associated with many cellular processes such as telomeric silencing, transcriptional control, cell cycle regulation, DNA repair and developmental differentiation. The parasite Trypanosoma brucei has two Dot1 enzymes, DOT1A and DOT1B. DOT1B is essential for developmental differentiation from the mammalian to the insect stage of the parasite. The aim of my PhD research is to characterize the molecular machinery, which enables DOT1B to execute its functions.

Room C124

Tel ++49 93131 86342

nicole.eisenhuth@uni-wuerzburg.de

Kontakt

Lehrstuhl für Zoologie I - Zell- und Entwicklungsbiologie
Am Hubland
97074 Würzburg

Tel.: +49 931 31-84250
Fax: +49 931 31-84252
E-Mail

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Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Julius-von-Sachs-Platz 2 Fabrikschleichach Hubland Süd, Geb. B2 Campus Medizin